Navigation Links
Brewing up a gentler java: Dark-roasted coffee contains stomach-friendly ingredient

SAN FRANCISCO, March 21, 2010 With stomach irritation preventing almost 2 out of every 10 people from enjoying coffee, scientists today reported discovery of several substances that may be among the culprits responsible for brewing up heartburn and stomach pain in every cup.

Their report, presented here at the 239th National Meeting of the American Chemical Society, included the counter-intuitive finding that espresso, French roast, and other dark-roasted coffee may be easier on the tummy because these roasts contain a substance that tells the stomach to reduce production of acid.

The research could lead to a new generation of stomach-friendly brews with the rich taste and aroma of regular coffee, the scientists said.

"This discovery is going to help a lot of people who suffer from coffee sensitivity," say Veronika Somoza, Ph.D. from the University of Vienna in Austria, and Thomas Hofmann, Ph.D. from the Technische Universitt Mnchen in Germany, who conducted the study. "As coffee-lovers, we're very excited about this research."

Estimates suggest that up to 40 million people in the United States alone either avoid coffee, or cannot drink as much as they like, due to stomach irritation. Doctors think that chemicals in coffee cause the stomach to overproduce acid. Some coffee drinkers take antacids or drink decaffeinated coffee in an effort to reduce this effect. Others turn to a small but growing number of specialty coffee brews marketed as stomach friendly.

"The problem is that studies have not verified the stomach irritating potential of coffee or its components, until now," Somoza said. "Manufacturers currently make 'stomach friendly' coffees by processing raw coffee beans with steam or solvents intended to reduce levels of the irritants. But their effectiveness is unclear."

The processes used to produce stomach-friendly coffee also can reduce the amount of healthful substances in the coffee, including some that scientists have linked to benefits such as protection against diabetes and heart disease, Somoza said. In addition, the processing can affect the robust taste and smell of coffee.

To study the irritants in coffee, the scientists exposed cultures of human stomach cells to a variety of different coffee preparations, including regular, dark-roast, mild, decaffeinated, and stomach-friendly. They identified several substances that appeared to trigger chemical changes associated with increased acid production. These substances include caffeine, catechols, and other ingredients.

"Our data show, for the first time, that caffeine, catechols and N-alkanoly-5-hydroxytryptamides are those coffee components that stimulate molecular mechanisms of stomach acid secretion in human stomach cells," Somoza said. Most of them are indeed removed by steam or solvent treatment of the raw coffee bean. We found out there's no single, key irritant. It is a mixture of compounds that seem to cause the irritant effect of coffee."

The scientists unexpectedly found that one of the coffee components, N-methylpyridium (NMP), seems to block the ability of the stomach cells to produce hydrochloric acid and could provide a way to reduce or avoid stomach irritation. Since NMP is generated only upon roasting and not found in raw coffee beans, darker-roasted coffees contain higher amounts of this stomach-friendly coffee ingredient. Dark- roasted coffee can potentially contain up to twice as much of the ingredient as light-roasted coffees, but its levels can vary widely depending on the variety of coffee bean and the roasting method, Somoza noted.

"Since NMP is generated upon roasting, dark-roast coffees contain high amounts of this stomach friendly coffee ingredient," Hofmann and Somoza said. "Now, there is hope for a good morning start with a freshly brewed cup of optimized stomach friendly coffee."

The scientists are testing different varieties of raw coffee beans and different roasting methods in an effort to boost NMP levels to make a better stomach-friendly coffee. They hope to test the new brew in human volunteers later in 2010.


Contact: Michael Bernstein
American Chemical Society

Related medicine news :

1. Coffee Drinking and Caffeine Associated With Reduced Risk of Hospitalization for Heart Rhythm Disturbances
2. Coffee Is Generally Heart-Friendly
3. Coffee, Tea Might Stave Off Diabetes
4. Coffee, Exercise Fight Prostate Cancer
5. New Simply...Go-Gurt Contains No High Fructose Corn Syrup, Artificial Flavors or Colors
6. Best Selling, Non Toxic Skin Brightener Does the Job Using Safe, Healthy Ingredients and Introduces New Anti Aging Ingredients
7. Salmonella Tennessee Identified in a Processed Food Ingredient
8. Latest quality and purity specifications for food ingredients help protect consumers
9. Everyone Could Benefit From Dr. Clint Pearman's New Book, "The Gift: Twelve Ingredients To Improve Your Life."
10. Ingredient in Botanicals Tied to Urinary Cancer
11. Beer Ingredient Eyed in Prostate Cancer Prevention
Post Your Comments:
Related Image:
Brewing up a gentler java: Dark-roasted coffee contains stomach-friendly ingredient
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Final Cut Pro X users can now reveal the media of their split ...
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... On June ... sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, ... of the city’s history as home to some of the world’s leading providers of ...
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs ... College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. ... treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ... company developing innovative inhaled drugs, announced today that it ... Russell Investments reconstituted its comprehensive set of U.S. ... "This is an important milestone for Pulmatrix," said ... increase shareholder awareness of our progress in developing drugs ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
Breaking Medicine Technology: