Navigation Links
Broad-Spectrum Cervical Cancer Vaccine Shows Promise
Date:5/26/2009

Tests in animals get good results against more types of HPV, study finds

TUESDAY, May 26 (HealthDay News) -- An investigational broad-spectrum cervical cancer vaccine induced strong immune responses in mice and rabbits, and protected them against human papillomavirus (HPV) type 16 for four months, new research has found.

Current HPV L1-based vaccines provide almost 100 percent protection against the two types of HPV that cause 70 percent of all cervical cancer cases worldwide, but they are expensive and offer only limited protection against other HPV types that cause cancer, according to the researchers. The new vaccine may help cover that gap in protection, they noted.

When the candidate vaccine was used with a substance such as alum to stimulate immune response, the animals were protected against infection by HPV type 16, the study found.

"Clinical studies are warranted" to assess the safety of these types of vaccines, wrote Richard Roden, of the Johns Hopkins University in Baltimore, and colleagues. If this new type of vaccine proves effective, "its simpler manufacturing process could make the local production of such a vaccine highly feasible, which might achieve the goal of producing it at sustainable prices in emerging countries and lead to its widespread implementation in the developing world," the researchers said.

The study appears online Tuesday in the Journal of the National Cancer Institute.

A broad-spectrum HPV vaccine could solve the shortcomings of current vaccines -- they're too expensive to be used in much of the world and they don't protect against enough HPV types -- Dr. F. Xavier Bosch, of the Catalan Institute of Oncology in Barcelona, Spain, wrote in an accompanying editorial.

The results of this study "open the door to a novel family of second generation HPV vaccines with significant potential value in the public health horizon. As soon as appropriate, Phase 1 trials in humans should be initiated," Bosch wrote.

More information

The U.S. Food and Drug Administration has more about HPV.



-- Robert Preidt



SOURCE: Journal of the National Cancer Institute, news release, May 26, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. A Broad-Spectrum Antibiotic with Activity Against MRSA and Pseudomonas Aeruginosa Would Earn a Higher Patient Share in the U.S. than in Europe for the Treatment of Hospital-Acquired Pneumonia
2. Life Spine(R) Announces Nationwide Market Introduction of KINETIC(R)-SL Dynamic Anterior Cervical Plating System
3. Women with previous abnormal cervical cells at higher risk for recurrence and invasive cancer
4. Dont Lower Age for Cervical Cancer Test, Study Urges
5. NuVasive Announces Acquisition of Cervical Total Disc Replacement Device
6. Womens Health Advocates To Moms: We Can Beat Cervical Cancer!
7. Human papillomavirus genotype distribution in New Mexico cervical cancers
8. Womens Integrative Health Encinitas OB/GYN Selects LUMA Cervical Imaging System
9. MRI and PET/CT improve cervical cancer patients chances for optimal treatment
10. Incidence rates of cervical cancer linked to deprivation
11. LUMA Cervical Imaging System Installed in Edina at Minnesota Gynecology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broad-Spectrum Cervical Cancer Vaccine Shows Promise
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... cutting edge technology to revolutionize the emergency ambulance transport experience for the millions ... aware of how Uber has disrupted the taxi industry through the use of ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health ... of their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards ... at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
Breaking Medicine Technology: