Navigation Links
Broccoli May Ward Off Serious Stomach Ailments
Date:4/6/2009

Results of small study hint at cancer-preventing ability, researcher says

MONDAY, April 6 (HealthDay News) -- Eating 2.5 ounces a day of broccoli sprouts appeared to reduce the risk of stomach ulcers and probably stomach cancer in a Japanese trial.

Gastric cancer thus joins a long list of malignancies for which studies have shown a reduced risk associated with a diet that contains broccoli -- including cancer of the esophagus, bladder, skin and lung, among others.

"I have to be careful about how enthusiastically I state the case," said Jed W. Fahey, the faculty research associate at Johns Hopkins School of Medicine whose research led to the Japanese study. "This was a small trial. But the evidence is all pointing toward broccoli or broccoli sprouts being able to prevent cancer in humans."

The chemical in broccoli responsible for the protective effect is sulforaphane, Fahey said. His group first described it as a potent antibiotic against Helicobacter pylori in 2002. The Japanese study, reported in the April issue of Cancer Prevention Research, was designed to show whether eating broccoli sprouts, which are rich in sulforaphane, resulted in lower levels of H. pylori, a bacterium that is closely associated with the risk of stomach damage and gastric cancer.

The study was done in Japan because the rate of H. pylori infection there is high. Though about 25 percent to 30 percent of Americans are infected, "in Japan there is infection at levels approaching 90 percent because of crowding and poor economic conditions," Fahey said. The bacterium is spread by person-to-person contact.

The study included 48 infected people. Half ate 70 grams a day of broccoli sprouts, and the others ate alfalfa sprouts, which do not contain sulforaphane. After eight weeks, tests showed significantly lower levels of H. pylori infection in those who ate broccoli sprouts, with no reduction among the alfalfa sprout eaters.

"H. pylori is a known carcinogen," Fahey said. "The fact that we were able to reduce the effects of an infectious agent that is also a carcinogen gives us hope that if someone were to eat broccoli sprouts or broccoli regularly, it would reduce levels of H. pylori and, over a period of many years, reduce the chance that they would get that cancer. It is not proven, but the results are highly suggestive."

Fahey is a co-founder of a company licensed by Hopkins to produce broccoli sprouts. He has no equity in the company.

Broccoli and sprouts are both important, said Dr. Steven H. Zeisel, director of the Nutrition Research Institute at the University of North Carolina.

"Specifically, the sprouts before broccoli becomes a plant are rich in sulforaphane," Zeisel said. "It is formed only when broccoli or sprouts are macerated, chewed on. When you break the cell, the chemical is formed."

Sulforaphane then causes the liver to produce an enzyme that is important in deactivating cancer-causing agents, Zeisel said. "People who eat more broccoli tune up their liver and other cells to destroy cancer-causing agents," he said.

Garlic has the same effect, he said, and so "increasing the amount of plants in the diet -- broccoli is good, broccoli sprouts even better -- causes production of a valuable bioactive chemical."

That is good advice, Fahey said, but inevitably some people will try a shortcut, taking a sulforaphane pill rather than eating what's good for them.

"I have come to the resigned conclusion that we will not be able to persuade everybody to change their diet," Fahey said. "A pill would be better than nothing, but that doesn't mean that I'm advocating it or promoting massive pill-taking."

Just two or three ounces a day of cooked broccoli would have a protective effect, he said.

Zeisel added that people who try the pill-taking shortcut might well lose any benefit.

"It's probably a combination of ingredients in the plant that is responsible," he said. "When you try to extract them out to make a pill, it usually doesn't work."

More information

The U.S. National Cancer Institute has information on diet and cancer.



SOURCES: Jed W. Fahey, Sc.D., faculty research assistant, Johns Hopkins School of Medicine, Baltimore; Steven H. Zeisel, M.D., director, Nutrition Research Institute, University of North Carolina, Chapel Hill, N.C.; March 6, 2009, Cancer Prevention Research


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Broccoli may help protect against respiratory conditions like asthma
2. Broccoli compound targets key enzyme in late-stage cancer
3. Broccoli Compound May Help COPD Patients
4. Broccoli Sprout Extract Hinders Bladder Cancer Development
5. Blackberries, Broccoli Sprouts Battle Cancer
6. Broccoli May Help Fight Skin Cancer
7. Broccoli sprout-derived extract protects against ultraviolet radiation
8. Council for American Medical Innovation Applauds President Obama for Calling for Serious Investments in Science and Technology
9. New study finds daily drinking is biggest risk factor in serious liver disease
10. Trial Vaccine May Protect Against Serious Viral Infection
11. Drive Alert, Arrive Safe - Better Sleep Could Cut Serious Road Accidents By A Third
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broccoli May Ward Off Serious Stomach Ailments
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from ... at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center ... care topics including advance care planning, healthcare costs and patient and family engagement. ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... ... ... crisis. Her son James, eight, was out of control. Prone to extreme mood shifts and ... him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife on ... say he was going to kill them. If we were driving on the freeway, ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SOUTH SAN FRANCISCO, Calif. , June 24, ... GBT ), a biopharmaceutical company developing novel ... with significant unmet needs, today announced the closing ... 6,400,000 shares of common stock, at the public ... the shares in the offering were offered by ...
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
(Date:6/24/2016)... ALEXANDRIA, Va. , June 24, 2016 ... a set of recommendations that would allow ... information (HCEI) with entities that make formulary and coverage ... determine the "value" of new medicines. The ... that does not appear on the drug label, a ...
Breaking Medicine Technology: