Navigation Links
Broccoli May Ward Off Serious Stomach Ailments
Date:4/6/2009

Results of small study hint at cancer-preventing ability, researcher says

MONDAY, April 6 (HealthDay News) -- Eating 2.5 ounces a day of broccoli sprouts appeared to reduce the risk of stomach ulcers and probably stomach cancer in a Japanese trial.

Gastric cancer thus joins a long list of malignancies for which studies have shown a reduced risk associated with a diet that contains broccoli -- including cancer of the esophagus, bladder, skin and lung, among others.

"I have to be careful about how enthusiastically I state the case," said Jed W. Fahey, the faculty research associate at Johns Hopkins School of Medicine whose research led to the Japanese study. "This was a small trial. But the evidence is all pointing toward broccoli or broccoli sprouts being able to prevent cancer in humans."

The chemical in broccoli responsible for the protective effect is sulforaphane, Fahey said. His group first described it as a potent antibiotic against Helicobacter pylori in 2002. The Japanese study, reported in the April issue of Cancer Prevention Research, was designed to show whether eating broccoli sprouts, which are rich in sulforaphane, resulted in lower levels of H. pylori, a bacterium that is closely associated with the risk of stomach damage and gastric cancer.

The study was done in Japan because the rate of H. pylori infection there is high. Though about 25 percent to 30 percent of Americans are infected, "in Japan there is infection at levels approaching 90 percent because of crowding and poor economic conditions," Fahey said. The bacterium is spread by person-to-person contact.

The study included 48 infected people. Half ate 70 grams a day of broccoli sprouts, and the others ate alfalfa sprouts, which do not contain sulforaphane. After eight weeks, tests showed significantly lower levels of H. pylori infection in those who ate broccoli sprouts, with no reduction among the alfalfa sprout eaters.

"H. pylori is a known carcinogen," Fahey said. "The fact that we were able to reduce the effects of an infectious agent that is also a carcinogen gives us hope that if someone were to eat broccoli sprouts or broccoli regularly, it would reduce levels of H. pylori and, over a period of many years, reduce the chance that they would get that cancer. It is not proven, but the results are highly suggestive."

Fahey is a co-founder of a company licensed by Hopkins to produce broccoli sprouts. He has no equity in the company.

Broccoli and sprouts are both important, said Dr. Steven H. Zeisel, director of the Nutrition Research Institute at the University of North Carolina.

"Specifically, the sprouts before broccoli becomes a plant are rich in sulforaphane," Zeisel said. "It is formed only when broccoli or sprouts are macerated, chewed on. When you break the cell, the chemical is formed."

Sulforaphane then causes the liver to produce an enzyme that is important in deactivating cancer-causing agents, Zeisel said. "People who eat more broccoli tune up their liver and other cells to destroy cancer-causing agents," he said.

Garlic has the same effect, he said, and so "increasing the amount of plants in the diet -- broccoli is good, broccoli sprouts even better -- causes production of a valuable bioactive chemical."

That is good advice, Fahey said, but inevitably some people will try a shortcut, taking a sulforaphane pill rather than eating what's good for them.

"I have come to the resigned conclusion that we will not be able to persuade everybody to change their diet," Fahey said. "A pill would be better than nothing, but that doesn't mean that I'm advocating it or promoting massive pill-taking."

Just two or three ounces a day of cooked broccoli would have a protective effect, he said.

Zeisel added that people who try the pill-taking shortcut might well lose any benefit.

"It's probably a combination of ingredients in the plant that is responsible," he said. "When you try to extract them out to make a pill, it usually doesn't work."

More information

The U.S. National Cancer Institute has information on diet and cancer.



SOURCES: Jed W. Fahey, Sc.D., faculty research assistant, Johns Hopkins School of Medicine, Baltimore; Steven H. Zeisel, M.D., director, Nutrition Research Institute, University of North Carolina, Chapel Hill, N.C.; March 6, 2009, Cancer Prevention Research


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Broccoli may help protect against respiratory conditions like asthma
2. Broccoli compound targets key enzyme in late-stage cancer
3. Broccoli Compound May Help COPD Patients
4. Broccoli Sprout Extract Hinders Bladder Cancer Development
5. Blackberries, Broccoli Sprouts Battle Cancer
6. Broccoli May Help Fight Skin Cancer
7. Broccoli sprout-derived extract protects against ultraviolet radiation
8. Council for American Medical Innovation Applauds President Obama for Calling for Serious Investments in Science and Technology
9. New study finds daily drinking is biggest risk factor in serious liver disease
10. Trial Vaccine May Protect Against Serious Viral Infection
11. Drive Alert, Arrive Safe - Better Sleep Could Cut Serious Road Accidents By A Third
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broccoli May Ward Off Serious Stomach Ailments
(Date:12/4/2016)... , ... December 03, 2016 , ... While James Earl ... serving as host for in a show called "Front Page". One of the forthcoming ... years, breast cancer rates have plummeted in large part due to early detection. Like ...
(Date:12/4/2016)... Washington DC (PRWEB) , ... December 04, 2016 , ... ... Environmental, one of the most certified and experienced Indoor Air Quality Companies in VA, ... Assessment and Remediation Regulations. , The new mold law in the district ...
(Date:12/2/2016)... ... December 02, 2016 , ... On Dec. 2, 2016, CURE® magazine ... San Diego honoring the 2016 MPN Heroes—eight individuals who have made a difference in ... and beyond the standard of care, demonstrating leadership within the MPN community and/or a ...
(Date:12/2/2016)... ... 2016 , ... Center for Autism and Related Disorders (CARD) Portland today announced ... disorder (ASD) and other developmental disabilities. The group, which is being launched with the ... the opportunity to share stories and advice, seek help, and continue their education on ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... California, will be included in the 2016 “Guide to America’s Top Plastic Surgeons” ... on the amalgamation of their education, experience, and professional associations. , One ...
Breaking Medicine News(10 mins):
(Date:12/4/2016)... 3, 2016 Johnson & Weaver, LLP announces that ... of Zimmer Biomet Holdings, Inc. (NYSE: ZBH ) ... 31, 2016 (the "Class Period"). Zimmer Biomet provides ... orthopaedic reconstructive products, such as knee and hip reconstructive products. ... , , ...
(Date:12/4/2016)...   Pairnomix, LLC, a genetic research company and ... the White House, today announced that findings from its first ... candidate therapies for a patient with epileptic encephalopathy caused by ... at the 70 th Annual Meeting of the ... , December 2-6, 2016.  Pairnomix, unique process involves ...
(Date:12/4/2016)...  Results from the Phase II SUSTAIN study show ... the median annual rate of sickle cell-related pain crises ... p=0.010) in patients with or without hydroxyurea therapy 1 ... featured in the official press briefing at the 58 ... and presented during the Plenary Scientific Session tomorrow (Abstract ...
Breaking Medicine Technology: