Maris draws on the internationally prominent expertise of Stephan A. Grupp, M.D., Ph.D., and Tom Curran, Ph.D., to lead the CHOP-based research programs. Grupp has developed the first highly effective childhood cancer immunotherapy, in collaboration with Carl H. June, M.D., of the Perelman School of Medicine at the University of Pennsylvania. It was Grupp's efforts that resulted in Emily Whitehead's remarkable recovery from her lethal leukemia and her attendance at the press conference today.
"We were excited to experience this great outcome with Emily," said Grupp, who added, "Although this is an early result, it offers the promise of a significant advance against this high-risk childhood leukemia. Our goal on the Dream Team is to emulate this success in treating other pediatric cancers."
Oncology researcher Tom Curran is a member of the Institute of Medicine, and was recently named to the AACR's inaugural class of Fellows of the AACR Academy. He will lead the brain tumor discovery efforts at CHOP, interacting closely with Maris's own research program in neuroblastoma. CHOP will serve as the central hub for data analysis and new therapy development across the Dream Team consortium. The full list of Dream Team leaders and investigators at CHOP can be viewed online.
The Dream Team will focus on the four most deadly pediatric cancers: malignant brain tumors, high-risk leukemias (such as the type of acute lymphoblastic leukemia that Emily Whitehead had), neuroblastomas (which affect the peripheral nervous system) and sarcomas (other tumors of bone and other tissue).
Recent research in genomics, said Maris, has shown that pediatric cancers are fundamentally different from adult can
|Contact: Rachel Salis-Silverman|
Children's Hospital of Philadelphia