Navigation Links
Brown chemists create cancer-detecting nanoparticles
Date:5/27/2008

PROVIDENCE, R.I. [Brown University] Magnetic resonance imaging (MRI) can be a doctor's best friend for detecting a tumor in the body without resorting to surgery. MRI scans use pulses of magnetic waves and gauge the return signals to identify different types of tissue in the body, distinguishing bone from muscle, fluids from solids, and so on.

Scientists have found that magnetic nanoparticles can be especially helpful in locating cancerous cell clusters during MRI scans. Like teeny guide missiles, the nanoparticles seek out tumor cells and attach themselves to them. Once the nanoparticles bind themselves to these cancer cells, the particles operate like radio transmitters, greatly aiding the MRI's detection capability.

Now, Brown University chemist Shouheng Sun and a team of researchers have created the smallest magnetic nanoparticles to date that can be employed on such seek-and-find missions. With a thinner coating, the particles also emit a stronger signal for the MRI to detect.

The results have been published online this week in the Journal of the American Chemical Society. Brown graduates students Jin Xie, Chenjie Xu and Sheng Peng collaborated on the research, along with Professor Xiaoyuan Chen and his associates from Stanford University.

The team created peptide-coated iron oxide nanoparticles particles billionths of a meter in size. The researchers injected the particles into mice and tested their ability to locate a brain tumor cell called U87MG. Sun and his collaborators concentrated specifically on the nanoparticle's size and the thickness of the peptide coating, which ensures the nanoparticle attaches to the tumor cell.

Size is important because the trick is to create a nanoparticle that is small enough to navigate through the bloodstream and reach the diseased area. Bigger particles tend to stack up, creating the circulatory system's version of a traffic jam. Sun's team developed a nanoparticle that
'/>"/>

Contact: Richard Lewis
richard_lewis@brown.edu
401-863-3766
Brown University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Dr. Michael Brownlee receives JDRF Rumbough Award for Scientific Excellence
2. FDA Approves Health Claim for Brown Rice
3. Dr. Lance H. Brown President-Elect of Dermatologic Society of Greater New York Fights Misconceptions About Sun Protection and Skin Care in Support of Skin Cancer Awareness Month - May
4. Brown & Toland Announces 2007 Financial Results
5. Shannon Brownlee, Author of Overtreated, to Keynote at Defined Healths 8th Annual Therapeutic Insight Conference
6. Actor Rob Brown Rushes to Gain Ground Against Blood Cancer
7. Foundation Radiology Group and Brownsville Tri-County Hospital Sign Long-Term Contract for Diagnostic Imaging Services
8. Local VA Performers Hold February 15 Benefit to Reduce $10,000 in Medical Bills for Former VCU Student Kellie Brown
9. Bobbi Brown Cosmetics Creates Limited-Edition Lip Palette in Partnership with The Heart Truths Red Dress Collection 2008 Fashion Show
10. Bobbi Brown Cosmetics Creates Limited-Edition Red Lip Palette in Partnership With The Heart Truths 2008 Red Dress Collection
11. Senator Sam Brownback and Rep. Chris Smith to Speak at Blogs for Life
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brown chemists create cancer-detecting nanoparticles
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 IsoComforter, Inc. ... therapy machine with patented IsoTube design to treat specific body ... introduced the most progressive and easy to use patented cold ... post-operative and sports related orthopedic and muscle injuries. IsoComforter ...
(Date:1/22/2015)... Payday lending practices in four southern states worsen ... to the states that permit them, according to a ... Race and Wealth. , While they generate hundreds of ... the same time substantially depress economic activity, according to ...
(Date:1/22/2015)... As interest in the value of spiritual support as ... Rev. Eric J. Hall , president and CEO of the ... the keynote speaker on January 27 at an international summit ... The conference, “Hope and Resilience: Innovative and Interdisciplinary Spiritual Care,” ...
(Date:1/22/2015)... January 22, 2015 Compare-autoinsurance.org has released a new ... by an auto insurance policy . , Some types ... Clients should check the newly released blog post to see if ... and dangerously damaged vehicles are some of the cars that cannot ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Step into ... at the Science Museum of Virginia. Wicked Plants, the ... Wicked Plants unearths 75 poisonous, carnivorous and diabolical plants ... each room to uncover the biochemical, physical and neurological ...
Breaking Medicine News(10 mins):Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... GLASSBORO, N.J., Aug. 25 Getting a firmer, healthier, better-looking body -- in ... a fitness plan that will truly help you reach your personal goals. , ... , , , An ... you will dedicate to achieving your fitness goals and stick with it! , ...
... , Study Suggests Division, Ambivalence and Hesitancy ... ANN ARBOR, Mich., Aug. 25 Americans lack confidence that healthcare ... to a survey released today by the Thomson Reuters. , ... healthcare reform, addresses a wide range of issues including the cost ...
... Most OTC hemorrhoid ... your hemorrhoids faster. , ... York, NY (PRWEB) August 26, 2009 -- Many drug companies desperately do not want revealed ... damage. "Steroid creams in particular may cause permanent damage or ulceration of perianal skin," states ...
... , , Updated Report ... , , LANDOVER, Md., Aug. 25 ... conditions, the school-house is a focal point for managing their diseases. ... and Allergy Foundation of America (AAFA) has released a report assessing ...
... ONCOLOGY: Human breast cancer hit for six: key role for ... and colleagues, at the University of Colorado School of Medicine, ... mouse models and analysis of human cells, implicating the protein ... that plays a central role in development, is not expressed ...
... , , OMAHA, ... its private equity sponsor, Diamond Castle Holdings and the Company,s Management ... debt and renegotiated favorable new terms and conditions with its banking ... As a result of this transaction, overall debt for YORK ...
Cached Medicine News:Health News:Why Weight for a Better Body? 2Health News:Thomson Reuters Survey: Americans Skeptical that Healthcare Reform Will Improve Quality or Affordability 2Health News:Thomson Reuters Survey: Americans Skeptical that Healthcare Reform Will Improve Quality or Affordability 3Health News:Introducing anuleaf AD, a New FDA-Approved Hemorrhoid Treatment 2Health News:Deja Vu for Six States on Annual Asthma & Allergy Honor Roll 2Health News:Deja Vu for Six States on Annual Asthma & Allergy Honor Roll 3Health News:JCI table of contents: Aug. 24, 2009 2Health News:JCI table of contents: Aug. 24, 2009 3Health News:JCI table of contents: Aug. 24, 2009 4Health News:JCI table of contents: Aug. 24, 2009 5Health News:JCI table of contents: Aug. 24, 2009 6Health News:YORK Label Announces Continued Investment in the Company 2
(Date:1/23/2015)... 2015  HyGreen, Inc., a leader in hand hygiene monitoring, ... Medical, a subsidiary of Ascendis Health Limited, in ... year, hundreds of millions of patients around the world ... transmitted from patient to patient via the unwashed hands ...
(Date:1/23/2015)... Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC Bulletin ... a Preliminary Proxy Statement, Schedule 14A, with the U.S. Securities ... update for shareholders detailing why a "YES" vote to increase ... Shareholders, As we reflect upon the 2014 fiscal ...
(Date:1/23/2015)... 2015 Gem Pharmaceuticals announced today that the initial ... the Company,s Phase 2 clinical trial.  This open-label study ... compound, GPX-150 (an investigational medication), in approximately 30 adults ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
Breaking Medicine Technology:HyGreen Partners with RCA Medical in Johannesburg, South Africa 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2
Foley Catheters (Latex) 2-Way...
Silicone Elastomer-Coated Latex Foley Catheters 3-Way...
Silicone Foley Catheters 2-Way (Pediatric)...
Midstream Catch Kits...
Medicine Products: