Navigation Links
Brigham and Women's Hospital Researchers Demonstrate a More Direct Delivery of Cancer Drugs to Tumors
Date:4/20/2009

An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of their work appear on April 20, in an early online edition of the Proceedings of the National Academy of Science.

Boston, MA (Vocus) April 20, 2009 -- An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of their work appear on April 20, in an early online edition of the Proceedings of the National Academy of Science.

The team constructed the nanoparticles from a biodegradable, biocompatable, Food and Drug Administration-approved polymer which they chemically engineered to deliver a MAPK inhibitor. By inhibiting the MAPK signaling pathway, which is involved in a majority of human tumors, the nanoparticles hinder the multiplication of cancerous cells and predispose those cells to the cytotoxic effects of chemotherapeutic drugs. The team also modified the polymer to increase drug loading 20 fold, which overcomes a current drawback in nanomedicine, low efficiency of drug loading.

"Current chemotherapeutic drugs must be administered
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Lilly and Partners In Health, Brigham and Womens Hospital Team Up to Fight MDR-TB in Former Soviet Republics
2. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
3. Brigham and Womens Hospital Selects SinglePointe(TM) Automated Patient-Specific Medication Management Solution from Omnicell
4. Brigham and Associates and Insurance Recovery Group Launch Impairment Resources, a Joint Venture to Address Impairment Ratings
5. Combined Insurance Reports that Single Working Women's Week is a Good Time for Annual Review of Insurance Coverage
6. Kabul Under Virtual Lockdown for International Travelers, Progress Still Evident for Women's Programs
7. Easing Social Anxiety During the Holidays: Tips from Harvard Women's Health Watch
8. Jill Bolte Taylor Keynotes ATSU Women's Wellness Luncheon
9. Singapore Premier Women's Hospital Offers Contactless Surgery for Uterine Fibroids
10. Women's Health Services Announces New Associate
11. New research explores newborn in-hospital weight loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... (PRWEB) July 22, 2014 DocbookMD ... process of deploying one of the largest physician-centric mobile ... ( MHMD ) in Houston. , Created by Austin-based ... the DocbookMD application will be embedded into MHMD’s Accountable ... searched for the best technology to put this capability ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Air Conditioning ... are now an authorized Daikin comfort pro dealer. This ... Daikin indoor heating and cooling system equipment. Only a ... is thoroughly reviewed before being approved. , Daikin co-developed ... in the Split System Air Conditioning Market. They are ...
(Date:7/22/2014)... United Benefit Advisors (UBA), the nation's leading independent ... insurance veteran with more than 15 years of experience, ... in the company's Chicago office. , UBA Board Chairman ... to accept this important, strategic position with UBA. ... facing UBA and its Partners as we move forward ...
(Date:7/22/2014)... Reinberg HealthDay Reporter TUESDAY, ... during pregnancy may be more likely to have children with ... found that, compared with children born from mothers of normal ... had up to 20 to 30 percent higher odds of ... of pediatrics at Children,s Hospital of Pittsburgh. Forno,s team ...
(Date:7/22/2014)... Plate Club you eat pretty much everything you put ... Cornell University study shows that the average adult eats 92% ... plate. "If you put it on your plate, ... of the forthcoming book, Slim by Design, Professor of Marketing ... Wansink and co-author Katherine Abowd Johnson analyzed 1179 diners and ...
Breaking Medicine News(10 mins):Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 4Health News:Air Conditioning & Heating Inc. Now an Authorized Daikin Comfort Pro Dealer 2Health News:Industry Leader Les McPhearson Joins United Benefit Advisors as New Chief Executive Officer 2Health News:Industry Leader Les McPhearson Joins United Benefit Advisors as New Chief Executive Officer 3Health News:Industry Leader Les McPhearson Joins United Benefit Advisors as New Chief Executive Officer 4Health News:Industry Leader Les McPhearson Joins United Benefit Advisors as New Chief Executive Officer 5Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 2Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 3
... Tips for Days During and ... Following ... there,s smoke,and that,s not good for your respiratory health, cautions experts ... 1902. Residents far beyond the burn areas should monitor their ...
... (October 24, 2007) -- Combat physicians in war-torn areas ... predict which casualties require massive blood transfusions (MT), and ... research published in the October issue of The Journal ... that the presence of a combination of three variables ...
... Waichman Alonso LLP Announces Opening of Dedicated Claims Center To, ... Leads ... The defective Medtronic Sprint,Fidelis Defibrillator Leads were implanted into ... for serious injury if a Sprint Fidelis,Lead fractures. As a ...
... Agree to Fair Union Election Process, ORANGE, Calif., ... Jr., will be among those joining hospital,workers from Mission ... a procession Saturday outside the headquarters of the St. ... a union at SJHS hospitals have,asked the health system,s ...
... , WEDNESDAY, Oct. 24 (HealthDay News) -- British scientists say ... , They said the discovery will prove valuable to scientists ... of the study, published in the Oct. 25 issue of ... a new line of research that eventually enables researchers to ...
... of Smart Choices will provide practical advice in approaching ... a home at the annual meeting of the Institute ... Seattle. , Dr. Ralph L. Keeney, Research Professor of ... University, is co-author of Smart Choices, A Practical Guide ...
Cached Medicine News:Health News:Fire Season: Respiratory Health a Concern 2Health News:Fire Season: Respiratory Health a Concern 3Health News:Early predictive model may be new 'weapon' against leading cause of death on battlefield 2Health News:Medtronic Sprint Fidelis Defibrillator Lead Lawsuit Claims Center Opens to Aid Victims 2Health News:Medtronic Sprint Fidelis Defibrillator Lead Lawsuit Claims Center Opens to Aid Victims 3Health News:Trouble deciding? 2Health News:Trouble deciding? 3
(Date:7/22/2014)... 22, 2014 Sanofi Pasteur, the vaccines division of ... today that the first lots of Fluzone ® (Influenza ... released by the U.S. Food and Drug Administration (FDA) for ... the first of at least 65 million doses of seasonal ... to U.S. health care providers and pharmacies in August. ...
(Date:7/22/2014)... 2014 The Intellectual Property ... the world,s leading provider of intelligent information ... Cortellis Clinical Trials Intelligence , its global ... with the documentation of more than 180,000 ... greater and quicker access to critical data ...
(Date:7/22/2014)... , July 22, 2014 The ... physicians is spreading to previously rep-friendly specialties, according ... sales and marketing consulting firm ZS Associates.      ... than 200 U.S. pharmaceutical sales teams. The report ... prescribers meet with the pharmaceutical sales reps who ...
Breaking Medicine Technology:Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 2Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 3Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 4Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 5Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 6Sanofi Pasteur Begins Shipping Seasonal Influenza Vaccine for Upcoming 2014-2015 Season in United States 7Thomson Reuters Cortellis Clinical Trials Intelligence Reaches Industry Milestone with 180,000 Clinical Trials 2Thomson Reuters Cortellis Clinical Trials Intelligence Reaches Industry Milestone with 180,000 Clinical Trials 3Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 2Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 3Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 4Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 5
... Pharmaceuticals, Inc. (Nasdaq: ISIS ), the leader in ... overview at the 17th Annual NewsMakers in the Biotech Industry ... at the Millennium Broadway Hotel & Conference Center in New ... will be available on the "Investors & Media" section of ...
... -- Synutra International, Inc. (Nasdaq: SYUT ), ... producer, marketer and seller of nutritional products for infants, ... present at Citi,s Greater China Investor Conference to be ...  Management is currently scheduled to meet with institutional investors ...
Cached Medicine Technology:
... matrix constructed of cross-linked collagen fibers ... through a proprietary 360 accretion process. ... aspirate, Healos provides an excellent environment ... differentiation. The hydroxyapatite-coated collagen microfibers in ...
Sharp Weitlaner Retractor....
Weitlaner retractor, blunt....
Bruns (Volkmann) bone curette, with Novotex plastic handle (autoclavable in autoclave up to 143C by 3 bar), 9, oval....
Medicine Products: