Navigation Links
Breast milk may provide a personalized screen of breast cancer risk
Date:4/4/2011

ORLANDO, Fla. Breast cancer risk can be assessed by examining the epithelial cells found in breast milk, according to preliminary study results presented at the AACR 102nd Annual Meeting 2011, held April 2-6.

This screening method has the potential to provide a personalized assessment of breast cancer risk, said lead researcher Kathleen F. Arcaro, Ph.D., associate professor of veterinary and animal sciences at the University of Massachusetts Amherst. Given that roughly 80 percent of women give birth, this screen would also cover a large percentage of the female population.

Arcaro and colleagues collected breast milk samples from about 250 women who were scheduled for or who had a breast biopsy. The women submitted fresh samples, which were processed within 24 hours of expression; they provided samples from both breasts.

The researchers recruited about 90 percent of their study population from the Love/Avon Army of Women, which registers women who are willing to participate in breast cancer research. The American Association for Cancer Research is the scientific partner in this effort.

Once researchers received the samples, they isolated the epithelial cells (the potentially cancerous cells) in the breast milk. Then they isolated the DNA to look for epigenetic signals (attachment of methyl groups to DNA), which are the signals that tell the body those genes that should be expressed. These signals were then compared with breast cancer risk assessed using the biopsy results.

Arcaro and colleagues analyzed three genes: RASSF1, GSTP1 and SFRP1. "More than 35 genes have been shown to be methylated in breast cancer," she said.

Of the 104 women with a non-proliferative (low-risk) lesion, results showed no difference in the average epithelial DNA methylation of their biopsied breast vs. non-biopsied breast for RASSF1 and GSTP1. For SFRP1, however, the average methylation was higher in the biopsied breast. Imp
'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
2. Low forms of cyclin E reduce breast cancer drugs effectiveness
3. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
4. For Some Breast Cancer Patients, Shorter Radiation Works Well
5. Short-term radiation therapy successful on breast cancer
6. Few Women at High Risk for Breast Cancer Take Tamoxifen
7. Hormone May Prevent Aggressive Breast Cancer
8. MSU researcher linking breast cancer patients with alternative therapies
9. MRI May Not Add Value to Routine Breast Cancer Care
10. Breast Cancer Stats Differ Racially Despite Similar Mammogram Rates
11. Businesses Rally Big Efforts to Benefit the Susan G. Komen Phoenix Affiliates Fight Against Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now treating patients with back ... hip pain, neck pain, stiffness, muscle spasms, and numbness. , Dr. Toumayan received ... went on to earn his title of Doctor of Chiropractic from the Palmer College ...
(Date:8/28/2015)... ... August 28, 2015 , ... Northridge dentists Dr. Elyson ... For just $199, patients can currently receive a one hour treatment of this teeth ... but it includes a number of unique features that can turn teeth up to ...
(Date:8/28/2015)... La Mirada, Ca (PRWEB) , ... August 28, ... ... are now administering medical evaluations for those seeking to go deep sea diving. ... pressure, possible oxygen toxicity, and decompression sickness; for these reasons, it is vital ...
(Date:8/28/2015)... Washington, DC (PRWEB) , ... ... ... Atlantic Information Services, Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive ... newest CMS-backed alignment demonstration approved for a December 2015 launch; and Idaho’s ...
(Date:8/28/2015)... ... ... External Counterpulsation, also known as ECP or EECP, is a proven treatment ... ECP) machines with a full clinic licence to help people prevent and reverse heart ... prevent and reverse heart disease through its evidence-based integrative approach to heart ...
Breaking Medicine News(10 mins):Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Healthpointe Now Offering Scuba Physicals 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:Buy New External Counterpulsation (EECP or ECP) With Heart Fit Clinic 2
... research center focused,on improving the quality of life of ... Chattanooga, led by a world-renowned researcher whose,concepts and tools ... The Siskin Center for Child and Family Research ... nonprofit organization focused,on education, outreach and support for children ...
... DIEGO, Dec. 3 Cardium Therapeutics,(Amex: ... presenting a webcast providing,an investor presentation, corporate update ... The webcast will be presented following the ... and can be accessed at, http://www.investorcalendar.com/IC/CEPage.asp?ID=138418 at ...
... place objects in the wound, researchers say , , ... disorder where people wound themselves and then place ... among American teens, especially girls, researchers say. , ... Radiological Society of North America,s annual meeting in ...
... 3 NewCardio, Inc.,(OTC Bulletin Board: NWCI) a cardiac ... a restructure of the going-forward terms of,its December 27, ... investors,in the transaction have exercised a portion of their ... sheet. This will extend the,Company,s cash reserves to ...
... of New York State,s Metro Services has chosen BRANDEMiX, the NYC-based ... brand and launch an employee communications campaign in support of their ... ... December 3, 2008 -- The Cerebral Palsy Associations of New York ...
... their family and friends put their feet where their mouths were on ... charity in the inaugural HBA Great Australian Run. , ... Melbourne, VIC ... employees and their family and friends put their feet where their mouths ...
Cached Medicine News:Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 2Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 3Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 4Health News:Cardium Announces Investor Presentation and Corporate Update Webcast 2Health News:'Self-Embedding' a Troubling Trend Among Teens 2Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 2Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 3Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 4Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 5Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 6Health News:BRANDEMiX Selected to Launch Cerebral Palsy Associations of NYS Metro Services New Strategic Plan 2Health News:HBA People Walk the Talk for Better Health in the HBA Great Australian Run 2
(Date:8/28/2015)... , Aug. 28, 2015 ... has announced the addition of the "Investigation ... to their offering. Developed by Pharmacia ... prostaglandin receptor agonist which effectively reduces intraocular pressure. ... FDA, latanoprost (under the trade name of Xalatan) ...
(Date:8/28/2015)... -- Perrigo Company plc ("Perrigo") (NYSE: PRGO ; ... MYL ) shareholder vote regarding its planned unsolicited ... Mylan,s offer to Perrigo shareholders have always been, and ... reflection of the value available to Perrigo shareholders, and ... has allowed its shareholders to consider," said Joseph ...
(Date:8/28/2015)... 28, 2015 , Joint research by ... from Biostar , Published in ,Stem Cells Translational ... lifespan through multiple IV administration of Adipose-derived MSC ... expectancy found , Commercialization within 5 years expected ... possibility that adult mesenchymal stem cells (MSCs) may extend ...
Breaking Medicine Technology:China Latanoprost Market Investigation Report 2015-2019 2Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 2Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 3Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 4Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 5Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2
... The Astellas European Foundation is delighted to announce the winner ... of the University of Geneva, Switzerland Last evening, ... of US$ 300,000 to support work on their project entitled ... liver transplantation for hepatocellular carcinoma , at the Astellas European ...
... 2011 Unilife Corporation ("Unilife" or "Company") (NASDAQ: UNIS, ASX: ... will be presenting at two upcoming investor conferences taking place ... Mr. Shortall will present at the Rodman and Renshaw Annual ... On Wednesday, September 14, Mr. Shortall will present ...
Cached Medicine Technology:The Astellas European Foundation Winner of Transplantation Grant 2011 Announced 2Unilife to Participate in Two Investor Conferences 2
...
...
EDM Lumbar Drainage Kit with and without Bioglide are fabricated of radiopaque (barium impregnated) silicone tubing, and are packaged with stainless steel stylets inserted in the lumen....
Lumbar External Drainage System (LED) with Touhy needle is indicated for temporary access to the Lumbar Subarachnoid region as a means of draining cerebral spinal fluid (CSF) in order to reduce incre...
Medicine Products: