Navigation Links
Breast density, no lobular involution increase breast cancer risk
Date:10/29/2010

Women with dense breasts and no lobular involution were at a higher risk for developing breast cancer than those with non-dense breasts and complete involution, according to a study published online in The Journal of the National Cancer Institute.

Apart from age, family history, and age at menarche, two additional factors associated with breast cancer risk include mammographic breast density and extent of lobular involution. Lobular involution is the physiological atrophy of the breast epithelium and is known to increase with increasing age.

To determine whether these two factors are independently associated with breast cancer risk, Karthik Ghosh, M.D., of the Mayo Clinic, and colleagues investigated the factors' association with breast cancer risk in a cohort of 2666 women with benign breast disease, followed for a mean of 13.3 years; 172 (6.5%) women subsequently developed breast cancer.

The researchers took their cohort from the larger Mayo Breast Disease cohort, which included 9376 women between the ages of 18 and 85, with no history of breast cancer, who were diagnosed with benign breast disease between 1967 and the end of 1991.

The researchers found that breast density and extent of lobular involution were independent risk factors for breast cancer, and that combined, they pose an even greater risk. The authors write: "Our findings also reveal that having a combination of dense breasts and no lobular involution was associated with higher breast cancer risk than having non-dense or fatty breasts and complete involution."

The researchers write that one of the study's strengths is that it was conducted in a large, well-organized cohort of women; however, limitations include the fact that the study population was predominantly white and representative of the upper Midwest, pointing to the need to conduct research in diverse populations.

In an accompanying editorial, Gretchen L. Gierach, Ph.D.,
'/>"/>

Contact: Kristine Crane
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

1

GOOD

Page: 1 2

Related medicine news :

1. Study Finds Green Tea Offers No Protection From Breast Cancer
2. Women Urged to Reclaim Their Life After Breast Cancer
3. Portable breast scanner allows cancer detection in the blink of an eye
4. Breast center receives RI Pink Heals donation
5. New Finding Suggests Safe Surgical Margins When Removing Breast Cancers
6. Chicago racial disparities in breast cancer mortality significantly higher than national average
7. Hormone therapy increases invasive breast cancer and mortality, WHI 11-year follow up finds
8. Researchers advocate for more education and attention regarding rare breast cancer
9. Inflammatory breast cancer focus of new report
10. Soy May Reduce Breast Cancer Recurrence: Study
11. The protein NOS2 isnt good for ER-negative breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... Palo Alto has taken yet another step in ... its recent major long-term solar power commitment. , Last ... power purchase agreements , which together will result in the ... electric power per year, which is the equivalent of roughly ... power to supply all 65,000+ Palo Alto residents---and then some! ...
(Date:6/18/2013)... New York, NY (PRWEB) June 18, 2013 ... M2a Magnum hip continue to move forward in a ... Indiana, Bernstein Liebhard LLP reports. According to court ... on June 17th, at which time the Court also ... scientific and technical issues pertinent to the Biomet hip ...
(Date:6/18/2013)... June 18, 2013 Sun Buick GMC, Moosic, ... Health Services 20th Annual Golf Tournament on Thursday, June 20, ... hole-in-one prize is a 2013 Buick Verano and will go ... a hole-in-one on Irem’s 7th hole. , The MFHS golf ... is a four person captain and crew team for 18 ...
(Date:6/18/2013)... 18, 2013 Seven-year-old Riley Salz of ... autism. He receives 40 hours a week of applied ... from the Center for Autism and Related Disorders (CARD). ... 2008, and has experienced remarkable progress, including learning to ... environment. Riley’s personal journey through autism is now featured ...
(Date:6/18/2013)... 18, 2013 Internationally acclaimed plastic ... website, thebestbreast.com, showcasing his unique approach to breast ... about his surgical method and highlights the results ... his website, Dr. Tebbetts compares his breast augmentation ... Dr. Tebbetts’ method does not necessitate the use ...
Breaking Medicine News(10 mins):Health News:Palo Alto Seals the Deal on Major Solar Electric Investments 2Health News:Palo Alto Seals the Deal on Major Solar Electric Investments 3Health News:Biomet Hip Lawsuit News: Bernstein Liebhard LLP Reports on Latest Status Conference in Federal Biomet Hip Replacement Litigation 2Health News:Biomet Hip Lawsuit News: Bernstein Liebhard LLP Reports on Latest Status Conference in Federal Biomet Hip Replacement Litigation 3Health News:June's Release of CARD's "Mission Possible: Portraits of Hope" Features Southern California Child and His Remarkable Progress with Intensive Autism Therapy 2Health News:June's Release of CARD's "Mission Possible: Portraits of Hope" Features Southern California Child and His Remarkable Progress with Intensive Autism Therapy 3Health News:Internationally Acclaimed Breast Augmentation Expert Announces the Launch of His New Website 2
... M. Miano, Ph.D associate professor within the Cardiovascular Research ... that // small regulatory DNA sequences control ... scanned the vast human DNA code to reveal 60 ... of the study were published in the journal Genome ...
... one of the National Institutes of Health has awarded ... Infectious Disease Agent Study (MIDAS) grants to // ... research team. , The goal of this ... techniques. These techniques would be used later to quickly ...
... treatment benefits with your doctor does not seems to benefit ... Colleagues, University of California, San Francisco found in a study ... and shared the decision with their doctor. ,The ... patient did not benefit the patient in deciding the symptoms ...
... has revealed that investing more money in the country’s healthcare ... necessarily// result in better services. The manner in which the ... the author of the report. The name of the report ... healthcare system in the country is available at British Columbia, ...
... for rotavirus has been approved by the US. The rotavirus ... of about 500,000 children across the world annually. // In ... medicine's maker tested the vaccine on more than 70,000 children ... ,Rotavirus is a highly contagious virus that causes severe dehydrating ...
... will be recruiting Indian nurses to overcome the shortage of ... Nursing at Medi-Clinic, told the Afrikaans daily Beeld here that ... for India to start a selection process for 60 clinical ... project in the Western Cape Province, where the shortage of ...
Cached Medicine News:Health News:Human Complexity Can Be Attributed To Regulatory Sequence 2Health News:Detecting Epidemics using statistics 2
(Date:6/18/2013)... MT. PROSPECT, Ill. , June 18, 2013 ... availability of its new X3130 Appliance Inlet Module. ... thermal circuit breaker , combines a C14 appliance ... in one compact package.  This three-in-one device allows ... in their designs - cutting installation time by ...
(Date:6/18/2013)... N.J. , June 18, 2013  Actavis, Inc. (NYSE: ... Actavis") has filed with the U.S. Securities and Exchange Commission ... Actavis, proposed acquisition of Warner Chilcott plc (NASDAQ: ... of Actavis and Warner Chilcott (the "Form S-4"). ... and Warner Chilcott have entered into a definitive ...
(Date:6/18/2013)... , June 18, 2013  It has ... of Alliance Seating and Mobility, a subsidiary company ... access timely repair. This appears to be due ... reduction of field service employees.  ... great many of these clients are complex mobility ...
Breaking Medicine Technology:Three-in-One X3130 Appliance Inlet Module 2Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 2Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 3Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 4Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 5Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 6Actavis Files Registration Statement on Form S-4 in Connection with Proposed Warner Chilcott Acquisition 7
... 21, 2010 Takeda Pharmaceutical Company Limited ("Takeda") ... Takeda Pharmaceuticals North America, Inc. ("TPNA"), have completed ... against the companies in response to their Abbreviated ... HCl), ACTO plus met® (pioglitazone HCl and ...
... Dec. 21, 2010 Today, Pepex Biomedical, Inc. announced ... $244,479.25 under the Qualifying Therapeutic Discovery Project created by ... Affordable Care Act of 2010, the major health care ... March 23, 2010.  Pepex submitted their ground-breaking, patented, electrochemical ...
Cached Medicine Technology:Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride) 2Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride) 3Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride) 4Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride) 5Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride) 6Pepex™ Awarded Qualifying Therapeutic Discovery Project Grant 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: