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Broader organ sharing won't harm liver transplant recipients
Date:8/14/2014

New research shows that broader sharing of deceased donor livers will not significantly increase cold ischemia time (CIT)the time the liver is in a cooled state outside the donor suggesting that this is not a barrier to broader sharing of organs. However, findings published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, do indicate that broader sharing of organs will significantly increase the percentage of donor organs that are transported by flying rather than driving.

The ongoing shortage of livers available for transplantation continues to be a concern in the U.S., impacting some geographic areas more than others. Recent allocation policy changes seek to address organ shortages and reduce geographic disparity. Livers are offered at the regional level first to candidates most at risk of death (status 1) and those with Model for End-Stage Liver Disease (MELD) a score of 35 or more before being offered to local wait list candidates.

"Shortages and geographic inequity of organs available for transplant have required the liver transplant community to reassess the allocation policy in the U.S., and even broader sharing of organs may be needed," explains Dr. Sommer Gentry with the United States Naval Academy in Annapolis, Md. "One concern with broader sharing is that transport times may increase and affect CIT, which could impair organ quality."

For the present study, the team first surveyed all organ procurement organizations to verify use of helicopters for transporting liver allografts, if a central facility was used to recover the organ, and at what distance the mode of transportation changed from driving to flying. Using the Scientific Registry of Transplant Recipients, researchers identified 111 centers that performed at least one adult liver transplant along with hospitals that recovered at least one of the 1284 de
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Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert  

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