Navigation Links
Broccoli Sprout Extract Hinders Bladder Cancer Development
Date:2/28/2008

Rats given concentrated dose had risk of growths cut in half, study says

THURSDAY, Feb. 28 (HealthDay News) -- A concentrated extract of freeze-dried broccoli sprouts reduced bladder tumor development by more than half in laboratory rats, according to a new study.

Researchers said the finding supports human epidemiologic studies indicating that eating broccoli and other cruciferous vegetables is associated with a lower risk of bladder cancer.

"Although this is an animal study, it provides potent evidence that eating vegetables is beneficial in bladder cancer prevention," senior investigator Dr. Yuesheng Zhang, a professor of oncology at Roswell Park Cancer Institute, said in a prepared statement.

It's believed that the protective effect of broccoli and other cruciferous vegetables -- such as cabbage, kale, and collard greens -- is at least partly due to isothyiocyanates (ITCs), a group of phytochemicals with anti-cancer properties.

"The bladder is particularly responsive to this group of natural chemicals," Zhang said.

He and his colleagues tested the freeze-dried broccoli sprout extract in rats given a chemical that induces bladder cancer. One group of rats did not receive the extract, while two other groups of rats were given either a low or high dose of the extract in their food, beginning two weeks before they received the cancer-causing chemical.

An average of about two tumors developed in 96 percent of the rats that didn't receive the extract, compared to an average of 1.39 tumors in 74 percent of the rats that received a low dose of the extract, and an average of .46 tumors in 38 percent of the rats that received a high dose of the extract.

The findings were published in the March 1 issue of the journal Cancer Research.

Broccoli sprouts have about 30 times more ITCs than mature broccoli, and the sprout extract used in this study has about 600 times as much. But Zhang said humans at risk for bladder cancer likely wouldn't have to eat large amounts of broccoli sprouts to achieve protective effects.

"Epidemiologic studies have shown that dietary ITCs and cruciferous vegetable intake are inversely associated with bladder cancer risk in humans. It is possible that ITC doses much lower than those given to the rats in this study may be adequate for bladder cancer prevention," he said.

More information

The American Urological Association has more about bladder cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, Feb. 28, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Blackberries, Broccoli Sprouts Battle Cancer
2. Broccoli May Help Fight Skin Cancer
3. Broccoli sprout-derived extract protects against ultraviolet radiation
4. NutraCea Forms Joint Ventures With HerbalScience to Develop Nutraceutical Extracts and Pharmaceutical Chemistries From Stabilized Rice Bran
5. Metabothin B56 with Ephedra Extract Now Available
6. Green Tea, Fruit Extracts Touted as Potential Cancer Fighters
7. Herbal extract found to increase lifespan
8. Extracts of catfish caught in polluted waters cause breast cancer cells to multiply
9. New study: pine bark extract boosts nitric oxide production
10. New study: Pine bark extract reduces ADHD symptoms in children
11. UT Southwestern surgeons complete North Texas first single-incision gallbladder removal
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broccoli Sprout Extract Hinders Bladder Cancer Development
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... 2017 , ... Lori R. Somekh, founder of the Law Office of ... elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain ... to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical ... innovative solutions for injectable drug administration, today shared the ... ID Adapter for improving the intradermal administration of polio ... Skin Vaccination Summit in May 2017 by Dr. ... Polio Department, World Health Organization (WHO), and recently published ...
(Date:10/4/2017)... 4, 2017 OBP Medical , ... medical devices, today announced regulatory approval from ... (or Agência Nacional de Vigilância Sanitária (ANVISA)) to ... surgical retractor with integrated LED light source and ... and exposure of a tissue pocket or cavity ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: