Navigation Links
C-Section, Formula May Disrupt 'Good' Gut Bacteria in Babies

By Amanda Gardner
HealthDay Reporter

MONDAY, Feb. 11 (HealthDay News) -- Being born by cesarean section has been tied to higher risks for various health problems in children, and now a new study finds these babies also have fewer "good" bacteria in their digestive tract.

Similarly, babies who were exclusively or even partially formula-fed rather than breast-fed also had markedly different gut flora than babies who were breast-fed, according to the study appearing in the Feb. 11 issue of the CMAJ (Canadian Medical Association Journal).

"Since other [researchers] have found associations between cesarean section delivery or formula-feeding and infant gut changes and conditions like allergy [and] asthma, we speculate that our observations may lead to poor health in later life," said study senior author Anita Kozyrskyj.

The findings support current clinical practice guidelines which favor vaginal delivery whenever possible, added Kozyrskyj, who is research chair and an associate professor of pediatrics at the University of Alberta, in Edmonton.

About a third of all U.S. births occur by C-section, a number considered by many to be far too high and potentially harmful to both the child and the mother.

Vaginal delivery, among other advantages, fosters the growth of trillions of good bacteria that reside peacefully in the human body (collectively know as a person's microbiome), many of them in the intestine.

Meanwhile, C-sections interfere with the newborn's exposure to bacteria in the vaginal tract, bacteria that essentially trains the immune system to react appropriately to future events, according to study background information.

Mothers who have C-sections also tend to start breast-feeding later and require antibiotics, both of which could also affect the baby's microbiome.

In the new study, researchers analyzed DNA from fecal samples taken from 24 healthy infants in four Canadian provinces at 4 months of age.

Compared with children who had been born vaginally, children who had been delivered by C-section had less diverse flora, lower levels of Shigella bacteria and none of the bacteria known as Bacteroides at all.

"Shigella and Bacteroides are organisms picked up from mom and considered first colonizers," Kozyrskyj explained. "They lay the foundation for further microbes that become part of our normal microbiome."

Meanwhile, infants who were fed formula as opposed to breast milk also had less diverse flora and, in addition, had more of the bacteria Clostridium difficile, which had been associated with the development of allergies.

The study was a small one, but the researchers have collected fecal samples on 200 children and will be analyzing those in the future. They hope to eventually enroll 2,500 children in the study.

It's too soon to say definitively that the changes in the gut microbiome of children born by C-section will develop health problems. And it's possible that changes in the bacterial composition of the intestine as people age will compensate for diminished levels of bacteria in newborns, Kozyrskyj added.

A pediatric expert praised the new study.

"This is an important first step to make an association between intestinal bacteria and mode of delivery and type of feeding," said Dr. Michael Morowitz, a pediatric surgeon with Children's Hospital of Pittsburgh, at the University of Pittsburgh Medical Center.

Although follow-up studies will be needed, Morowitz added, "This is the latest piece of pretty convincing evidence that determinants very, very early in life can have an impact that lasts for months or years."

More information

Visit the U.S. National Institutes of Health for more on the Human Microbiome Project.

SOURCES: Anita Kozyrskyj, Ph.D., research chair and associate professor, pediatrics, University of Alberta, Edmonton; Michael Morowitz, M.D., pediatric surgeon, division of pediatric general and thoracic surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center; Feb. 11, 2013, CMAJ (Canadian Medical Association Journal)

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New weight loss formula by Fort Max Diet burns fat without suppressing appetite for food
2. ACP applauds introduction of bipartisan bill to eliminate Medicare SGR formula
3. Neuroplenish Offers A Bottle of Neuropathy Pain Relief Formula
4. Jay Altman’s 28-day Fat Loss Formula Announced
5. Zion Health Announces Native Remedy-Natural Clay Toothpaste without Fluoride formulated to help Prevent Gum Disease. Now Available At Whole Foods Market in Lafayette, CA.
6. FDA Urges Studies on Safer Formulations of Narcotic Painkillers
7. Everyday Vitamin Adds Jarrow Formulas Products to Supplement Roster
8. Harvokse Announces Worldwide Expansion for Worlds Only Proven Hair Growth Formula
9. Capsiplex Fat Burner Formula with Red Pepper and Other Useful Ingredients for Quick Weight Loss
10. Swanson Health Products Introduces Xanthigen® Liver Fat Formula to Support Healthy Liver Function
11. New Hair Loss Treatment Formula Released for Balding Men Online by Provillus
Post Your Comments:
Related Image:
C-Section, Formula May Disrupt 'Good' Gut Bacteria in Babies
(Date:12/1/2015)... ... December 01, 2015 , ... Growth in medical payments per workers’ compensation ... utilization of hospital and nonhospital care, according to a recent study by the Workers ... 16th Edition , found medical payments per claim with more than seven days of ...
(Date:12/1/2015)... ... December 01, 2015 , ... It’s official: Tattoo taboo is ... a number even greater among Millennials (a whopping one in three aged 18 to ... people who are dissatisfied with their ink. In fact, RealSelf , the world’s ...
(Date:12/1/2015)... ... 01, 2015 , ... For many X-rays taken at hospitals, ... interpretation by the radiologist. The marking utensils are so small, however, they are ... a way to alleviate this problem. , He developed the patent-pending MARK N ...
(Date:12/1/2015)... ... 01, 2015 , ... Next IT Healthcare, the leader in ... this year’s Fierce Innovation Awards: Healthcare Edition, an awards program from the publisher ... in the category of Digital Solutions for its innovative, industry-leading product, Alme Health ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... Effective Post-Affiliation Integration ,” addresses a main “pain point” for merging or aligning ... results, once a deal is signed. This quick-read guidance suggests that failing ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Calif. , Dec. 1, 2015 ... products and services, announced today that it has been ... services organization. Members served by Novation will have access ... devices, sports bracing products and soft goods dedicated to ... --> The aging U.S. population, rising prevalence ...
(Date:12/1/2015)... 2015 Russia has always been ... of new drugs registered in Europe in 2015 ... --> Russia has always been a country of ... registered in Europe in 2015 were tested in ... Russia has always been a country of choice for ...
(Date:12/1/2015)... CytRx Corporation (NASDAQ: CYTR ), a ... announced that it has reached its enrollment target of ... clinical trial of aldoxorubicin in patients with previously treated ... completed in Q1 2016. The Phase 3 trial is a ... Assessment from the FDA at 79 sites in ...
Breaking Medicine Technology: