Navigation Links
Broad-Spectrum Cervical Cancer Vaccine Shows Promise
Date:5/26/2009

Tests in animals get good results against more types of HPV, study finds

TUESDAY, May 26 (HealthDay News) -- An investigational broad-spectrum cervical cancer vaccine induced strong immune responses in mice and rabbits, and protected them against human papillomavirus (HPV) type 16 for four months, new research has found.

Current HPV L1-based vaccines provide almost 100 percent protection against the two types of HPV that cause 70 percent of all cervical cancer cases worldwide, but they are expensive and offer only limited protection against other HPV types that cause cancer, according to the researchers. The new vaccine may help cover that gap in protection, they noted.

When the candidate vaccine was used with a substance such as alum to stimulate immune response, the animals were protected against infection by HPV type 16, the study found.

"Clinical studies are warranted" to assess the safety of these types of vaccines, wrote Richard Roden, of the Johns Hopkins University in Baltimore, and colleagues. If this new type of vaccine proves effective, "its simpler manufacturing process could make the local production of such a vaccine highly feasible, which might achieve the goal of producing it at sustainable prices in emerging countries and lead to its widespread implementation in the developing world," the researchers said.

The study appears online Tuesday in the Journal of the National Cancer Institute.

A broad-spectrum HPV vaccine could solve the shortcomings of current vaccines -- they're too expensive to be used in much of the world and they don't protect against enough HPV types -- Dr. F. Xavier Bosch, of the Catalan Institute of Oncology in Barcelona, Spain, wrote in an accompanying editorial.

The results of this study "open the door to a novel family of second generation HPV vaccines with significant potential value in the public health horizon. As soon as appropriate, Phase 1 trials in humans should be initiated," Bosch wrote.

More information

The U.S. Food and Drug Administration has more about HPV.



-- Robert Preidt



SOURCE: Journal of the National Cancer Institute, news release, May 26, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. A Broad-Spectrum Antibiotic with Activity Against MRSA and Pseudomonas Aeruginosa Would Earn a Higher Patient Share in the U.S. than in Europe for the Treatment of Hospital-Acquired Pneumonia
2. Life Spine(R) Announces Nationwide Market Introduction of KINETIC(R)-SL Dynamic Anterior Cervical Plating System
3. Women with previous abnormal cervical cells at higher risk for recurrence and invasive cancer
4. Dont Lower Age for Cervical Cancer Test, Study Urges
5. NuVasive Announces Acquisition of Cervical Total Disc Replacement Device
6. Womens Health Advocates To Moms: We Can Beat Cervical Cancer!
7. Human papillomavirus genotype distribution in New Mexico cervical cancers
8. Womens Integrative Health Encinitas OB/GYN Selects LUMA Cervical Imaging System
9. MRI and PET/CT improve cervical cancer patients chances for optimal treatment
10. Incidence rates of cervical cancer linked to deprivation
11. LUMA Cervical Imaging System Installed in Edina at Minnesota Gynecology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Broad-Spectrum Cervical Cancer Vaccine Shows Promise
(Date:6/27/2016)... ... June 27, 2016 , ... ... health professionals, announced today its affiliation with Tennessee Counseling Association. This ... the network of the Tennessee Counseling Association, adding exclusive benefits and promotional offers. ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, ... Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility ... home to some of the world’s leading providers of cereal and other breakfast foods. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... MEMS Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data ... analysis. Assessment of major trends with potential impact on the ... analysis of market segmentation which comprises of sub markets, regional ...
(Date:6/23/2016)... 23, 2016 Bracket , a leading clinical ... generation clinical outcomes platform, Bracket eCOA (SM) 6.0, at ... 26 – 30, 2016 in Philadelphia , ... Outcome Assessment product of its kind to fully integrate with ... Bracket eCOA 6.0 is a flexible platform for electronic clinical ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of ... Farma Brasil as the company,s second affiliate in Latin America . ... ... Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: