Navigation Links
Brigham and Women's Hospital Researchers Demonstrate a More Direct Delivery of Cancer Drugs to Tumors
Date:4/20/2009

An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of their work appear on April 20, in an early online edition of the Proceedings of the National Academy of Science.

Boston, MA (Vocus) April 20, 2009 -- An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of their work appear on April 20, in an early online edition of the Proceedings of the National Academy of Science.

The team constructed the nanoparticles from a biodegradable, biocompatable, Food and Drug Administration-approved polymer which they chemically engineered to deliver a MAPK inhibitor. By inhibiting the MAPK signaling pathway, which is involved in a majority of human tumors, the nanoparticles hinder the multiplication of cancerous cells and predispose those cells to the cytotoxic effects of chemotherapeutic drugs. The team also modified the polymer to increase drug loading 20 fold, which overcomes a current drawback in nanomedicine, low efficiency of drug loading.

"Current chemotherapeutic drugs must be administered
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Lilly and Partners In Health, Brigham and Womens Hospital Team Up to Fight MDR-TB in Former Soviet Republics
2. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
3. Brigham and Womens Hospital Selects SinglePointe(TM) Automated Patient-Specific Medication Management Solution from Omnicell
4. Brigham and Associates and Insurance Recovery Group Launch Impairment Resources, a Joint Venture to Address Impairment Ratings
5. Combined Insurance Reports that Single Working Women's Week is a Good Time for Annual Review of Insurance Coverage
6. Kabul Under Virtual Lockdown for International Travelers, Progress Still Evident for Women's Programs
7. Easing Social Anxiety During the Holidays: Tips from Harvard Women's Health Watch
8. Jill Bolte Taylor Keynotes ATSU Women's Wellness Luncheon
9. Singapore Premier Women's Hospital Offers Contactless Surgery for Uterine Fibroids
10. Women's Health Services Announces New Associate
11. New research explores newborn in-hospital weight loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... (PRWEB) March 03, 2015 Introducing ... Dental Labs is a recognized leader in Digital ... produces the best dental replicas, leaving no ... 3D digital scanning, dental professionals are able to ... 3D printers consistently deliver remarkable quality while reducing ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 Birth ... announced today they now have over 130 certified instructors ... 1 in Germany. In addition, the company recently launched ... existing childbirth educator certification program . Birth Boot ... and her birth partner. The practical information can be ...
(Date:3/3/2015)... MA (PRWEB) March 03, 2015 The ... transformed the science of the little-known and incurable disease, ... its #CureFSHD campaign . The purpose of the ... FSHD, one of the most common forms of muscular ... off the campaign, today the FSH Society will begin ...
(Date:3/3/2015)... 03, 2015 Jack Coats, Chief Executive ... William A. Breukelman has been named to the company’s ... of the first fully integrated version of its Multiparametric ... analyzing the three-dimensional motion of the heart that is ... analysis at 15,300 points to the motion of a ...
(Date:3/3/2015)... Raritan Bay Medical Center is proud to ... photo contest held at the Woodbridge Center Mall in ... awareness for health and wellness in the Central New ... health and wellness tips. , Photos of visitors sharing ... and Facebook page where Facebook users voted on their ...
Breaking Medicine News(10 mins):Health News:Iverson Dental Labs Introduces 3D Digital Dental Technology for Superior Products 2Health News:Iverson Dental Labs Introduces 3D Digital Dental Technology for Superior Products 3Health News:Expectant Couples Worldwide Can Now Receive Training and Education in Natural Childbirth and Breastfeeding from Birth Boot Camp 2Health News:Share to be Aware: FSH Society Launches #CureFSHD Campaign 2Health News:Share to be Aware: FSH Society Launches #CureFSHD Campaign 3Health News:William A. (Bill) Breukelman Named to CardioWise, Inc. Board of Directors 2Health News:William A. (Bill) Breukelman Named to CardioWise, Inc. Board of Directors 3Health News:Raritan Bay Medical Center Announces Winners of “Picture of Health” Photo Contest 2
... , WASHINGTON , Jan. 15 ... with 22 national organizations, attended the first consortium meeting ... initiative to improve lupus diagnosis, treatment, and management among ... Rheumatology offices in Atlanta, Georgia from January ...
... FRANCISCO , Jan. 15 A Good Idea , a ... San Francisco , plans to give $100,000 to Haiti ... Community Giving contest sponsored by JPMorgan Chase & Co. , "While ... Bay Area, we feel that it is of the utmost importance to contribute ...
... , SANTA BARBARA, Calif. , Jan. 15 ... connecting essential micronutrients, especially vitamin A, with infants and children ... a disaster relief agency, Vitamin Angels has responded to ... Haiti , by shipping over 1 million children,s multivitamins. After ...
... , PHOENIX , Jan. 15 ... rice bran (SRB) nutrient research and technology, today announced a 17% ... to improve the company,s cost structure. The reduction, which is anticipated ... impact the workforce at Irgovel, NutraCea,s Brazilian subsidiary. , W. ...
... , OCEANSIDE, Calif. , Jan. 15 ... organizations that work with teens are tirelessly launching grassroots efforts to ... In many cities, the efforts are led by teens themselves. , ... cannot change the world.  But the people who see it can ...
... , Jan. 15 The March of Dimes has ... mothers and babies in Haiti imperiled by the devastating ... concerned about the thousands of pregnant women and moms caring for ... Dr. Jennifer L. Howse , president of the March of ...
Cached Medicine News:Health News:Lupus Foundation of America Collaborates with Federal Agencies and the U.S. Surgeon General's Office to Expand Medical Education on Lupus 2Health News:Lupus Foundation of America Collaborates with Federal Agencies and the U.S. Surgeon General's Office to Expand Medical Education on Lupus 3Health News:San Francisco Charity A GOOD IDEA to Give $100,000 to Haiti Victims Upon Winning Nationwide Charity Program 2Health News:Vitamin Angels Responds to Haiti Disaster 2Health News:NutraCea Announces Reduction in Workforce in U.S. Operations 2Health News:Movie Turns Into a Growing Movement to Reach Hurting Teens. 2Health News:Movie Turns Into a Growing Movement to Reach Hurting Teens. 3Health News:Movie Turns Into a Growing Movement to Reach Hurting Teens. 4Health News:Movie Turns Into a Growing Movement to Reach Hurting Teens. 5Health News:March of Dimes Supports Urgent Needs of Mothers and Babies in Haiti Earthquake 2
(Date:3/3/2015)... Mar. 03, 2015 Research and Markets ... "Global POC Diagnostics Market 2015-2019" report to ... the Global POC Diagnostics market to grow at a ... POC diagnostics are IVD devices and tools ... laboratory setting. The use of these devices helps in ...
(Date:3/3/2015)... VIEW, Calif. , March 3, 2015 ... (ML) Council today recognized world-class manufacturing companies ... 2015 Manufacturing Leadership Awards. ... a world of intensifying global competition and ... Awards have distinguished themselves by embracing breakthrough ...
(Date:3/3/2015)... 03, 2015 Research and Markets ... the "Telemedicine and Mobile Healthcare Solutions, Services, ... 2020" report to their offering. ... all terms that pertain to the use of ... remote clinical/non-clinical healthcare services. They form the ecosystem ...
Breaking Medicine Technology:Global POC Diagnostics Market 2015-2019 with Abbott Labs, Alere, Bayer Healthcare, Danaher, F. Hoffmann-La Roche & Johnson & Johnson Dominating 22015 Manufacturing Leadership Award Winners Announced 22015 Manufacturing Leadership Award Winners Announced 32015 Manufacturing Leadership Award Winners Announced 42015 Manufacturing Leadership Award Winners Announced 52015 Manufacturing Leadership Award Winners Announced 6Global Telemedicine and Mobile Healthcare Solutions, Services, and Devices: Market Analysis and Forecasts 2015 - 2020 2Global Telemedicine and Mobile Healthcare Solutions, Services, and Devices: Market Analysis and Forecasts 2015 - 2020 3
... Boston Scientific Corporation (NYSE: BSX ) today ... the 2010 Popular Science "Best of What,s New" ... Bronchial Thermoplasty System.  The awards recognize breakthrough products and technologies ... "For 23 years, Popular Science ...
... Topaz Pharmaceuticals Inc., a privately held specialty pharmaceutical company, ... and Chief Executive Officer (CEO).  Thomas Beck, M.D., who ... his role as Chief Medical Officer of the company. ... is concluding Phase 3 clinical trials to support a ...
Cached Medicine Technology:Alair® Bronchial Thermoplasty System Named 'Best of What's New' By Popular Science 2Alair® Bronchial Thermoplasty System Named 'Best of What's New' By Popular Science 3Alair® Bronchial Thermoplasty System Named 'Best of What's New' By Popular Science 4Topaz Pharmaceuticals Names Bob Radie Chief Executive Officer 2Topaz Pharmaceuticals Names Bob Radie Chief Executive Officer 3
Needle Knife, straight, full handle, non-reflective, 0.74 mm width....
Full Handle Laseredge Slit Blade Knife, 3.2 mm angled double bevel. Blade tip dimension: 14.4 mm x 3.2 mm x 4.0 mm....
Full Handle Laseredge Slit Blade Knife, 2.85 mm slit. Blade tip dimension: 14.1 mm x 2.85 mm x 3.3 mm....
Full Handle Laseredge Slit Blade Knife, 2.5 mm angled bevel up. Blade tip dimension: 14.4 mm x 2.5 mm x 3.7 mm....
Medicine Products: