Finally, researchers looked at the cases of invasive breast cancer that arose during a mean follow-up period of 5.4 years. They assessed the relationship between rates of new invasive breast cancer cases, a family history of late-onset breast cancer, and whether either group was modified by the healthy lifestyle recommendations.
Among women with a family history who adhered to all three healthy behaviors, the rate of invasive breast cancer was 5.94 per 1,000 woman-years, compared with 6.97 per 1,000 woman-years among women who adhered to none of the behaviors, the study found.
Among women without a family history who adhered to all three healthy behaviors, the rate of invasive breast cancer was 3.51 per 1,000 woman-years compared to 4.67 per 1,000 woman-years for those who adhered to none.
The amount of risk reduced by adhering to the three health behaviors was the same for women with and without a family history.
Breast cancer is the most common form of cancer diagnosed in women, aside from non-melanoma skin cancer. About 15 percent of all postmenopausal women have a genetic predisposition to the disease.
Given the strong awareness of breast cancer and distress about inheritable risk, Gramling said, it is essential that scientists understand the actions women can take to reduce their risk.
|Contact: Leslie Orr|
University of Rochester Medical Center