Navigation Links
Broccoli Sprout Extract Hinders Bladder Cancer Development
Date:2/28/2008

Rats given concentrated dose had risk of growths cut in half, study says

THURSDAY, Feb. 28 (HealthDay News) -- A concentrated extract of freeze-dried broccoli sprouts reduced bladder tumor development by more than half in laboratory rats, according to a new study.

Researchers said the finding supports human epidemiologic studies indicating that eating broccoli and other cruciferous vegetables is associated with a lower risk of bladder cancer.

"Although this is an animal study, it provides potent evidence that eating vegetables is beneficial in bladder cancer prevention," senior investigator Dr. Yuesheng Zhang, a professor of oncology at Roswell Park Cancer Institute, said in a prepared statement.

It's believed that the protective effect of broccoli and other cruciferous vegetables -- such as cabbage, kale, and collard greens -- is at least partly due to isothyiocyanates (ITCs), a group of phytochemicals with anti-cancer properties.

"The bladder is particularly responsive to this group of natural chemicals," Zhang said.

He and his colleagues tested the freeze-dried broccoli sprout extract in rats given a chemical that induces bladder cancer. One group of rats did not receive the extract, while two other groups of rats were given either a low or high dose of the extract in their food, beginning two weeks before they received the cancer-causing chemical.

An average of about two tumors developed in 96 percent of the rats that didn't receive the extract, compared to an average of 1.39 tumors in 74 percent of the rats that received a low dose of the extract, and an average of .46 tumors in 38 percent of the rats that received a high dose of the extract.

The findings were published in the March 1 issue of the journal Cancer Research.

Broccoli sprouts have about 30 times more ITCs than mature broccoli, and the sprout extract used in this study has about 600 times as much. But Zhang said humans at risk for bladder cancer likely wouldn't have to eat large amounts of broccoli sprouts to achieve protective effects.

"Epidemiologic studies have shown that dietary ITCs and cruciferous vegetable intake are inversely associated with bladder cancer risk in humans. It is possible that ITC doses much lower than those given to the rats in this study may be adequate for bladder cancer prevention," he said.

More information

The American Urological Association has more about bladder cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, Feb. 28, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Blackberries, Broccoli Sprouts Battle Cancer
2. Broccoli May Help Fight Skin Cancer
3. Broccoli sprout-derived extract protects against ultraviolet radiation
4. NutraCea Forms Joint Ventures With HerbalScience to Develop Nutraceutical Extracts and Pharmaceutical Chemistries From Stabilized Rice Bran
5. Metabothin B56 with Ephedra Extract Now Available
6. Green Tea, Fruit Extracts Touted as Potential Cancer Fighters
7. Herbal extract found to increase lifespan
8. Extracts of catfish caught in polluted waters cause breast cancer cells to multiply
9. New study: pine bark extract boosts nitric oxide production
10. New study: Pine bark extract reduces ADHD symptoms in children
11. UT Southwestern surgeons complete North Texas first single-incision gallbladder removal
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broccoli Sprout Extract Hinders Bladder Cancer Development
(Date:2/5/2016)... ... ... Love is in the air at King Kullen! The local grocer is ... staple for Valentine’s Day is a must-have, and can be picked up with all ... are long-stem roses available, but also other flower bouquets, elegantly wrapped and ready to ...
(Date:2/5/2016)... ... 05, 2016 , ... The Muscular Dystrophy Association and Sailormen ... the 14th annual “Appetite for a Cure” campaign on Feb. 1 to raise ... related diseases that severely limit strength and mobility. , Now through March ...
(Date:2/5/2016)... Miami, Florida (PRWEB) , ... February 05, 2016 ... ... largest non-profit organization devoted exclusively to funding innovative lymphoma research and serving the ... services – is poised to once again host, Swirl, A Wine Tasting Event ...
(Date:2/5/2016)... ... ... Give To Cure today announced that it is working with ... Cure’s campaign that is crowdfunding clinical trials to help find cures faster for Alzheimer’s ... smart device. In 2015 alone, Venmo processed $7.5 billion in transactions among users. , ...
(Date:2/5/2016)... ... , ... Stuart Bentkover, MD, FACS is thrilled to announce the ... effective tattoo removal today, Dr. Bentkover is the only doctor in Central Massachusetts to ... has been approved by the Food and Drug Administration (FDA) as a safe and ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016 ... addition of the "Global Musculoskeletal Partnering ... company profile to their offering. ... addition of the "Global Musculoskeletal Partnering ... company profile to their offering. ...
(Date:2/5/2016)... Dehaier Medical Systems Ltd. (Nasdaq: ... develops, markets and sells medical devices and wearable ... and international markets, today announced its corporate ... the Company,s resources to develop its mobile health ... focus more on its major businesses. As of ...
(Date:2/5/2016)... Site Profile: --> ... The Speech Recognition People, announced their latest primary healthcare case study ... reduce turnaround times and to save the practice money. ... 2013 Challenge: --> ,- Wirral CCG ,- ... Six doctors ,- Wirral CCG ,- VoicePower client since 2013 ...
Breaking Medicine Technology: