Navigation Links
Brief exam diagnoses cognitive impairment in ALS patients
Date:6/22/2011

Patients with amyotrophic lateral sclerosis (ALS) could lose brain function earlier than is noticeably detectable, affecting their ability to make decisions about their care. Physicians need a method to assess these sensitive changes in brain function, without the need for extensive neuropsychological tests.

Penn State College of Medicine researchers created a brief exam that identifies frontotemporal disease (FTD) deficits in judgment and problem-solving in ALS patients. FTD is a decline in function and behaviors associated with the frontal and temporal lobes of the brain. As the disease progresses, it effects higher-level language processing, attention span, and reasoning, with indirect effect to memory. The disease is often found in ALS patients.

"Cognitive changes in ALS patients can have a major impact on management of the disease, due in part to the various patterns of behavioral changes that arise," said Claire Flaherty-Craig, Ph.D., assistant professor, Department of Neurology. "Dysfunction could provide a significant obstacle when it comes time to make important end-of-life decisions, such as placement of feeding tubes, use of a ventilator, and clarification of advance directives. It has been shown that patients with ALS and FTD have a poorer prognosis than those with ALS alone."

The Penn State Brief Exam of Frontal and Temporal Dysfunction Syndromes (PSFTS) was developed for the multi-disciplinary ALS clinic at Penn State Milton S. Hershey Medical Center to identify patients with frontal dysfunction and was refined to differentiate three subtypes of FTD. The exam has been used in more than 200 patients and is now standard of care at the Medical Center.

Researchers published their findings on the PSFTS in the journal Cognitive and Behavioral Neurology.

Thirty-eight patients completed both the brief exam and a comprehensive neuropsychological exam. From this, thirteen ALS patients not showing any deficiencies on the bri
'/>"/>

Contact: Matthew Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State
Source:Eurekalert

Page: 1 2

Related medicine news :

1. News brief: Benefit of HPV Vaccination, Frequent Screening for Women over 41 is Likely to be Low
2. News brief: ALDH associated with worse overall survival in patients with pancreatic adenocarcinoma
3. NIH-FDA Joint Briefing on Regulatory Science Collaboration
4. Congressional Staff Briefing, Wed., Feb. 24 on Mental Health, Medicaid & Block Grants
5. Increased Government Scrutiny of Companies That Use Independent Contractors, Consultants, or Freelancers: Are You Ready? Learn More at Complimentary Breakfast Briefing
6. FASEB President Addresses Congressional Audience at Coalition for Health Funding Briefing on Public Health
7. News briefs from the March issue of Chest
8. CCH Issues Briefing on Tax Provisions of Health Care Reform Legislation
9. CCH Briefing Highlights Employer, Medicare Provisions of Health Care Reform Proposals
10. News briefs from the April issue of Chest
11. ClubCorp Hosts Author Dave Guerra in a Nationwide Executive Briefing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... Dallas, Texas (PRWEB) April 22, 2015 ... Pipeline Review, H1 2015” provides comparative analysis ... The report strengthens R&D pipelines by identifying ... and best-in-class products. Complete report with TOC ... , The report also reviews key players ...
(Date:4/21/2015)... TX (PRWEB) April 21, 2015 The ... announced today it is opening its first freestanding emergency ... in Chandler, Arizona and will be licensed under Dignity ... the Dignity Health and Adeptus Health joint venture. , ... Regional and Mercy Gilbert Medical Centers said the new ...
(Date:4/21/2015)... & New York, NY (PRWEB) April 21, 2015 ... global provider of advanced delivery technologies and development ... today announced the launch of ADVASEPT™ Lock, a ... and efficient delivery of injectable medications. Easily opened, ... a safe, convenient and functional container closure with ...
(Date:4/21/2015)... Carinsurancehints.com has released a new blog post presenting ... auto insurance prices . , Commuting on ... should review their insurance options before deciding what plan ... forms. Some of the popular policies provide liability, collision ... rates and find the best prices in their area ...
(Date:4/21/2015)... April 21, 2015 This year, in ... Skin Types, Inc.® (FIRST) will publish a unique awareness ... will run throughout the month of May and carry ... to Someone." The positioning was chosen to encourage ... skin disorder and to help support our mission of ...
Breaking Medicine News(10 mins):Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 2Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 3Health News:Catalent Announces the Expansion of its Advanced, Aseptic, Glass-Free Injectable Platform with New ADVASEPT™ Lock Delivery Technology 2Health News:Heavily Circulated Roads Can increase Auto Insurance Costs 2Health News:May is Ichthyosis Awareness Month. Use Your Voice. 2
... /Xinhua-PRNewswire/ -- WuXi PharmaTech,(Cayman) Inc. (NYSE: ... device research and development outsourcing company with ... announced it has reached an agreement,with Johnson ... of,Janssen Pharmaceutica, N.V. (J&JPRD) to expand its ...
... ST. LOUIS, Oct. 15 Young Innovations, Inc.,(Nasdaq: ... third quarter,earnings results with a live and on-demand web ... Central Time. A live audio broadcast of the,call will ... the live audio broadcast will also be available through ...
... Options,(CCO), a leader in the development of innovative online, ... agreement with,the American Association for the Study of Liver ... unique Conference Coverage of AASLD,s,Liver Meeting(R) 2008, which will ... 4, 2008., "Clinical Care Options has a proven ...
... DUBLIN, Ohio, Oct. 15 Foresight Corporation ... Debra Strickland has joined the,company,s Development division ... http://www.newscom.com/cgi-bin/prnh/20081015/CLW134 ), In this role, ... customers to,propose and design new technical solutions, ...
... 15 Darwin,Professional Underwriters, Inc. (the "Company") (NYSE: ... meeting of the Company,s stockholders held on October ... Plan of Merger,(the "Merger Agreement"), dated as of ... Company Holdings, Ltd ("Allied World") and Allied,World Merger ...
... a sentry guarding the castle walls, a molecular messenger inside ... that could allow the invasion of an insidious enemy: Cancer. ... in its tracks, preventing an error that could lead to ... suggests that to be able to prevent abnormal cell proliferation, ...
Cached Medicine News:Health News:WuXi PharmaTech Expands Collaboration for Fully Integrated Services 2Health News:Young Innovations, Inc. Provides Third Quarter Conference Call Details 2Health News:American Association for the Study of Liver Diseases Enters Into Agreement With Clinical Care Options as Its Authorized Online Conference Coverage Provider for the Liver Meeting(R) 2008 2Health News:Debra Strickland joins Foresight Corporation in time for HIPAA 5010 Mandate 2Health News:Darwin Stockholders Adopt Merger Agreement with Allied World 2Health News:Darwin Stockholders Adopt Merger Agreement with Allied World 3Health News:Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find 2
(Date:4/21/2015)...  CryoLife, Inc. (NYSE: CRY ), a leading ... and vascular surgery, announced today that 2015 first quarter ... 2015.  On that day, the Company will hold a ... Time to discuss the results, followed by a question ... Chairman, President and Chief Executive Officer of CryoLife, Inc. ...
(Date:4/21/2015)... Mary Kelly, Ph.D ., is helping members of the Medical Group Managers Associations (MGMA) deal ... http://photos.prnewswire.com/prnh/20150420/199849 ... ... ... pulling your hair out of your head or going bankrupt," said Kelly, a popular keynote ...
(Date:4/21/2015)...  Edico Genome today announced a collaboration with ... processors to accelerate next generation sequencing (NGS) data ... primary and secondary NGS analysis in real time, ... analysis in the cloud and holds benefits for ... such as analysis of population-scale genomic data. ...
Breaking Medicine Technology:CryoLife Announces Release Date and Teleconference Call Details for 2015 First Quarter Financial Results 2Medical Group Managers Build Effective Practices with Strategies from Leadership Expert Mary Kelly 2Medical Group Managers Build Effective Practices with Strategies from Leadership Expert Mary Kelly 3Medical Group Managers Build Effective Practices with Strategies from Leadership Expert Mary Kelly 4Medical Group Managers Build Effective Practices with Strategies from Leadership Expert Mary Kelly 5Edico Genome Collaborates with Intel to Overcome Big Data Bottleneck in Next-Generation Sequencing 2Edico Genome Collaborates with Intel to Overcome Big Data Bottleneck in Next-Generation Sequencing 3
... Inc.,("CeloNova"), leading and accelerating healthcare solutions through ... breakthrough,results from the ATLANTA study of the ... the 20th Annual International Symposium on,Endovascular Therapy ... Corrado Tamburino, MD, President of the ...
... Ortho Women,s Health,& Urology(TM), Division of ... for ORTHO EVRA(R),(norelgestromin/ethinyl estradiol transdermal system) to ... includes two new additional estimates of relative,risk ... of 1.1,(indicating no increase in risk) and ...
Cached Medicine Technology:CeloNova BioSciences Introduces a New Class of Coronary Stent: The CATANIA(TM) Coronary Stent System with NanoThin Polyzene(R)-F 2ORTHO EVRA(R) Prescribing Information Updated 2ORTHO EVRA(R) Prescribing Information Updated 3
... Microplate washer MP-1200 is a compact ... system. Its internal micropumps enable the ... discharge from all types of microtiter ... be washed in rows of 8 ...
Wellwash 384 is an efficient, rapid and reliable washing process for high-throughput screening. It has been designed to optimize the washing process and ensure the best results. Available in 384 or 9...
... Designed and manufactured specifically ... MultiWash II delivers the ... demand. The MultiWash II ... dependable accuracy, while providing ...
... PDQ Plus for the determination of A1c is ... The PDQ Plus is a fully automated analyzer ... for the ultimate in safety and positive identification. ... well known to be interference-free and to produce ...
Medicine Products: