Navigation Links
Breastfeeding protects children against peptic ulcer bacterium
Date:3/8/2010

Young children in developing countries are infected at an early age with the bacterium Helicobacter pylori, which can cause peptic ulcers and stomach cancer. New findings show that childrens immune responses help in fighting the bacteria. In addition, breastfeeding and better hygiene appear to protect against infection. The results provide hope for a vaccine, according to research from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

The study has been performed in cooperation between the Sahlgrenska Academy in Gothenburg and the International Centre for Diarrhoeal Disease Research in Bangladesh, an international research institute for gastrointestinal infections. This is the first time that researchers have made a detailed study of when children are infected with peptic ulcer bacteria and develop immune responses to the infection. The study followed 250 children in Bangladesh from birth to the age of two years.

The results from the study suggest that breastfeeding can protect children against early infection with the peptic ulcer bacterium. Breastmilk contains antibodies, that is molecules that can bind onto foreign substances, for example bacteria, and help prevent infection.

"Children who have received high levels of antibodies to the peptic ulcer bacteria from their mothers during breastfeeding were infected later than the children who had not received such high levels of antibodies," says Taufiqur Bhuiyan, PhD (medicine) at the Department of Microbiology and Immunology at Sahlgrenska Academy.

However, at the age of two years half the children in the study were infected with peptic ulcer bacteria. Around ten per cent of the children nevertheless managed to get rid of the infection. This was probably due to the children themselves producing antibodies to the infection.

"To date we do not, however, know whether the childrens antibodies manage to fight the bacteria on their own or whether the antibodies are a sign of a more general activation of the immune system. We have shown that the children can also activate their T cells, which release signals to bring other parts of the immune system into play," says Bhuiyan.

It also emerged that more children are infected in the spring and autumn than at other times of the year.

"This finding is very interesting, because the pattern of infection is similar to that of other infectious diseases, such as cholera. This supports the notion that important sources of infection for peptic ulcer bacteria are vomiting and diarrhoea from people affected by acute gastrointestinal infections," says Bhuiyan, who notes that a simple measure to prevent the spread of infection is improved hygiene.

Another possible measure to prevent infection is to try to develop a vaccine that can be given to young children. The new knowledge on how childrens antibodies and immune systems function during the early course of infection may help in designing new vaccines against the peptic ulcer bacterium. The task of the vaccine is to prevent the infection and consequently secondary diseases, which may be peptic ulcer and, in the worst case, stomach cancer, one of the most common forms of cancer around the world.


'/>"/>

Contact: Anna Lundgren Ph.D.
anna.lundgren@microbio.gu.se
46-070-226-4574
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Eating junk food whilst pregnant and breastfeeding may lead to obese offspring
2. Public Health and Need for Consistent Standards Preclude Exception for Breastfeeding Mother in National Medical Licensing Test
3. Breastfeeding does not protect against asthma, allergies
4. Breastfeeding does not protect children against developing asthma or allergies
5. Massachusetts State Court Hears Suit by Breastfeeding Mother on Medical Licensing Exam
6. Mass. Judge Denies Request by Breastfeeding Mother for More Break Time on Medical Licensing Exam
7. Purified Fish Oil Concentrates Offer Solution to Current Seafood Controversy for Pregnant and Breastfeeding Women!
8. Breastfeeding Does Not Create Sagging Breasts; Study Throws Out Old Wives Tale
9. Breastfeeding study dispels sagging myth
10. APHA Adopts New Policies on Food Safety, Global Climate Change, Multidrug-Resistant Organisms, Breastfeeding and Feminine Hygiene
11. More girls than boys benefit from breastfeeding, Hopkins Childrens research shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... ... San Francisco dentist, Dr. Ben Amini , the founder at CitiDent, ... capable of taking digital impressions of teeth and gums. Conventional bite impressions have lagged ... , in terms of speed, efficiency and patient comfort. Increasingly, digital impressions are being ...
(Date:1/16/2017)... ... ... NexTec Group has been selected as a member of the Bob Scott’s ... the field of midmarket financial software. , Members of the VAR Stars were selected ... based on revenue and those firms chosen represent a wide range of size and ...
(Date:1/15/2017)... , ... January 15, 2017 , ... ... Community Outreach is a program that strives to better communities around the world ... locations’ community. It also provides the opportunity for team members to become involved ...
(Date:1/15/2017)... ... January 15, 2017 , ... Accreditation ... achieved accreditation for its specialty care services. Albertsons Companies is the largest ... care service for pharmacy patients. , Accreditation by ACHC reflects Albertsons Companies’ dedication ...
(Date:1/15/2017)... ... January 15, 2017 , ... San Francisco ... eight Bay Area counties for 2017. Almost 1,000 nominations were submitted and a ... award process. Results were announced the magazine’s January 2017 issue . , ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... PORTLAND, Oregon and PUNE, India ... According to a new report published by Allied Market ... Global Opportunity Analysis and Industry Forecast, 2014-2022," the ... million by 2022, from $5,768 million in 2015, growing ... The chemical & gas sterilization segment dominated the market ...
(Date:1/16/2017)... Bill is an internationally experienced medical device industry executive ... with global medical device companies, including Smith & Nephew, Angiodynamics, Orthovita ... products and building successful businesses in the sector and has worked ... and North America . ... Educated at the University of Edinburgh (Dental ...
(Date:1/16/2017)... 2017 CBDRx, the world,s premiere nutraceutical hemp ... rich hemp extract to Veteran,s groups across the country. ... hemp extract to Veteran,s groups across the United States.  ... in the world and through their passion, CBDRx honors ... phyto-nutrient rich hemp extract available. ...
Breaking Medicine Technology: