Navigation Links
Breast density does not influence breast cancer death among breast cancer patients
Date:8/20/2012

The risk of dying from breast cancer was not related to high mammographic breast density in breast cancer patients, according to a study published August 20 in the Journal of the National Cancer Institute.

One of the strongest risk factors for non-familial breast cancer is elevated mammographic breast density. While women with elevated mammographic breast density have a higher risk of developing breast cancer, it is not established whether a higher density indicates a lower chance of survival in breast cancer patients.

In order to determine if higher mammographic breast density is linked to a reduced survival in breast cancer patients, Gretchen L. Gierach, Ph.D., M.P.H., of the Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute in Maryland, and colleagues looked at data from the U.S. Breast Cancer Surveillance Consortium and examined 9,232 women who were diagnosed with primary invasive breast carcinoma between 1996-2005 with an average follow-up of 6.6 years. The researchers studied the relationships between mammographic breast density and risk of death from breast cancer and all causes. Mammographic density was measured using the Breast Imaging Reporting and Data System (BI-RADS) density classification.

The researchers found that density does not influence the risk of death once the disease has developed. They write, "It is reassuring that elevated breast density, a prevalent and strong breast cancer risk factor, was not associated with risk of breast cancer death or death from any cause in this large, prospective study."

However, they did find an association between low density and increased risk of breast cancer death among obese patients, or those diagnosed with large or high-grade tumors. "One explanation for the increased risks associated with low density among some subgroups is that breasts with a higher percentage of fat may contribute to a tumor microenvironment that facilitates cancer growth and progression," the authors write.

They add that these findings highlight the need to further probe "possible interactions between breast density, other patient characteristics, and subsequent treatment in influencing breast cancer prognosis."


'/>"/>

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Related medicine news :

1. Dense Breasts Not Linked to Cancer Deaths
2. Breast-Milk Compound May Shield Babies From HIV
3. Added benefit of eribulin in breast cancer is not proven
4. Newer Bone Drug Better for Advanced Breast Cancer Patients: Study
5. New oncogene identified for breast cancer
6. Study Questions Guidelines on Radiation for Older Breast Cancer Patients
7. Protective bacteria in the infant gut have resourceful way of helping babies break down breast milk
8. Springer and the Breast Cancer Research Foundation to collaborate on book series
9. Radiation after lumpectomy helps prevent need for mastectomy in early stage breast cancer
10. Study: Majority of older, early-stage breast cancer patients benefit from radiation after lumpectomy
11. When Partner Has Breast Cancer, Men Find Their Own Ways to Cope
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... WI (PRWEB) , ... October 13, 2017 , ... As ... in medicine known as “patient engagement.” The patient is doing more than filling out ... partners. , “There is an increasing emphasis in health care and research on ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate ... primary prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided ... Piedras, Puerto Rico , where the ... Following a comprehensive onsite ... structural damage, temporary loss of power and minimal water ... manufacturing operations have resumed, and the company expects to ...
(Date:10/10/2017)... 10, 2017   West Pharmaceutical Services, Inc. ... injectable drug administration, today shared the results of a ... improving the intradermal administration of polio vaccines. The study ... in May 2017 by Dr. Ondrej Mach , ... Health Organization (WHO), and recently published in the journal ...
(Date:10/5/2017)... Ill. , Oct. 5, 2017  In ... Association of Oral and Maxillofacial Surgeons (AAOMS) released ... opioids – to be used as a first-line ... pain. Recognizing ... the AAOMS White Paper "Opioid Prescribing: Acute and ...
Breaking Medicine Technology: