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Brilliant blue G may shine in treating traumatic brain injuries
Date:2/11/2014

o hopefully avoid the additional damage that occurs when the swelling brain presses up against the hard, and usually protective, skull, following a traumatic brain injury. While the procedure has proven helpful, by the time increased intracranial pressure merits such a maneuver, more brain tissue already has sustained damage.

Vender and Dhandaphani want to intervene sooner. "What Kris is doing in the lab is blocking the process before it gets to the point where it hurts the brain tissue," Vender said. "That is what is exciting about it."

Their search for better therapies began by looking for differences in the cerebral spinal fluid of patients with and without a traumatic brain injury and finding higher levels of interleukin-1 was a major one. "We want to figure out if the interleukin we found in the cerebral spinal fluid is causing problems or are other problems causing interleukin to go up," Dhandapani said. They are betting it's the former.


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Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University
Source:Eurekalert  

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