Navigation Links
Bypass not to blame for heart patients' mental decline
Date:5/19/2008

Heart patients often experience lasting problems with memory, language, and other cognitive skills after bypass surgery. However, these problems arent caused by the surgery itself or the pump used to replace heart function during surgery, a new study by Johns Hopkins researchers suggests. The findings may lead to better approaches to prevent cognitive decline regardless of which treatment heart disease patients receive.

The study, published in the May Annals of Neurology, compared cognitive function of patients who received cardiac bypass surgery with that of patients who received other treatments for coronary artery disease, including pharmaceuticals and stents. After testing all the study subjects periodically in a variety of cognitive areas for six years after their treatments, the researchers found that both groups experienced an almost identical decline in cognitive function. The results suggest that the disease itself, and not any particular treatment, is the cause for cognitive decline.

Previous studies have linked bypass surgery to patients mental decline, with many doctors blaming the bypass pump that keeps blood flowing through the body during surgery. This research led many doctors to avoid recommending surgery to their patients. However, Hopkins researcher Guy McKhann explains that previous studies hadnt compared patients who had bypass surgery to those who had other treatments instead. As such, its been unknown whether mental decline is a consequence of surgery using the bypass pump, heart troubles, part of the normal aging process, or another cause altogether.

To gather evidence, McKhann and other Hopkins researchers recruited 152 heart disease patients who were scheduled to undergo bypass surgery and 92 patients whose doctors planned to treat their heart disease in other ways, including stents and medications. The patients, mostly men, had an average age of about 64.

Before their treatments, the researchers gave each of the patients a battery of 15 different mental tests meant to examine cognitive functions including memory, motor speed, attention, and the ability to plan ahead. Then, at three months, one year, three years, and six years after treatment, the researchers gave the volunteers the same tests to see whether their cognitive function had changed.

When they compared the two groups results, the researchers found similar results. Both groups started out with comparable cognitive abilities, which improved slightly for about a year after treatment. However, over the next five years, most of the patients experienced a similar decline of cognitive function in almost every area tested, regardless of whether they had surgery or another treatment.

These results suggest that neither bypass surgery nor the pump itself causes cognitive decline, says McKhann. He says that the finding may help the stigma that prevents some doctors from recommending bypass surgery.

We dont think fear of mental changes should be a factor in deciding what kinds of treatments you have for your heart, he adds.

Since both groups of patients scored lower than healthy patients on similar cognitive tests in other studies, McKhann notes that he and other researchers believe that coronary artery disease is the culprit. However, he says, he and his colleagues dont believe that cognitive decline is an inevitable consequence of heart disease.

If we take a very aggressive approach to treating risk factors for heart disease, including keeping a handle on diabetes, blood pressure, and weight, patients may be able to avoid these cognitive problems, McKhann says.


'/>"/>

Contact: Christen Brownlee
cbrownlee@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. Restricting Blood Flow May Help Heart Bypass Patients
2. Bypass Off-Pump Boosts Womens Outcomes
3. Rehabilitation significantly underused after heart attack and bypass surgery
4. Angioplasty Equals Bypass Surgery for Heart Patients: Study
5. Lung Bypass Could Fight Emphysema
6. Statins After Bypass Lower Stroke Risk
7. Video: Patient at Mother Frances Receives Heart Bypass Without Opening Chest
8. Researchers at Peoria Pulmonary Associates to study airway bypass procedure for emphysema
9. Stents Slightly Better Than Bypass for Blocked Left Coronary Artery
10. Cardicas C-Port Anastomosis Systems for Coronary Artery Bypass Graft Procedures to be Used to Train Cardiothoracic Surgeons at Society of Thoracic Surgeons (STS) University
11. New York Methodist Hospital to study airway bypass treatment for emphysema
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... February 26, 2017 , ... ... lab became the world’s first to be ISO/IEC 17025:2005 INAB accredited for Der ... , ISO/IEC 17025:2005 is the globally recognised standard that sets out requirements for ...
(Date:2/26/2017)... , ... February 26, 2017 , ... ... wholesale distribution in North America, today announced it would be offering some it’s ... which prides itself on crafting quality and unique baby clothing/feeding products, will team ...
(Date:2/26/2017)... ... February 26, 2017 , ... ... standard in staffing, scheduling, and reporting for healthcare organizations. This comprehensive and ... the entire staffing process. StaffBridge technology improves staffing efficiency, maximizes resource allocation, ...
(Date:2/26/2017)... Florida (PRWEB) , ... February 26, 2017 , ... ... (PD) patients after receiving cognitive rehabilitation, according to a study released today at ... known that cognitive rehabilitation programs are proven to be effective in improving cognitive ...
(Date:2/25/2017)... ... 25, 2017 , ... FCPX users now have the ability to sharpen a ... ProSharpen Color users have total control over sharpening amount, sharpening radius, threshold, horizontal sharpening, ... spectrum tools users can visually see the color range effected with ease all within ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... , Israel and TAMPA, Fla. , ... an emerging medical device company focused on developing ... procedures, applauds the members of the FDA,s Circulatory ... for their acknowledgement of the need for cerebral ... "The statements shared by this FDA ...
(Date:2/27/2017)... 2017 Now in its seventh year, ... are most successful at developing and commercialising innovation. ... The Index can ... molecule to two different companies in early phase, which would ... objective analysis of each company,s performance between 2011 and 2016, the 2017 ...
(Date:2/27/2017)... Period October – December 2016 ... to SEK -16.4 (-6.4) million Result after tax amounted to ... after dilution Cash flow from operating activities amounted to SEK ... Period full ... Operating result amounted to SEK -39.5 (-29.5) million ...
Breaking Medicine Technology: