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Brookhaven Lab and Hybridyne Imaging Technologies Inc., win R&D 100 award
Date:7/23/2009

not easily be distinguished by ultrasound, and fibrous tissues can be mistakenly identified as tumors if patients have had radiation treatment of the prostate previously. Traditional nuclear imaging systems produce lower-resolution images and are less efficient than Brookhaven's compact digital camera. Also, the detectors in current systems are too large to be used in trans-rectal probes.

In contrast, the new cadmium zinc telluride (CZT)-based gamma camera is small enough for trans-rectal prostate cancer diagnosis, after the patient is injected with a tracer radiopharmaceutical. The high-resolution CZT detector is the cutting-edge technology that drives the novel system. Using this new technology, the working distance between the imaging system and the prostate gland is minimized, allowing urologists to obtain better images with a smaller amount of injected radioactive tracer, compared to conventional nuclear medical systems.

"This project has been a great opportunity to take gamma-ray detector technology originally developed for national security and apply it toward important societal goals in the area of cancer diagnosis and treatment," said Ralph James, a senior physicist at Brookhaven who is the Laboratory's principal co-inventor of the technology together with Brookhaven associate scientist Yonggang Cui.

Cui added, "The CZT material combines the best aspects of conventional nuclear imaging detectors while minimizing their weaknesses. Our experience in detector development and electronics design has been critical in delivering this high performance system in a very compact package at a competitive cost."

Although the CZT-based system was designed to reveal prostate cancer, it can be modified for imaging other cancers, such as cervical, uterine, colorectal and breast cancers. It can also be optimized for surgical use as a probe to guide the removal of cancerous tumors while minimizing damage to surrounding healthy tissues.'/>"/>

Contact: Diane Greenberg
greenb@bnl.gov
631-344-2347
DOE/Brookhaven National Laboratory
Source:Eurekalert

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