Navigation Links
Brown chemists create cancer-detecting nanoparticles
Date:5/27/2008

PROVIDENCE, R.I. [Brown University] Magnetic resonance imaging (MRI) can be a doctor's best friend for detecting a tumor in the body without resorting to surgery. MRI scans use pulses of magnetic waves and gauge the return signals to identify different types of tissue in the body, distinguishing bone from muscle, fluids from solids, and so on.

Scientists have found that magnetic nanoparticles can be especially helpful in locating cancerous cell clusters during MRI scans. Like teeny guide missiles, the nanoparticles seek out tumor cells and attach themselves to them. Once the nanoparticles bind themselves to these cancer cells, the particles operate like radio transmitters, greatly aiding the MRI's detection capability.

Now, Brown University chemist Shouheng Sun and a team of researchers have created the smallest magnetic nanoparticles to date that can be employed on such seek-and-find missions. With a thinner coating, the particles also emit a stronger signal for the MRI to detect.

The results have been published online this week in the Journal of the American Chemical Society. Brown graduates students Jin Xie, Chenjie Xu and Sheng Peng collaborated on the research, along with Professor Xiaoyuan Chen and his associates from Stanford University.

The team created peptide-coated iron oxide nanoparticles particles billionths of a meter in size. The researchers injected the particles into mice and tested their ability to locate a brain tumor cell called U87MG. Sun and his collaborators concentrated specifically on the nanoparticle's size and the thickness of the peptide coating, which ensures the nanoparticle attaches to the tumor cell.

Size is important because the trick is to create a nanoparticle that is small enough to navigate through the bloodstream and reach the diseased area. Bigger particles tend to stack up, creating the circulatory system's version of a traffic jam. Sun's team developed a nanoparticle that
'/>"/>

Contact: Richard Lewis
richard_lewis@brown.edu
401-863-3766
Brown University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Dr. Michael Brownlee receives JDRF Rumbough Award for Scientific Excellence
2. FDA Approves Health Claim for Brown Rice
3. Dr. Lance H. Brown President-Elect of Dermatologic Society of Greater New York Fights Misconceptions About Sun Protection and Skin Care in Support of Skin Cancer Awareness Month - May
4. Brown & Toland Announces 2007 Financial Results
5. Shannon Brownlee, Author of Overtreated, to Keynote at Defined Healths 8th Annual Therapeutic Insight Conference
6. Actor Rob Brown Rushes to Gain Ground Against Blood Cancer
7. Foundation Radiology Group and Brownsville Tri-County Hospital Sign Long-Term Contract for Diagnostic Imaging Services
8. Local VA Performers Hold February 15 Benefit to Reduce $10,000 in Medical Bills for Former VCU Student Kellie Brown
9. Bobbi Brown Cosmetics Creates Limited-Edition Lip Palette in Partnership with The Heart Truths Red Dress Collection 2008 Fashion Show
10. Bobbi Brown Cosmetics Creates Limited-Edition Red Lip Palette in Partnership With The Heart Truths 2008 Red Dress Collection
11. Senator Sam Brownback and Rep. Chris Smith to Speak at Blogs for Life
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brown chemists create cancer-detecting nanoparticles
(Date:7/13/2014)... a well-known casket manufacturer from China, has announced its newest ... executive officer has announced a new promotion for its funeral ... prices, from 15 to 26 percent off. , “As far ... in the current market. We are excited to release the ... high quality products for sale. Many of our clients are ...
(Date:7/13/2014)... Advanced boilers are preferred over conventional boilers ... fuels, produce high-capacity power, emit fewer pollutants, and ... and climate change concerns, many countries have implemented ... and pollutants coming from fossilfuel-based power plants.North America ... boilers market., The global power rental market is ...
(Date:7/13/2014)... Serena Gordon HealthDay Reporter ... new type of sensor for people with diabetes is being ... instead of blood, researchers report. Scientists at Brown University ... using artificial saliva. It uses light, metal and a special ... "Everybody knows that diabetics have to prick their fingers to ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Max ... Famer, Chris Mullin, will be the featured guest at ... 26th in Puerto Rico. Attendees will learn about ... participate in two exhibition basketball games and perform in ... supplier of health- and energy-boosting supplements , has ...
(Date:7/13/2014)... decreased ability to identify odors might indicate the ... examinations of the eye could indicate the build-up ... the brain, according to the results of four ... International Conference 2014 (AAIC 2014) in Copenhagen. , ... to identify odors was significantly associated with loss ...
Breaking Medicine News(10 mins):Health News:Cheap Oak Caskets Recently Unveiled By China Casket Manufacturer MillionaireCasket.com 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 3Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 2Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 2Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 4Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7
... with thousands of,herb-loving individuals, organizations and businesses across ... tomorrow, Oct. 13. The company will,continue to celebrate ... free 28-ct Mega Men(R) or Women,s Ultra Mega(R) ... National Herb Day recognizes the importance of ...
... the solution to providing ... STORRS, Conn., Oct. 12 A new report released,today ... low health,literacy to the United States economy is in the ... report, Low Health Literacy:,Implications for National Health Policy, the savings ...
... (Nasdaq: ARAY ), a global leader in the ... for its first quarter fiscal,year 2008, ending September 29, ... A conference call to review the results will ... be hosted by Euan S. Thomson, Ph.D., president and,chief ...
... might fight deadly pulmonary disease, experts say , , FRIDAY, Oct. ... cholesterol also slow the lung function loss that inevitably occurs ... researchers report. , The Harvard study included a group of ... at least twice between 1995 and 2005. , Those who ...
... be good for lowering cholesterol and maybe even fighting ... appear to slow decline in lung function in the ... in Boston, it may be statins anti-inflammatory and antioxidant ... were published in the second issue for October in ...
... Feeds the Soul and Whets the Appetite, RALEIGH, ... this weight-loss support group turned relay team, wondered what,their ... would be. Maria,Fernandez and the members of TeamGDT thought ... for the Cure", was a great answer,to not only ...
Cached Medicine News:Health News:GNC Honors Herb Day Tomorrow (and All Month Long) 2Health News:New Report Estimates Cost of Low Health Literacy Between $106 - $236 Billion Annually 2Health News:New Report Estimates Cost of Low Health Literacy Between $106 - $236 Billion Annually 3Health News:Accuray Incorporated to Report First Quarter Fiscal Year 2008 Financial Results 2Health News:Anti-Cholesterol Drugs Help Prevent Lung Decline 2Health News:Statins reduce loss of function, keeping old lungs young - even in smokers 2Health News:Good Food. Good Friends. Great Cause. 2
(Date:7/10/2014)... CLEVELAND , July 10, 2014  The U.S. ... a three-year grant to University Hospitals (UH) Case Medical ... a new national model aimed at improving care for ... Oncology Care," the project will test a unique model ... patients with late-stage disease, significant comorbidities, or demonstrated need ...
(Date:7/10/2014)... INC. (NYSE: RMD ) today announced that it ... 30, 2014 results on Thursday, July 31, 2014, after the ... ResMed,s results will be issued after 1:00 p.m. US Pacific ... operating results and future outlook. The earnings call ... and the live webcast of the call can be accessed ...
(Date:7/10/2014)...  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... the sale to Galderma of all rights to Restylane, ... Valeant for $1.4 billion in cash, pursuant to the ... its acquisition of Galderma. "We are ... a company that is firmly committed to the aesthetic ...
Breaking Medicine Technology:University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2
... , Some form of electronic hematology analyzer is ... blood cell count is usually the first screening test ... infection, and monitor cancer patients during the course of ... this workhorse device, and surprising to learn its origins., ...
... ,Medical conventions are challenged every day. Already in ... and the gold standard in breast cancer treatment ... the latest casualty of medical innovation., ,For years, ... of high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein ...
Cached Medicine Technology:Hematology Analyzers Simple, Sophisticated Technology Serving All Patients 2Hematology Analyzers Simple, Sophisticated Technology Serving All Patients 3Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal 2Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal 3
... Eppendorf expands its line of ... easy-to-use microcentrifuge features a certified aerosol-tight ... bowl design to reduce noise., ,Model ... offering optional rotors to accommodate microcentrifuge ...
The new BioZ Dx incorporates the world's most advanced impedance cardiography (ICG) technology and powerful reporting features to quickly and easily provide noninvasive hemodynamic parameters....
... Varicella-Zoster (VZ) test system is ... semi-quantitative detection of VZ IgG ... the indirect fluorescent antibody (IFA) ... or confirm a recent infection ...
Inquire...
Medicine Products: