Navigation Links
Breast cancer tumor make-up changes through the course of disease
Date:9/25/2011

Stockholm, Sweden: New research has found that breast cancer tumours change their hormonal status throughout the course of disease, whereas the decision about the most effective treatment for the patient is usually only based on one biopsy of the primary tumour. For some patients, biopsy verifications of any relapse will be very important because it may completely change their clinical management, a Swedish researcher will tell the 2011 European Multidisciplinary Cancer Congress [1] today (Monday 26 September). Dr. Linda Lindstrm, from the Karolinska Institutet Department of Oncology-Pathology, Solna, Stockholm, will say that her group's research is the first sizeable study to look at changes in tumours in multiple relapses in breast cancer patients.

"Our study demonstrates tumour instability in clinically used markers throughout tumour progression. We saw, for example, that one in three breast cancer patients alter oestrogen (ER) or progesterone (PR) hormone receptor status, and 15% of patients change human epidermal growth factor receptor 2, or HER2, status during the course of disease," she will say.

ER and PR receptor status tests show whether one or both of these hormones is helping to grow the cancer. Cancer that is hormone positive can be treated by hormone-suppressing drugs, whereas hormone negative cancers may respond to other types of treatment. Hormone negative patients are normally tested for HER2. If this test is positive, treatment such as Herceptin will usually be given.

The researchers studied breast cancer patients in the Stockholm healthcare region who had a recurrence of the disease between January 1, 1997 and December 31, 2007. Information on ER status in several relapses from the same individual was assessed in 119 patients: 33.6% of patients had changes in tumour status between the different sites of relapse (local, loco-regional and metastases) whereas 36.1% of the patients were stable ER positive, and 30.3%
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Zoledronic acid reduces the recurrence of breast cancer in post-menopausal women
2. Radiotherapy between or during chemotherapy cycles reduces risk of breast cancer recurrence
3. Phase II study shows new cancer drug combination significantly delays breast cancer progression
4. Study Suggests Link Between Stress and Aggressive Breast Cancer
5. Elderly breast cancer patients risk treatment discrimination
6. Virus kills breast cancer cells in laboratory
7. Error rate higher in breast imaging reports generated by automatic speech recognition
8. Too Few Uninsured Women Get Info on Breast Reconstruction
9. MRI Can Spot Breast Cancer in High-Risk Women: Study
10. Higher Risk of Second Breast Cancer Seen in Black Women
11. Can Fatty Acids in Breast Milk or Formula Make Kids Smarter?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... PITTSBURGH, PA (PRWEB) November 27, 2014 ... there are many medical precautions and procedures in place ... the handling and disposal of things tainted with menstrual ... me to design a simpler, more sanitary way to ... environment," said an inventor from Sonora, Calif. , He ...
(Date:11/27/2014)... Randy Dotinga HealthDay ... Some people,s brains seem pre-wired to acquire a second language, ... their mother tongue will likely gain a brain boost, the ... and integrated after learning," said study co-author Ping Li, co-director ... State University. But it,s even more interesting, Li said, that ...
(Date:11/27/2014)... In order to enable people to adapt to the germaphobic ... to avoid touching a toilet seat and/or lid while raising ... the patent-pending Toilet Tamer, a device that enables a user ... a more sanitary manner. It avoids direct contact with dirty ... good hygiene and peace of mind. The portable device is ...
(Date:11/27/2014)... New York, New York (PRWEB) November 27, 2014 ... behalf of individuals who were allegedly injured by the ... court, where a federal litigation is looking ahead to ... , According to a Scheduling Order issued earlier ... take place on December 16th at 10:00 a.m. Items ...
(Date:11/27/2014)... Washington, DC (PRWEB) November 27, 2014 “LAB.C” ... Report, which features the latest and coolest technology products available ... NewsWatch, conducted the product review and shared with ... cable for iOS and Android devices. , Consumers love portability ... LAB.C. Their Cable Case for the iPhone5 and 5S ...
Breaking Medicine News(10 mins):Health News:Some People May Be Pre-Wired to Be Bilingual 2Health News:Some People May Be Pre-Wired to Be Bilingual 3Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:Top Mobile Friendly Accessories were Featured on NewsWatch Television on October 30, 2014 2
... News) -- High blood pressure is associated with a steeper ... study finds. Major decreases in walking speed can affect ... problems; it may also predict who will develop dementia or ... of 643 seniors over 14 years. The participants, who were ...
... organized follow-up care for depression effectively and efficiently, according ... patients that the Journal of General Internal Medicine ... five months, compared to the half of the patients ... had three online care management contacts with a trained ...
... University of Rochester physicians and scientists that has helped ... now more widely available, thanks to approval by the ... the Rochester Nomogram, marks a leap forward for patients ... Refractive surgeon Scott MacRae, M.D., helped develop the formula ...
... Young adults are more likely to be heavy drinkers if they ... also had to cope with stressful life events, a new study ... women and 140 men in Germany who were asked about when ... the previous three years, what daily hassles they might have had ...
... Decisions about whether and how to diagnose children with ... treat them, are sometimes not clear-cut. When decisions lie ... value commitments can reach different but equally respectable conclusions. ... a special report. However, one of the report,s ...
... HealthDay Reporter , TUESDAY, March 15 (HealthDay News) -- ... cell phones while crossing the street, because new research ... than for college students. In laboratory simulations at ... to 81 and 18 undergraduates aged 18 to 26 ...
Cached Medicine News:Health News:High Blood Pressure Linked to Drop in Walking Speed, Study Finds 2Health News:Online messaging delivers follow-up care for depression 2Health News:Rochester technology to enhance eyesight approved by FDA 2Health News:Rochester technology to enhance eyesight approved by FDA 3Health News:Drinking Behavior May Be Tied to Early Alcohol Use 2Health News:Depolarizing the debates about pediatric mental health diagnosis and treatment 2Health News:Depolarizing the debates about pediatric mental health diagnosis and treatment 3Health News:Depolarizing the debates about pediatric mental health diagnosis and treatment 4Health News:Crossing Street While on Cell Phone Risky for Seniors 2
(Date:11/26/2014)... Texas , Nov. 26, 2014 ... today announced the completion of previously announced concurrent ... million.  After fees and estimated offering expenses, Lexicon ... the transactions.  The transactions consisted of: ... common stock, pursuant to a registration statement that ...
(Date:11/26/2014)...  Over 100 million adults suffer from chronic pain ... daily. Chronic and acute pain dramatically impacts quality of ... fulfill the need for non-surgical, interventional solutions and medication ... On October 28th, a new pain management center opened ... community.  This new facility boasts cutting edge technologies ...
(Date:11/26/2014)... 2014  BioScrip ® , Inc. (NASDAQ: BIOS ) ... Executive Officer, will present at the Bank of America Merrill Lynch ... , Date: , , , Wednesday, December 3, 2014 , ... , , , Location: , , , Boca Raton Resort ... Inc. BioScrip, Inc. is a leading national ...
Breaking Medicine Technology:Lexicon Announces Completion Of $280 Million In Financing Transactions 2Lexicon Announces Completion Of $280 Million In Financing Transactions 3New Pain Management Center Opens in Cumberland, Md. 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: