Navigation Links
C-Section Stress Could Alter Baby's Immune Cells
Date:7/2/2009

And that might raise odds for diabetes, asthma later on, researchers say

THURSDAY, July 2 (HealthDay News) -- Babies delivered by cesarean section experience changes to the DNA of white blood cells, which might explain why they're at increased risk for immunological diseases such as diabetes and asthma later in life, Swedish researchers say.

"Delivery by C-section has been associated with increased allergy, diabetes and leukemia risks," Dr. Mikael Norman, a pediatric specialist at the Karolinska Institute in Stockholm, said in a news release from Wiley-Blackwell publishers. "Although the underlying cause is unknown, our theory is that altered birth conditions could cause a genetic imprint in the immune cells that could play a role later in life."

Norman and his colleagues analyzed blood samples from 37 infants taken just after delivery and samples taken three to five days after birth. The blood was analyzed to assess the degree of DNA-methylation in the white blood cells, which are a key part of the immune system. In DNA-methylation, DNA is chemically modified to activate or turn off genes in response to changes in the external environment.

The 16 infants born by C-section had higher DNA-methylation rates immediately after delivery than the 21 infants born by vaginal delivery, according to the report, in the July issue of Acta Paediatrica. Three to five days after birth, both groups of infants had similar levels of DNA-methylation.

Further research is needed to determine why infants born by C-section have higher DNA-methylation rates after delivery, the researchers said.

"Animal studies have shown that negative stress around birth affects methylation of the genes, and therefore it is reasonable to believe that the differences in DNA-methylation that we found in human infants are linked to differences in birth stress," the researchers wrote.

"We know that the stress of being born is fundamentally different after planned C-section compared to normal vaginal delivery," they explained. "When babies are delivered by C-section, they are unprepared for the birth and can become more stressed after delivery than before. This is different [from] a normal vaginal delivery, where the stress gradually builds up before the actual birth, helping the baby to start breathing and quickly adapt to the new environment outside the womb."

More information

The Nemours Foundation has more about cesarean delivery.



-- Robert Preidt



SOURCE: Wiley-Blackwell, news release, June 29, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Risk to Baby Rises With Repeat C-Sections
2. Using C-Section Scars to Predict Future Deliveries
3. Early Elective C-Sections Produce Complications
4. Rate of Unnecessary C-Sections Far Lower Than Thought
5. C-Section Might Boost Babys Asthma Risk
6. Patience during stalled labor can avoid many C-sections, UCSF study shows
7. C-Sections Explain Jump in U.S. Preemie Births
8. C-sections a critical factor in preterm birth increase
9. C-Sections a Critical Factor in Preterm Birth Increase
10. Possible biological explanation for C-Section-linked allergies and asthma found
11. Malpractice Premiums, Rate of C-Sections Rise Together
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
C-Section Stress Could Alter Baby's Immune Cells
(Date:10/13/2017)... ... October 13, 2017 , ... The ... to promote standards of excellence for the field of eating disorders, announces the ... – 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers ... companies have a waiver for care if the client has a cognitive impairment diagnosis. ... pays for care, is often waived, so the benefits from their insurance start immediately,” ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized ... have expanded their existing home health joint venture through an agreement, effective October ... a joint venture home health company with Asante, delivering clinically integrated care, for ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... Oct. 4, 2017 OBP Medical ... illuminating medical devices, today announced regulatory approval from ... Agency (or Agência Nacional de Vigilância Sanitária (ANVISA)) ... cordless surgical retractor with integrated LED light source ... illumination and exposure of a tissue pocket or ...
(Date:10/2/2017)... PHILADELPHIA , Oct. 2, 2017 Halo Labs announces ... particle analysis system called the HORIZON at MIBio 2017 in ... analyzes subvisible and visible particulate matter in biopharmaceutical samples with unprecedented ... use of the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: