Navigation Links
Breast cancer screening may lower mortality and disease burden in India
Date:9/9/2008

Regular screening of women between the ages of 40 and 59 could substantially reduce breast cancer mortality in India, according to a study in the September 9 online issue of the Journal of the National Cancer Institute.

Breast cancer screening programs are regularly used in developed countries where the incidence of breast cancer is highest, and an extensive health care system is in place. The value and practicality of such screening programs in the developing world is less clear. Although the developing world has a lower breast cancer incidence rate, women tend to have more advanced disease at diagnosis and a greater risk of dying from their disease.

To estimate the ability of screening in a developing country to reduce the number of deaths and the stage of disease at diagnosis, Harry J. de Koning, M.D., Ph.D., of Erasmus Medical Center in Rotterdam, The Netherlands, and colleagues used a Microsimulation Screening Analysis model to estimate the impact of screening with clinical breast exams or mammography in India. The researchers estimated the cost-effectiveness, which is the cost of screening per life year gained, for each screening approach in international dollars (Int$), which are used by the World Health Organization and has the same purchasing power in India as a U.S. dollar does in the United States.

A single clinical breast exam for women at age 50 was estimated to reduce breast cancer mortality by 2 percent at a cost-effectiveness of Int$793 per life-year gained. If women had clinical breast exams every five years between the ages of 40 and 60, mortality reduction would increase to 8.2 percent and the cost-effectiveness would grow to Int$l,l35 per life-year gained. The investigators estimated that annual screening with clinical breast exams would lead to nearly the same mortality reduction as biennial mammography screening but at half the net cost.

"Our results indicate that every-5-year, biennial, and annual [clinical breast exams] for women aged 40-60 all lead to considerable reductions in mortality and high numbers of life years gained," the authors write. However, India and other developing countries have significant competing demands for their health care resources. Therefore, even though the breast cancer rate is increasing substantially in the developing world, implementation of a screening program is likely to be challenging.

In an accompanying editorial, Sue Moss, Ph.D., of the Institute of Cancer Research in Surrey, UK, cautions that although studies show that mammography screening can reduce breast cancer mortality, no such data exists for clinical breast exams. "Potential barriers to effective screening also include lack of necessary infrastructure and sociocultural influences on compliance," she writes. "For screening to succeed, a high level of compliance is necessary, not only with initial screening but also with referral for further investigation in those screened positive, and with treatment in those with confirmed diagnosis." Trials in the developing world indicate that this may be difficult.

A key benefit of a screening program may be to improve the overall quality of care, according to the editorialist, "but whether screening is the best means of achieving these important aims needs further exploration."


'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

Related medicine news :

1. Eating fish while pregnant, longer breastfeeding, lead to better infant development
2. Formula Samples Hinder Breast-Feeding Efforts
3. Yoplait(R) Celebrates 10th Anniversary of Save Lids to Save Lives(R) and Sustained Commitment to Fight Against Breast Cancer
4. Drug Re-Sensitizes Breast Tumors to Treatment
5. Breast Cancer Drug Not Tied to Cognitive Decline: Study
6. Hospitals provide formula sample packs while medical organizations encourage breastfeeding
7. Komen Travels to Republican Convention to Raise Awareness of Breast Cancer Issues
8. Superbug breast infections controllable in nursing mothers, UT Southwestern researchers find
9. Komen Travels to Democratic Convention in Denver to Raise Awareness of Breast Cancer Issues
10. Taking Codeine While Breast-Feeding May Harm Infant
11. Breastfeeding, other factors may affect risk of breast cancer type
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... 19, 2017 , ... Workrite Ergonomics announced this week the ... privacy panel system was designed to deliver the ideal blend of acoustic and ... provide the visual privacy required to maintain concentration levels and increase productivity. The ...
(Date:1/19/2017)... , ... January 19, 2017 , ... ... and staff members in 2017 who are passionate about making a difference in ... 1994 and headquartered in Tampa, UMA, a nonprofit healthcare educational institution, has more ...
(Date:1/19/2017)... ... January 19, 2017 , ... Allegheny Health Network (AHN) ... who seek access to the Network’s programs and services in the greater Pittsburgh region. ... care appointments will be offered one for that same afternoon. , AHN ...
(Date:1/19/2017)... ... , ... Sam & Associates Insurance Agency, a full service firm providing asset ... Bay Area, is launching a charity drive to raise awareness of heart disease risk ... primary killer of adult men and women in America, and is responsible for over ...
(Date:1/19/2017)... ... January 19, 2017 , ... Rountree Brady Insurance Agency, a ... throughout eastern Georgia, is embarking on a charity effort to raise awareness and ... Americans every year than anything else, yet risk factors associated with heart disease ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , January 19, 2017 According to ... for cryotherapy is set to witness a CAGR of 6.5% during ... America will continue to be the leading market for ... ... Suppliers are emphasizing on ensuring affordable and adequate supply of gas ...
(Date:1/19/2017)... 2017 Accuray Incorporated (Nasdaq: ARAY ... continue to set the bar for excellence in customer ... user satisfaction rating among radiation treatment delivery systems in ... Market Intelligence Briefing™. The most recent ratings trend also ... industry peers for 11 of the past 12 quarters. ...
(Date:1/19/2017)... Calif. , Jan. 19, 2017  Abaxis, Inc. ... manufacturing point-of-care blood analysis instruments and consumables for the ... call to discuss its financial results for the third ... call will be at 4:15 p.m. ET on Thursday, ... for the third quarter fiscal year 2017 after the ...
Breaking Medicine Technology: