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CEL-SCI Presents Favorable Data for Leaps Vaccine Technology at Prestigious Immunology Conference
Date:6/9/2008

immune system to fight viral diseases. They also may lead to new treatments against autoimmune diseases by redirecting established immune responses, stopping their attack upon the body."

The LEAPS vaccine consists of a portion of an HSV or HIV protein attached to a portion of another very small protein (immune cell binding ligand (ICBL)) chosen to promote and direct the immune response to the virus. By themselves, neither the ICBL nor the viral peptides initiate protection but when conjugated together, the LEAPS vaccines promote immune responses that can protect against HSV-1.

Vaccination against HSV and HIV has the potential to prevent initial infection; prevent or lessen the severity of disease; and prevent spread of the virus to sexual partners as well as to neonates and newborns. The LEAPS vaccines is one of several approaches to the development of safe and effective vaccines are being pursued.

About CEL-SCI Corporation:

CEL-SCI Corporation is developing products that empower immune defenses. Its lead product is Multikine(R). In Phase II clinical trials Multikine was shown to be safe and well-tolerated, and to improve the patients' overall survival by 33% at a median of three and a half years following surgery. The U.S. Food and Drug Administration (FDA) gave clearance for a Phase III clinical trial with Multikine in January 2007 and granted orphan drug status to Multikine in the neoadjuvant therapy of squamous cell carcinoma (cancer) of the head and neck in May 2007.

Multikine, a patented defined mixture of naturally derived cytokines, is the first immunotherapeutic agent in a new class of drugs called "Immune SIMULATORS". Immune SIMULATORS simulate the way our natural immune system acts in defending us against cancer. As opposed to other immunotherapies which are designed to target a single or limited number of specific antigens or molecules, Immune SIMULATORS are multi-targeted; they simultaneously cause a direct and target
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SOURCE CEL-SCI Corporation
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