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Breastfeeding, other factors may affect risk of breast cancer type
Date:8/25/2008

cancer.

The investigators found that reproductive risk factors varied considerably by breast cancer subtype. For example, early age at menarche was associated with risk of HER2-overexpressing disease but not with any other subtype. Breastfeeding for 6 months or longer was associated with a lower risk of luminal cancer as well as triple-negative cancer, a type that can be particularly aggressive and difficult to treat. Both late age at menopause and use of estrogen plus progestin hormone therapy were associated with an increased risk of luminal disease. Finally, no differences in risks associated with number of children or the age when a woman first gave birth were observed by subtype.

The study authors concluded that their results indicate that "certain reproductive factors may have a greater impact on risk of certain molecular subtypes of disease compared to others." They added that additional studies on the causes of breast cancer subtypes are needed to better understand the biology of the disease.


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Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Page: 1 2

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