Navigation Links
Broad Institute earns grant to support pathbreaking diabetes study
Date:7/21/2008

Researchers at the Broad Institute of Harvard and MIT have received a grant to support novel, integrative research aimed at finding ways to encourage the human body to replenish the cells that are missing in type 1 diabetes. Awarded by the Juvenile Diabetes Research Foundation (JDRF), the $3M grant will fund work that knits together two interdisciplinary fields, genome biology and chemical biology, to address a fundamental question in human biology: can existing cells be coaxed to regenerate ones that are lost or damaged by disease?

"This grant will enable us to understand the inherent potential of human cells and how it might be harnessed in the future to improve health," said Stuart Schreiber, the grant's principal investigator and director of the Chemical Biology Program at the Broad Institute. "Our focus is on type 1 diabetes, a disease that typically surfaces in childhood and requires lifelong treatment, though our approach holds promise for practically any disease involving a cellular deficiency."

Diabetes stems from an inability to control the levels of glucose in the blood via a regulatory hormone called insulin. Type 1 diabetes is an autoimmune disease in which a person's pancreas stops producing insulin. The disease usually strikes in childhood, adolescence, or young adulthood, but lasts a lifetime. Patients with type 1 diabetes require lifelong insulin therapy, delivered through injections or a small, credit card-sized pump.

Yet that constant need for treatment might be lessened or perhaps eliminated altogether if the missing cells could be safely replaced. For example, surviving beta cells, while rare in type 1 patients, might be induced to multiply, creating enough copies of themselves to restore insulin supply. Or, perhaps other types of pancreatic cells could be redirected to become beta cells, a process known in scientific parlance as cellular reprogramming.

"From our initial proof-of-concept work, we know
'/>"/>

Contact: Nicole Davis
ndavis@broad.mit.edu
617-258-0952
Broad Institute of MIT and Harvard
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Broad-based group of physicians calls for improvement in stroke treatment
2. Euro RSCG Life Broadens X2 Expertise
3. Revolutionary HD Surgical Footage from North Shore-LIJ Surgeon to be Broadcast for the First Time on ABCs 20/20, National Geographic Channel
4. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
5. SATELLITE BROADCAST: Consumer Group Says Hillary Clintons Mandatory Health Insurance Plan is an Act of War on the Middle Class that Cant Afford $12k Policy
6. Verizon Introduces Broadband Video Call Center Link for Deaf or Hard-of-Hearing Customers in Mid-Atlantic Region
7. Incidental findings found when radiologists take a broader look at renal MRA
8. Sanarus Announces Partnership With Leading US Breast Care Physicians for the Next Generation Visica 2(TM) Treatment System for Fibroadenomas
9. Staffing Agency Hires Local Television News Team, Launches Broadband Network for Nurses
10. Abbott Broadens Use of i-STAT Handheld Blood Analyzer with CLIA Waiver Granted by FDA for CHEM8+ Test Cartridge
11. Regence CEO to Chair National Effort Promoting Broader Health Care Stewardship
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... LunaDress has recently announced its 2015 collection of ... on all of its special occasion dresses & wedding apparel. ... wedding gown. If you have no idea of what to ... different wedding dress styles and our dress experts are here ... current special offer, up to 80% off," the CEO of ...
(Date:12/20/2014)... The print component of Healthy Aging is ... approximately 160,000 copies and an estimated readership of 420,000. ... social media strategy and across a network of top ... version of the campaign, click here . , ... ladies of CTV’s The Social. Lainey Lui, Melissa ...
(Date:12/20/2014)... VogueQueen.com, a leading wedding dress wholesaler and retailer, has ... 2015. Great discounts are now offered on all of ... a discount, up to 80% off, when they place ... 2015. , VogueQueen.com has recently released its new arrival ... Many customers worldwide like VogueQueen’s special designs which feature ...
(Date:12/20/2014)... 2014 Angeldress.co.uk, the distinguished wedding dress ... worldwide dress fans. The company has recently updated its ... For the holiday season, Angeldress Blog has ... apparel. , Angeldress.co.uk prides itself in offering a huge ... service. All the company’s outfits are very carefully selected ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 Atore, Inc, ... company just launched first birthday focused portal on December ... BIRTHDAY MESSAGE” launched in both US and Japan. , ... MESSAGE : http://merrybirthday.net/message/ , MERRY BIRTHDAY MESSAGE ... birthday around the world. , Features, Choose from thousands ...
Breaking Medicine News(10 mins):Health News:2015 Collection of Wedding Dresses from LunaDress Online on Sale Now 2Health News:The ladies of The Social urge Canadian women to put themselves first over the holiday season and into the new year in Mediaplanet’s “Women’s Health” campaign 2Health News:VogueQueen Big Sale Online For The Coming 2015 2Health News:Trendy Professional Wedding Apparel Recommended by Angeldress Blog 2Health News:Atore, Inc. Releasing the First Birthday Portal 2
... carried out in terminally ill patients who are dying ... risk involved in these patients, // views Professor ... Professor Wilmut is appointed as the first director to ... ,Professor Wilmut feels that stem cell research though in ...
... Professor Michael Belkin and Dr Zohar Habot-Wilner working at the ... obesity causes ocular diseases.//br> ,They said that they have co-related ... field to come out with strong evidences that obesity is ... aware of the risks of being obese and due to ...
... and team have reported that the risk of heart ... siblings with heart disease.// Though earlier reports have shown ... and risk increases if parents have heart disease, but ... heart disease in adults if their siblings have heart ...
... has collected $2.3 million to be donated to a ... radio programs // . ,The money will be ... Brampton Hospital at Bovaird Drive and Bramalea Road, which ... event, Better Health Radiothon, was organized from Nov 15 ...
... Moores Cancer Center at the University of California, San ... Units (IU) of vitamin D3 // can reduce the ... cancer. ,"For example, breast cancer will strike ... detection using mammography reduces mortality rates by approximately 20 ...
... all the news channels of all the countries has infected 141 ... instilled fear // in US that it will soon spread quickly ... of the bird flu is very deadly and has infected people ... ,But so far its ability to spread from man to man ...
Cached Medicine News:Health News:Increased Risk Of Losing Sight In Obese People. 2Health News:Vitamin D Reduces Chances of Colon, Breast And Ovarian Cancers by 50% 2Health News:USA’s Plan to Tackle the Bird Flu Pandemi 2
(Date:12/19/2014)... 2014  RESMED INC. (NYSE: RMD ) today ... year 2015 results on Thursday, January 22, 2015, after the ... ResMed,s results will be issued after 1:00 p.m. US Pacific ... operating results and future outlook. The earnings call ... and the live webcast of the call can be accessed ...
(Date:12/19/2014)... 18, 2014   Aratana Therapeutics, Inc . ... focused on the licensing, development and commercialization of ... results from its pivotal field study of AT-001 ... in dogs with osteoarthritis.  In the study, dogs ... that were statistically significant compared to placebo (p<0.05) ...
(Date:12/17/2014)... and SAN DIEGO , Dec. 17, 2014 ... ; AEX: PHIA) and Volcano Corporation (NASDAQ: VOLC ... for cardiovascular applications, today announced that they have entered into ... commence a tender offer to acquire all of the issued ... or a total equity purchase price of USD 1 billion ...
Breaking Medicine Technology:ResMed To Announce Second Quarter 2015 Results 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8
... Spanish drug companies face a number of obstacles ...  From regulatory (FDA) and GMP compliance, to distribution agreements ... areas that must be coordinated.  Those issues have just ... U.S. company VPCI have entered into a joint association. ...
... Sherpa Clinical Packaging, a privately held provider of ... cutting ceremony today to mark the opening of ... San Diego, CA.  Sherpa,s employees and invited guests ... adjacent to the Althea Technologies campus in Sorrento ...
Cached Medicine Technology:Spanish Drug Companies Have New Support Option for the U.S. Market 2Sherpa Clinical Packaging Completes New Production Facility 2
... This compact system provides an ... preparation in the laboratory, satellite lab ... proven HEMA-TEK staining method with wedge-smear ... delivers complete standardization in a safe ...
It is a cardio-pulmonary exercise testing device....
... has digitally-controlled drive system which eliminates ... can wear out. There are no ... and fewer drive belts - resulting ... It can carry weights up to ...
... systems feature our internationally-acclaimed algorithm that ... algorithm has a proven record for ... situations; and it's just one of ... recognized market leader in the stress ...
Medicine Products: