Navigation Links
CNIO scientists successfully test the first gene therapy against aging-associated decline
Date:5/14/2012

to the cells. The authors selected demonstrably safe viruses that have been successfully used in gene therapy treatment of haemophilia and eye disease. Specifically, they are non-replicating viruses derived from others that are non-pathogenic in humans.

This study is viewed primarily as "a proof-of-principle that telomerase gene therapy is a feasible and generally safe approach to improve healthspan and treat disorders associated with short telomeres", state Virginia Boccardi (Second University of Naples) and Utz Herbig (New Jersey Medical School-University Hospital Cancer Centre) in a commentary published in the same journal.

Although this therapy may not find application as an anti-ageing treatment in humans, in the short term at least, it could open up a new treatment option for ailments linked with the presence in tissue of abnormally short telomeres, as in some cases of human pulmonary fibrosis.

More healthy years

As Blasco says, "ageing is not currently regarded as a disease, but researchers tend increasingly to view it as the common origin of conditions like insulin resistance or cardiovascular disease, whose incidence rises with age. In treating cell ageing, we could prevent these diseases".

With regard to the therapy under testing, Bosch explains: "Because the vector we use expresses the target gene (telomerase) over a long period, we were able to apply a single treatment. This might be the only practical solution for an anti-ageing therapy, since other strategies would require the drug to be administered over the patient's lifetime, multiplying the risk of adverse effects".


'/>"/>

Contact: Juan J. Gomez
juanj.gomez@cnio.es
34-917-328-000-4060
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists Pinpoint Area of Brain That Fears Losing Money
2. Scientists Discover How HIV Is Transmitted Between Men
3. Prevention Is Key Research Goal for Premature Babies, Scientists Say
4. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
5. Scientists find donut-shaped structure of enzyme involved in energy metabolism
6. Neuroscientists reveal new links that regulate brain electrical activity
7. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. Scientists Spot Genetic Fingerprints of Individual Cancers
10. Scientists Unravel Mysteries of Intelligence
11. MSU scientists develop more effective method of predicting lead-poisoning risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CNIO scientists successfully test the first gene therapy against aging-associated decline
(Date:7/25/2014)... July 25, 2014 Mahendra Trivedi and ... Online Workshop ‘Consciousness is Power’ on Saturday, July 26, ... to attend this life transforming event as they will ... higher level. Few days are left for the commencement ... Trivedi and Trivedi Masters™ Dahryn Trivedi (his wife) and ...
(Date:7/25/2014)... CMS recently has imposed a series ... inadequate access to prescription drugs. Agency audits are uncovering ... safety of beneficiaries in areas such as rejected pharmacy ... is taking quick and firm actions to halt them. ... “Avoiding Costly Part D Sanctions: Rx Access Strategies ...
(Date:7/25/2014)... 25, 2014 Yisrayl Hawkins, Pastor and Overseer ... on his blog explaining why so many prayers are going ... , In the article, Yisrayl gives many examples around ... the results. For example, in one case, in the small ... grounds to pray for rain; ironically, they received a massive ...
(Date:7/25/2014)... Yisrayl Hawkins, Pastor and Overseer of The House of Yahweh ... revealing to the whole world, including even the most devout ... in his new article. , Yisrayl says it all started ... by the Catholic Church. He says this plan included removing ... and replacing it with titles such as Lord and God. ...
(Date:7/25/2014)... According to the Hemorrhoid ... Vkool.com, this is a comprehensive guide that ... common types of hemorrhoids including:, ...     Young children with hemorrhoids , ...     Very large hemorrhoids and chronic hemorrhoids , ...
Breaking Medicine News(10 mins):Health News:Mahendra Trivedi to Host an Online Workshop ‘Consciousness is Power’ 2Health News:Mahendra Trivedi to Host an Online Workshop ‘Consciousness is Power’ 3Health News:Aug. 5 Webinar to Offer Strategies for Preventing Rx Access Issues and Avoiding Part D Sanctions 2Health News:Yisrayl Hawkins Says Prayers for Rain Result in Violent Hail Because Prayers Are Not Being Heard in New Post 2Health News:Yisrayl Hawkins Says Prayers for Rain Result in Violent Hail Because Prayers Are Not Being Heard in New Post 3Health News:Yisrayl Hawkins Says You Have Been Tricked Into Worshipping Satan in New Article 2Health News:Hemorrhoid No More Pdf Review Exposes Jessica Wright's Guide For Treating Hemorrhoids – Vkool.com 2Health News:Hemorrhoid No More Pdf Review Exposes Jessica Wright's Guide For Treating Hemorrhoids – Vkool.com 3
... SANTA MONICA, Calif., Oct. 8 Proposed,regulations that ... California stem cell research grants to for-profit organizations ... cures for California taxpayers,paying for the research, the ... "To ensure that the people who have ...
... Precise Surgical Laser Procedures, CAMBRIDGE, Mass., Oct. ... laser fibers for precision surgery, announced today,the launch ... procedures. The LightPath fiber features a fine ... safely conduct more precise procedures in Laryngology,Head & ...
... their own ... personal health info, PHILADELPHIA, Oct. ... largest organization of its,kind, will ask select groups of Americans to ... for,themselves, their children and ailing loved ones. At its 79th Annual,Convention ...
... like most, you eat worst at healthy restaurants., The ... treat themselves to higher-calorie side dishes, drinks or desserts ... no health claims, according to a series of new ... version of the Journal of Consumer Research , ...
... patients more likely to develop dementia, study finds ... people with Parkinson,s disease face up to a 73 ... new study that says genetics could be to blame. ... central nervous system, such as impaired motor skills and ...
... New research shows that selective serotonin reuptake inhibitors ... depression, may double the risk of gastrointestinal bleeding, according ... and colleagues. When the drugs are taken with aspirin ... than 600 percent higher. , Clinicians who prescribe these ...
Cached Medicine News:Health News:Revised California Stem Cell Research Rules Fail to Ensure Affordable Access to Cures, Consumers Warn 2Health News:OmniGuide Announces Launch of LightPath(TM) CO2 Laser Fiber 2Health News:AHIMA National Consumer Awareness Campaign Urges Patients to Assume Responsibility of Personal Health Records 2Health News:'Healthy' restaurants help make us fat, says a new Cornell study 2Health News:Parkinson's Linked to Risk of Alzheimer's 2Health News:Anti-depressant drugs can double risk of gastrointestinal bleeding 2Health News:Anti-depressant drugs can double risk of gastrointestinal bleeding 3
(Date:7/24/2014)... WASHINGTON , July 24, 2014  The ... Brightree is supporting its mission to help address ... new and exclusive agreement to be the information ... service. As the leading provider of billing and ... brings unmatched HME industry expertise to support this ...
(Date:7/24/2014)... Consolidated Net Profit increased by 43.65 % to Rs. 1848.46 ... India Business grew by 20.87% to Rs. 3,971.59 Mn ... Rest of World (ROW) Business grew by 20.67% to Rs. 2,113.09 ... 977.26 Mn Latin America Business grew by 33.92% to ... the research-led global integrated pharmaceutical company, today announced its results for ...
(Date:7/24/2014)... -- "North America Orthopedic Braces and Supports Market Outlook ... America Orthopedic Braces and Supports market. The report provides ... units) and average price data (in US dollars), within ... , Ankle Braces and Supports , Spinal ... Supports. Photo - http://photos.prnewswire.com/prnh/20140723/129806 ...
Breaking Medicine Technology:Brightree Joins AAHomecare as Corporate Partner and IT Lead on HME Audit Key 2Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 2Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 3Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 4North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 2North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 3North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 4North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 5
... ANGLETON, Texas, June 2, 2011 Benchmark Electronics, Inc. ... manufacturing provider, announced today that a product it helped ... Design Excellence Award and 2011 Edison Award for best ... 3M™ Integrated Cycler, which has won a 2011 Medical ...
... 2, 2011 Craneware, Inc., the market leader ... multi-year agreement today with Kingman Regional Medical Center, ... Recognized as one of the nation,s five star ... will add Craneware InSight Denials® to the range ...
Cached Medicine Technology:Benchmark Electronics Recognized as Supplier for 2011 Design Medical Excellence Award Winner 2Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 2Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 3Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 4
... Cool Line catheter is inserted into the ... the superior vena cava. The Cool ... have sterile, temperature-controlled saline flowing within a ... the central circulation. The Cool Line ...
...
... ability of interventional cardiologists and cardiothoracic ... and provides non-interventional cardiologists with a ... of patients who have become refractory ... a noninvasive, atraumatic treatment for coronary ...
Our smallest port is available with either a COOK Peel-Away or COOK Micropuncture Introducer Set....
Medicine Products: