Navigation Links
COPD patients experience poorer sleep quality and lower blood oxygen levels
Date:9/20/2012

Patients with chronic obstructive pulmonary disease (COPD) experience poorer sleep quality than people of a similar age without COPD, according to research published in the journal Respirology.

Researchers also found an independent relationship between how well patients with COPD slept and the oxygen levels in their arterial blood.

"Patients with COPD frequently report fatigue, sleepiness and impaired quality of life," says Professor Walter McNicholas from the Department of Respiratory and Sleep Medicine at St. Vincent's University Hospital, Dublin, Ireland.

"The study carried out by our group, which has been researching sleep and breathing for more than 25 years, showed that such patients experience poor sleep quality, which may contribute to these debilitating symptoms."

COPD is the name for a collection of lung diseases, including chronic bronchitis, emphysema and chronic obstructive airways disease. People with COPD have trouble breathing in and out because of long-term damage to their lungs, usually because of smoking. COPD is now the fourth leading cause of chronic death and ill health in the USA and is projected to rank fifth in the burden of disease worldwide.

The current study provides a secondary analysis of two previously published trials investigating the impact of long-acting bronchodilators on night-time oxygen saturation in 106 patients with established, moderate to severe COPD. Bronchodilators make breathing easier by relaxing the muscles in the lungs and widening the airways.

Poor sleep quality was measured in a number of ways, including a reduced percentage of rapid eye movements (REM), which occur during the deepest level of sleep.

The patients covered by the study had an average age of just over 66 years, 67 per cent were male and all were current or former smokers, with a smoking history of ten or more years. Strict clinical criteria were applied to the subjects, which are outlined in full in the paper.

Key findings of the study included:

  • Patients with severe COPD experienced poorer sleep quality than people without COPD of a similar age.
  • Daytime hypoxemia (low arterial blood oxygen levels) is associated with sleep efficiency, but airflow obstruction is not. Hypoxemia is thought to impact on certain neurotransmitter levels and these mechanisms can contribute to poor sleep efficiency.
  • COPD patients took longer to fall asleep than the age-matched controls after the lights had been turned off (sleep latency) and spent less of their time in bed sleeping (sleep efficiency). They also experienced greater differences in the way they slept, with more sleep at the lightest level (stage one) and less at REM (stage five, the deepest level). Slow wave sleep (stages three and four) was reasonably well preserved.

"Our study highlights poor sleep quality in patients with COPD and demonstrates an association between daytime hypoxemia and sleep efficiency," concludes Professor McNicholas.

"However, sleep quality in COPD is determined by several factors and further studies on this topic are necessary to fully evaluate the relationship. This may identify therapeutic interventions that might improve the overall quality of life in COPD patients."


'/>"/>

Contact: Amy Molnar
sciencenewsroom@wiley.com
Wiley
Source:Eurekalert

Related medicine news :

1. The cost of glaucoma care: Small group of patients accounts for large part of costs, study finds
2. Most Forehead Lift Patients Recommend Procedure: Survey
3. Cleveland Clinic study shows vitamin E may decrease cancer risk in Cowden syndrome patients
4. Considerably more patients may benefit from effective antidiabetic drug
5. Sound level around seriously ill patients like a busy road
6. Simple tool may help evaluate risk for violence among patients with mental illness
7. Study: Gingko biloba does not improve cognition in MS patients
8. Cystic fibrosis patients of low SES are less likely to be accepted for lung transplant
9. Perceived control affects complication rates in patients with acute coronary syndrome
10. Physicians suggest expert recommendations ignore vital issues for patients
11. Docs Sensitivity to Patients Feelings Tied to Good Outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... Petersburg Florida (PRWEB) , ... March 28, 2017 , ... ... Marine Corp to raise money to for the Toys for Tots Literacy Campaign at ... federal budget in excess of $70 billion, the U.S. ranks at number 14 internationally ...
(Date:3/28/2017)... ... March 28, 2017 , ... AutismOne announced ... American Association of Integrative Medicine and available for application on Saturday, May 27, ... 2017 Conference in Colorado Springs. , Ed Arranga, president of AutismOne, stated: "Many ...
(Date:3/28/2017)... ... March 28, 2017 , ... The ... in Atlantic City March 13-16, was a busy spot this year. Liz Solovay ... discussed strategies for preventing outbreaks among camp communities during the upcoming 2017 camping ...
(Date:3/28/2017)... ... ... a common and unwelcomed occurrence in people of all ages, genders and ethnicities. Dermatologist Dr. ... of dealing with excess skin oil. “Oily skin is a challenge to many of my ... the oily shine while keeping the skin fresh and clean,” says Dr. Au. , What ...
(Date:3/28/2017)... ... ... thrilling adventure that reveals the mystery of Kevin’s purpose. “A Prophets Bones” is the creation ... asked of him that he had neglected to do, but this was from God and ... some who would have felt themselves to be special and better than others due to ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... BOSTON , March 28, 2017 /PRNewswire/ ... today announced a partnership with premium news ... allows pharmaceutical companies to extract key insights from ... text mining technology. The Linguamatics I2E ... top 20 global pharmaceutical companies. The Linguamatics-Dow Jones ...
(Date:3/28/2017)...  Akcea Therapeutics, a subsidiary of Ionis Pharmaceuticals, Inc. (NASDAQ: ... directors: Christopher Gabrieli , ... as chairman of the board of Akcea Therapeutics. ... Forest Laboratories. Sandford D. Smith , ... "We are excited to announce this expansion to our ...
(Date:3/28/2017)... RXi Pharmaceuticals Corporation (NASDAQ: RXII), a ... significant unmet medical needs, today announced that it ... Office (JPO) for the composition of matter of ... the treatment or prevention of fibrotic disorders, including ... retinopathy (Japanese Patent #: 6060071).  This patent includes ...
Breaking Medicine Technology: