Navigation Links
Breast cancer tumors grow faster in younger women
Date:5/7/2008

A new approach to estimating tumour growth based on breast screening results from almost 400,000 women is published today BioMed Centrals open access journal, Breast Cancer Research. This new model can also estimate the proportion of breast cancers which are detected at screening (screen test sensitivity). It provides a new approach to simultaneously estimating the growth rate of breast cancer and the ability of mammography screening to detect tumours.

The results of the study show that tumour growth rates vary considerably among patients, with generally slower growth rates with increasing age at diagnosis. Understanding how tumours grow is important in the planning and evaluation of screening programs, clinical trials, and epidemiological studies. However, studies of tumour growth rates in people have so far been based mainly on small and selected samples. Now, Harald Weedon-Fekjr of the Department of Etiological Research, Cancer Registry of Norway and colleagues have developed a new estimating procedure to follow tumour growth in a very large population of breast cancer patients included in the Norwegian Breast Cancer Screening Program.

The researchers applied their model to cancer incidence and tumour measurement data from 395,188 women aged between 50 and 69 years old. They found that tumour growth varies considerably between subjects. About one in twenty tumours double in size in just over a month from 10 to 20mm, while similar numbers took more than six years to grow to this size. They estimated the mean time for a tumour to double in size from 10 to 20 mm in diameter is 1.7 years.

There are enormous implications for the sensitivity of breast cancer screening programs Weedon-Fekjr explains. We found that mammography screen test sensitivity (STS) increases sharply with increased tumour size, as one might expect. Detection rates are just 26% for a 5 mm tumour but increase to 91% once a tumour is 10 mm in size. The team compared their model with the previously used Markov model for tumour progression, and found its predictive power to be almost twice as accurate as the Markov model, in addition to providing new estimates directly linked to tumour size.


'/>"/>

Contact: Charlotte Webber
charlotte.webber@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related medicine news :

1. Aflac CEO Funds Breast Cancer Symposium in Honor of Companys African-American Female Employees
2. Many Ob-Gyn Textbooks Lack Good Info on Breast-Feeding
3. Breast-Feeding May Boost IQ
4. Mothers Pass Dangerous Toxins to Babies Through Breast Milk
5. Scientists identify gatekeepers of breast cancer transition to invasive disease
6. Celebrity Mothers and Daughters Including Miley and Trish Cyrus Join Swarovski to Support Breast Cancer Survivors
7. Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million
8. Second breast cancer may be greater than thought for high-risk women without BRCA mutations
9. Mothers with Breast Cancer Can Dine to Thrive with Gourmet Meal Delivery
10. Study shows gene variations may predict risk of breast cancer in women
11. Breast Enhancement With Fat: Pros and Cons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... May 03, 2016 , ... AvePoint, ... release of DocAve 6 Service Pack (SP) 7, the enterprise-class infrastructure ... 2016 and take advantage of the platform’s latest features – whether in an ...
(Date:5/3/2016)... ... May 03, 2016 , ... Branches, Inc. is proud to have been selected ... youth programs in South Miami. Macy’s is a wonderful community partner and has helped ... afterschool tutoring, mentoring, enrichment and academic support to elementary students 5 days a week. ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... Microsoft secure remote access connectivity solutions, today announced the new SecureAccess feature ... DirectAccess. The new Celestix SecureAccess release will enable organizations to get the ...
(Date:5/3/2016)... ... ... to address a patient’s condition before it worsens will ultimately lower the cost of healthcare—and ... right thing, at the right time, at the right dose with the right patient … ... FAAFP, from Group Practice Forum. “Even if the cost of the treatment might be a ...
(Date:5/3/2016)... ... May 03, 2016 , ... Hydra Skin Sciences, a top-rated ... Allegro Anti-aging Cream, a revolutionary new anti-aging skin care product that integrates ... damaged skin, has sold over seventy-five thousand units worldwide within the first two months ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... , May 3, 2016 ... Research Report provides a basic overview of the ... post which the surgical mesh report explores into ... Complete report on Surgical Mesh market ... and 98 tables and figures is available at ...
(Date:5/3/2016)... 3, 2016 Norgine ... sie einen entscheidenden Meilenstein durch diese Veröffentlichung ... zum Handeln, um Patientenresultate  bei Verdauungs- und ... Fortschritten im Verständnis der Hepatischen Enzephalopathie bei ... für Hepatische Enzephalopathie in der Öffentlichkeit zu ...
(Date:5/2/2016)... , May 2, 2016 Kalorama Information noted ... Medical Records) market in a recent white paper.  The ... Increased physician usage, a growing market are among the ... in Kalorama,s report EMR 2016: The Market ... Kalorama,s seventh complete study of the EMR industry, and ...
Breaking Medicine Technology: