Navigation Links
Building a better Rift Valley fever vaccine
Date:6/27/2012

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne pathogen.

The African virus causes fever in humans, inflicting liver damage, blindness, encephalitis and even death on a small percentage of those it infects. It also attacks cattle, sheep and goats, producing high mortality rates in newborn animals and causing spontaneous abortions in nearly all infected pregnant sheep.

In 2000, outbreaks of Rift Valley fever in Yemen and Saudi Arabia showed that the virus could expand beyond its original range. With this and the rapid North American spread of West Nile virus in mind, infectious-disease experts have long feared that Rift Valley fever virus might come to the United States or Europe, causing major human suffering and devastating the livestock industry in affected areas.

"If Rift Valley fever virus were introduced to the U.S. or Europe, it would be a very scary situation," said UTMB assistant professor and Sealy Center for Vaccine Development member Tetsuro Ikegami, lead author of a paper on the vaccine work now online in the Journal of Virology. "To be ready to respond, we want a vaccine that can raise immune response very quickly in large animals and health workers. We also want a vaccine that will allow us to differentiate between infected and vaccinated animals."

Ikegami's first requirement quick response dictated the use of a so-called "live attenuated vaccine." A live attenuated vaccine is a strain of virus that has been weakened to harmlessness, but still has the ability to reproduce and provoke a robust immune response. Such vaccines often require only a single injection, increasing speed and convenience of administration.

A live attenuated vaccine for Rift Valley Fever virus already exists, a strain called MP-12. MP-12 pr
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Body Building, Diet Supplements Linked to Liver Damage: Study
2. Germ Culprits in Moldy, Water-Damaged Buildings Identified
3. A better tool to diagnose tuberculosis
4. Job injuries among youth prompt calls for better safety standards
5. Students focus on creating a better cervical collar
6. Out-of-hand tree nut consumption associated with better diet quality in children and adults
7. Kidney cancer patients do better when whole kidney is not removed, U-M study shows
8. Kidney Cancer Patients Fare Better With Tumor Removal Only
9. New Psoriasis Drugs Not Much Better Than Standard Therapy, Study Finds
10. Hispanics Seem to Have Better Odds of Lung Cancer Survival
11. Which ads are winners? Your brain knows better than you do
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... specifically associated with the risk of a difficult-to-diagnose ... of all breast cancer cases. , The largest ... invasive lobular carcinoma, gives researchers important clues to ... breast cancer, which can be missed through screening. ... journal PloS Genetics , was co-led by ...
(Date:4/17/2014)... of the most popular vaccine brands for children may ... be overlooking some cost factors when choosing vaccines, driving ... option, according to a new study by University of ... can be driven by numerous factors," says Sheldon H. ... of computer science and of mathematics at the U. ...
(Date:4/17/2014)... the April issue of Experimental Biology and ... Drs. Rex Gaskins and Paul Kenis in the ... of the University of Illinois Urbana-Champaign describe their ... reactions underlie a variety of cell functions including ... these crucial roles in regulating normal cellular behavior, ...
(Date:4/17/2014)... recent papers by a University of Colorado School ... develop treatments or vaccines for Dengue fever, West ... disease-causing flaviviruses. , Jeffrey S. Kieft, PhD, associate ... School of Medicine and an early career scientist ... recently published articles in the scholarly journals ...
(Date:4/17/2014)... Le Bonheur Children,s Hospital Pediatrician-in-Chief Jon McCullers, MD, ... the April issue of Nature Reviews Microbiology ... Dr. McCullers, a world-renowned infectious disease specialist, ... the University of Tennessee Health Science Center, analyzed ... 1918, 1957 and 1968 pandemics, as well as ...
Breaking Medicine News(10 mins):Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Study recalculates costs of combination vaccines 2Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:CU researchers discover target for treating dengue fever 2
... ... track essential health care readings such as blood pressure, blood sugar, and weight. Special website ... to their health care providers. , ... Cleveland, OH (PRWEB) June 3, 2009 -- President Obama has made it his pledge ...
... Scientific Experts Gather to Set New Direction and Collaboration ... International Hyperphagia Conference opens this week in Baltimore, MD ... solving hunger amid a global obesity epidemic. This conference ... disciplines from around the world to discuss developments and ...
... to reduce post-op pain and scarring , WEDNESDAY, ... technique shows promise in procedures such as weight-loss ... studies. , The technique, called Natural Orifice Translumenal ... laparoscopic surgery and offers a much faster recovery ...
... Members Complete Picture of Costs Associated with Medical Procedures ... -- Anthem Blue Cross announced today that ... in the following counties in the state: Ventura, Santa ... San Diego, Imperial County, Orange County, San Joaquin/Valley, North ...
... IMAGINE Software, a leading provider of ... within the IMAGINEradiology(TM) practice management system at IMAGINE,s 2009 ... , , The system received a number ... deployment and maintenance distribution through application virtualization; "I-Connect," ...
... Informatics Solution enables healthcare professionals to more immediately ... information , , WARRENDALE, Pa., June 3 ... an informatics application that enables healthcare professionals to ... radiology patients, contrast injections from nearly anywhere. This ...
Cached Medicine News:Health News:New Health Monitoring and Health Tracking Website, VitalsTracker.com, Helps Health Consumers Organize Important Medical Data 2Health News:First International Conference on Appetite Control Begins This Week 2Health News:Abdominal Surgery May Become Easier for Patients 2Health News:Abdominal Surgery May Become Easier for Patients 3Health News:Anthem Blue Cross in California Provides More Members With Access to Comprehensive Transparency Tool 2Health News:Anthem Blue Cross in California Provides More Members With Access to Comprehensive Transparency Tool 3Health News:IMAGINE Software Unveils Advanced IMAGINEradiology(TM) Features 2Health News:MEDRAD Introduces Manage.Report - Advances Evidence-Based Decision Making 2Health News:MEDRAD Introduces Manage.Report - Advances Evidence-Based Decision Making 3
(Date:1/15/2014)...  According to Millennium Research Group (MRG), the global ... the United States and European transcatheter ... moderately through 2022, with embolization particles representing one ... in drug-eluting beads (DEBs) and radioembolization spheres in ...
(Date:1/15/2014)... 15, 2014 Reportlinker.com announces that ... available in its catalogue: ... for Advanced Drug Delivery Systems -- ... http://www.reportlinker.com/p01941928/Global-Markets-and-Technologies-for-Advanced-Drug-Delivery-Systems----Focus-on-Routes-of-Administration.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ...
(Date:1/14/2014)... North America,s leading business partnering event ... 30 th edition of its annual conference at the ... 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ) ... specialty chemical companies will take part in the conference, which ...
Breaking Medicine Technology:US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2
... Like our coat apron, weight is ... hours of comfortable wear without fatigue. ... movement, our front closing special procedure ... "Velcro closures that make it a ...
... Aprons are the result of a technologically ... x-ray aprons. Constructed with a wear resistant, ... the Lead Free aprons exhibit the same ... Each apron weighs approximately 50% less than ...
... is the first objective measurement for ... peptide (BNP) ,Cardiac hormone produced by ... ventricular volume expansion and pressure overload. ... and diastolic dysfunction. The Triage BNP ...
... The Magnetom C! system features 270 accessibility ... with the smallest pole diameter available (54 ... of up to four coils, increased patient ... field strength is 0.35 Tesla. , ,The ...
Medicine Products: