Navigation Links
CDC Issues New TB Treatment Guidelines

THURSDAY, Dec. 8 (HealthDay News) -- New guidelines on treating so-called "latent" tuberculosis infection in the United States should significantly shorten and simplify the course of the therapy from about 9 months to 3 months, according to the U.S. Centers for Disease Control and Prevention.

The new guidelines for public health officials and health care providers -- which are based on expert opinion and the results of three clinical trials -- are a "game changer" for the treatment of TB in the United States, according to CDC Director Dr. Thomas Frieden.

Latent TB infection occurs when a person is infected with TB bacteria but does not yet have symptoms and so cannot transmit the bacteria to others. However, if the bacteria becomes active, the person will develop the disease and can also spread it to others.

Certain people, including those with weakened immune systems, are more likely to progress from latent to active TB. The CDC notes, however, that many high-risk people with latent TB feel fine and don't begin the nine-month course of treatment, which typically requires 270 daily doses of the anti-TB drug isoniazid. And many of those who do begin the therapy don't see it through to the end.

However, the new regimen streamlines the treatment to 12 once-per-week doses of isoniazid, along with another anti-TB drug called rifapentine.

"This regimen has the potential to be a game-changer in the United States when it comes to fighting TB," Frieden said in a CDC news release. "It gives us a new, effective option that will reduce by two-thirds -- from nine months to three months -- the length of time someone needs to take medicine to prevent latent TB infection from progressing to active TB disease."

The new guidelines were published in the Dec. 9 issue of the CDC's Morbidity and Mortality Weekly Report.

"If we are going to achieve our goal of TB elimination in the United States, we must ensure that those with latent TB infection receive appropriate evaluation and treatment to prevent their infection from progressing to TB disease and possibly spreading to others," Dr. Kevin Fenton, director of CDC's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, said in the news release.

"It is critical that we accelerate progress against TB in the United States in order to avoid a resurgence of the disease," he added.

The number of people in the United States with TB remains at an all-time low, with just over 11,000 cases reported in 2010. However, about 4 percent of the U.S. population (11 million people) are infected with the TB bacterium. The CDC also noted that foreign-born people and people of color in the United States are disproportionately affected by the illness.

These new guidelines apply only to the United States, CDC officials said. Further research is likely needed before this regimen could be recommended for countries with a high incidence of TB, particularly those that have high rates of HIV and where there's a greater risk of TB re-infection.

More information

The American Lung Association has more about TB.

-- Robert Preidt

SOURCE: U.S. Centers for Disease Control and Prevention, news release, Dec. 8, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. American Society of Clinical Oncology issues annual report on progress against cancer
2. AAOS issues new clinical practice guideline for treating common elbow fractures in children
3. Experts Design Toolkit to Help Spot Teens With Mental Health Issues
4. Programming cells to home to specific tissues may enable more effective cell-based therapies
5. Study highlights issues faced by friends and family of the suicidal
6. People With Mental Health Issues More Likely to Be Uninsured
7. Rebooting the system: Immune cells repair damaged lung tissues after flu infection
8. Academic issues warning on schoolboy rugby
9. CDC Issues Guidance for Coping With Lingering Heat
10. ADHD, Learning Issues May Be Linked to Secondhand Smoke
11. Emotional, Behavioral Issues Affect Many Kids in Foster Care
Post Your Comments:
Related Image:
CDC Issues New TB Treatment Guidelines
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
(Date:6/24/2016)... , ... June 24, 2016 , ... June 19, 2016 ... dangers associated with chronic pain and the benefits of holistic treatments, Serenity Recovery ... are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its ... Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding ... Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, we ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)... Ill. and INDIANAPOLIS , ... students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is ... 2016 scholarship winners, announced today online at ... let type 1 diabetes stand in the way of ... has supported the Foundation,s scholarship program since 2012, and ...
(Date:6/23/2016)... -- Revolutionary technology includes multi-speaker listening to ... leaders in advanced audiology and hearing aid technology, has ... the world,s first internet connected hearing aid that opens ...      (Photo: ) , ... firsts,: , TwinLink™ - the first dual ...
Breaking Medicine Technology: