Navigation Links
Building a better flu vaccine: Add second strain of influenza B
Date:4/6/2010

ST. LOUIS -- Vaccines likely would work better in protecting children from flu if they included both strains of influenza B instead of just one, Saint Louis University research has found.

"Adding a second influenza B virus strain to the seasonal influenza vaccine would take some of the guesswork out of strain selection and help improve the vaccine's ability to prevent influenza," said Robert Belshe, M.D., lead investigator and director of the Center for Vaccine Development at Saint Louis University.

"Since in five of the last 10 years, the influenza B component in the vaccine has been the incorrect one, this seems like an obvious advance to me."

Every spring, scientists predict which strain of influenza will be circulating in the community the following fall. Historically, they choose two different subtypes of influenza A and one of influenza B. When they choose the wrong strain of influenza B, the influenza vaccine is less effective in preventing the disease.

Research findings in the March issue of Vaccine highlight the importance of adding both lines of influenza B into the vaccine to better protect against the flu.

The research team examined how well current vaccines protect against influenza B by looking at the immune response of ferrets that were given FluMist, a live attenuated influenza vaccine manufactured by MedImmune, and at efficacy studies in children who received traditional flu shots or FluMist.

When ferrets were vaccinated against influenza, the ferrets that were exposed to a strain of influenza B virus that did not match what was in the vaccine didn't have a strong antibody response. However they had a vigorous antibody response when given a vaccine that contained both strains of influenza B. This showed that immunizing against one strain of influenza B does not appear to protect against the other strain and that a vaccine containing both influenza B strains is likely to offer greater protection from flu.

Similarly, children who received influenza vaccines that contained a strain of influenza B that matched what was circulating in the community were less likely to get the flu than those whose vaccines didn't match the circulating strain of influenza B.

"These data highlight the need for vaccination strategies that provide enhanced protection against both lineages of influenza B," Belshe said.

"The pathway to further improving influenza vaccines for children is to include antigens of both influenza B virus strains in the vaccine."


'/>"/>

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University
Source:Eurekalert  

Related medicine news :

1. Morehead Presents Webinar on “Building Employee Engagement in a University Healthcare Environment”
2. ACS webinar features tips for finding and building a career in the food and flavor industries
3. Doctor Building Nutritarian Army to Fight Disease
4. 60-Day Free Community Confidence Building and Self-Defense Training
5. Ted Kennedy - Healthcare Rest in Peace Memorial Protest at Senate Russell Building
6. Former Hospital and Office Buildings in Mesquite, Texas, up for Sealed Bid Auction from Sperry Van Ness Accelerated Marketing
7. UM Clinical Research Building awarded prestigious LEED Building Certification
8. 9,000 NYC Buildings Burning Dirty Heating Oil Identified in New Report
9. Healthcare Trust of America, Inc. Acquires the Smyth Professional Building Located in Baltimore, Maryland
10. Edifecs Continues Building a Stellar Management Team
11. Ecumen Building Senior Housing in Apple Valley, Minnesota and Will Manage New Maplewood, Minnesota Property
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Building a better flu vaccine: Add second strain of influenza B
(Date:6/23/2017)... Beach, CA (PRWEB) , ... June 23, 2017 , ... ... has earned its ninth consecutive four-star rating from premier online charity evaluator, Charity Navigator, ... in the top 1% of all charities reviewed by Charity Navigator and earns ANRF ...
(Date:6/23/2017)... ... June 24, 2017 , ... Studies show evidence that ... the risk of visual loss in these patients. , But how often do ophthalmologists ... smoking cessation to patients at risk of or with early symptoms of AMD? A ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... practicing in Newburgh, New York, has recently begun offering three new minimally invasive ... the best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited to bring ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... Everybody has ... it while others prefer to read it, and some people don't like it at ... pornography. Here's what they found: , Erotic literature can give readers a taste of ...
(Date:6/23/2017)... ... 2017 , ... The Aesthetic Channel has recently highlighted Dr. Ben Talei’s unique ... a proprietary technique that he calls the AuraLyft Facelift. The AuraLyft does ... patients can expect to look refreshed, rejuvenated, and revitalized. , Dr. Talei’s unique ...
Breaking Medicine News(10 mins):
(Date:6/20/2017)... 2017  Hill-Rom Holdings, Inc. (NYSE: HRC), will host its ... Friday, July 28, 2017, beginning at 7:30 a.m. (CDT) / ... information: To participate in the conference call, dial (877) 304-8969 ... at least 10 minutes prior to the start to allow ... Webcast: A simultaneous webcast of ...
(Date:6/16/2017)... , June 16, 2017  Exactly 50 years ago ... off what later became known as the San Francisco "Summer ... ) is unveiling two radical innovations in strategic market research ... This announcement marks the beginning of Northern Light,s "Summer of ... ...
(Date:6/14/2017)... WINSTON-SALEM, N.C. , June 14, 2017  In ... the Creative Startups pitch competition and came ... virtual reality platform is described by Forbes as "entering ... the American Medical Association as teaching "empathy to medical ... success, the startup was recently named a finalist for ...
Breaking Medicine Technology: