Navigation Links
Burning Heart Tissue Beats Atrial Fibrillation
Date:1/26/2010

If drugs don't work, catheter ablation does the job, study finds

TUESDAY, Jan. 26 (HealthDay News) -- When drug therapy can't control the dangerous heart rhythm disorder called atrial fibrillation, burning out the cardiac tissue responsible for the abnormality will do the job in most cases, a new study has found.

Called catheter ablation, the burning technique ended episodes of abnormal heartbeat and improved the quality of life over a nine-month period for two-thirds of the people in the study who had the procedure, compared with 16 percent of those who were started on a new drug regimen.

The finding was reported in the Jan. 27 issue of the Journal of the American Medical Association.

In atrial fibrillation, the upper chambers of the heart have episodes in which they quiver rather than beat to circulate blood. The episodes are often uncomfortable, causing chest tightness, pain and other symptoms. In addition, clots can form in the stagnant blood, traveling to block arteries and causing heart attacks or strokes. An estimated 2 million Americans have the condition, which becomes more common with aging.

A variety of drugs are used to treat atrial fibrillation, but initial drug therapy will not satisfy about half the people with the condition, said study author Dr. David J. Wilber, who is director of the Cardiovascular Institute at Loyola University Medical Center in Illinois.

"What has become clear is that once you fail one drug, your chances of responding to another drug are limited," he said. At that point, Wilber said, he might suggest catheter ablation, in which an electrical impulse is transmitted to eliminate the source of the irregular heartbeat.

The study, done at 19 hospitals in the United States and abroad, included 167 people whose atrial fibrillation was not controlled by one or more drugs. Of that group, 106 people had catheter ablation treatment and 61 were given a different drug. The trial was cut short because of the obvious advantages of catheter ablation, the researchers reported.

But that does not mean that catheter ablation is the first choice for treatment of atrial fibrillation, Wilber noted. He said he suggests it only when drug therapy clearly is not working, with the choice largely left up to the person with the condition.

"Some patients may say they want to try anything else first, some say they want the invasive procedure [catheter ablation]," he said. "This study offers the possibility of catheter ablation replacing drug therapy in these cases because the trial shows those patients do better."

Catheter ablation does have its risks, Wilber acknowledged. Previous studies have found a complication rate of 1 percent to 5 percent, he said. No such complications were seen in the new study.

"The amount of heart tissue that is destroyed has a relatively small effect on heart function," Wilber said. "That tissue isn't missed by the heart as much as you might expect."

And though many large medical centers are equipped for catheter ablation, expertise in the technique can differ, he said. "There is a very large range of experience," Wilber said. People considering the procedure should check published reports of clinical trials for evidence of a given medical center's expertise.

"I don't think there is a simple way right now" to do this, Wilber said, adding that "there is considerable interest in a national registry, as for heart surgery."

Dr. Frank Marchlinski, director of the electrophysiology program at the University of Pennsylvania and a member of the research team, said the study "demonstrates convincingly that, with catheter ablation, the outcome is dramatically better."

Like Wilber, Marchlinski said he, too, would suggest the procedure when drug therapy isn't working.

"I give patients that information, describe the opportunity of catheter ablation and the risk of catheter ablation," Marchlinski said. "I tell them that there is only a 20 percent chance of long-term success with other drugs."

But because atrial fibrillation generally is not immediately life-threatening, "it doesn't mean with absolute certainty it has to be done," he said. "This is an elective procedure. It is appropriate to consider it for those who do not want to take drugs."

More information

The U.S. National Heart, Lung, and Blood Institute has more on catheter ablation.



SOURCES: David J. Wilber, M.D., professor, medicine, and director, Cardiovascular Institute, Loyola University Medical Center, Maywood, Ill.; Frank Marchlinski, M.D., professor, medicine, and director, electrophysiology program, University of Pennsylvania, Philadelphia; Jan. 27, 2010, Journal of the American Medical Association


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. 9,000 NYC Buildings Burning Dirty Heating Oil Identified in New Report
2. Natural Pepper Skin Sprays Stop Any Itch In Minutes Without Burning
3. Nevada Burning Man Festival Sees Giant Aerial Marijuana Bud Banner That Protests Hydroponics Hijacking
4. The Vegan Monologues Asks the Burning Question: Is That a Carrot in Your Pocket?
5. Pacific Shore Holdings, Inc. Launches Burner Balm a Revolutionary, Energy-Boosting, Appetite-Suppressing, Fat-Burning Lip Balm - Natural, Green and Cost-Effective - Featured on NBCs Today Show
6. Online Diets Reviewed: Your Top 4 Metabolism Boosting, Fat Burning Plans
7. Georgia State researchers shed light on fat burning
8. Targeted nanospheres find, penetrate, then fuel burning of melanoma
9. Particulate Emission from Natural Gas Burning Home Appliances Is Assessed in Environmental Engineering Science Journal
10. Burning incense increases risk of respiratory tract cancers
11. Closing coal-burning power plant in China and improved cognitive development in children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... Anxiety of older Americans over ... of Medicare Part D a decade ago, according to The Senior Citizens League ... on how they are coping with rapidly rising costs. “The implications are chilling, ...
(Date:2/10/2016)... ... February 09, 2016 , ... According to a recent ... dramatic increase in the number of patients under the age of 30. According to ... seeing in their offices, and may indicate an overall shift in the rapidly growing ...
(Date:2/9/2016)... Nevada (PRWEB) , ... February 09, 2016 , ... ... providing treatment to Medicaid beneficiaries who are diagnosed with autism spectrum disorder (ASD). ... Nevada. Autism treatment using applied behavior analysis (ABA) is key to providing ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... compensation fee schedule rates and Medicare rates for a variety of medical services ... report, Evaluation of the 2015 Fee Schedule Rates in Illinois, are ...
(Date:2/9/2016)... NY (PRWEB) , ... February 09, 2016 , ... Establishment ... appointment of Dr. David Hung to the company´s Board of Directors. , ... world class scientist and an exceptional entrepreneur.” said Juan Jose Chacon Quiros, CEO of ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... 2016  Increasingly, health care professionals are enhancing patient ... wireless technology. With the Vios Monitoring System from Vios ... remotely detect problems before they become serious by continuously ... the United States . ... --> The Vios Monitoring System connects ...
(Date:2/9/2016)... Feb. 9, 2016  Johnson & Johnson (NYSE: ... Global Healthcare Conference on Tuesday, Feb. 23, at the ... Caruso , Vice President, Finance & Chief Financial Officer ... represent the Company in a session scheduled at 10:00 ... --> www.investor.jnj.com . --> This webcast ...
(Date:2/9/2016)... , Feb. 9, 2016 Athenex, Inc. announced ... as Vice President of Corporate Strategy and Business Development based ... MBA has joined as Senior Director and Deputy Head of Clinical Research ... . Simon Pedder stated, "Athenex has a ... a while. Coupled together with their unique business model and ...
Breaking Medicine Technology: