Navigation Links
Breast cancer more aggressive among obese women
Date:3/13/2008

PHILADELPHIA Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese, according to findings published in the March 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.

The more obese a patient is, the more aggressive the disease, said Massimo Cristofanilli, MD, associate professor of medicine in the Department of Breast Medical Oncology at The University of Texas M.D. Anderson Cancer Center. We are learning that the fat tissue may increase inflammation that leads to more aggressive disease.

Cristofanilli and colleagues observed 606 women with locally advanced breast cancer. These women were classified by body mass index into the following three groups: normal/underweight (24.9 or below), overweight (at least 25 but less than 30) or obese (more than 30). Body mass index is calculated by dividing a persons weight by their height.

At five years, overall survival was 56.8 percent among obese women, 56.3 percent among overweight women and 67.4 percent among normal weight women. The 10-year survival rate was 42.7 percent among obese women, 41.8 percent among overweight women and 56.5 percent among normal weight women.

The rate of inflammatory breast cancer, previously shown to have worse outcomes than non-inflammatory breast cancer, among obese women was 45 percent compared with 30 percent in overweight women and only 15 percent in women considered normal weight, researchers found.

Risk of breast cancer recurrence was also higher in obese or overweight women. By five years, 50.8 percent of obese women reported a recurrence compared with 38.5 percent of normal weight women. By 10 years, the rate of recurrence was 58 percent among obese women and 45.4 percent among normal weight women.

Obesity goes far beyond just how a person looks or any physical strain from carrying around extra weight. Particular attention s
'/>"/>

Contact: Jeremy Moore
jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Survival differences by race most apparent in advanced stages of breast cancer
2. MRI finds breast cancer before it becomes dangerous
3. Pathway links inflammation, angiogenesis and breast cancer
4. Drop in breast cancer incidence linked to hormone use, not mammograms
5. Breast cancer prevention practices vary across Canada
6. Eating junk food whilst pregnant and breastfeeding may lead to obese offspring
7. Acrylamide Wont Raise Breast Cancer Risk
8. New link between estrogen and breast cancer
9. Hypnosis Eases Pain of Breast Cancer Surgery
10. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
11. Longaberger Expands Horizon of Hope Campaign to Build Support for American Cancer Societys Breast Cancer Initiatives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... -- U.S. heart experts recommend doctors use a 14-point ... people for underlying heart disease that could result in ... the American College of Cardiology said in a joint ... history along with a physical examination can help identify ... risks for sudden cardiac death. The statement, ...
(Date:9/15/2014)... (PRWEB) September 16, 2014 “Canada ... market data on the Canada Gynecological Devices market. ... dollars, volume (in units) and average prices (in ... Female Sterilization Devices (Transcervical Sterilization Devices ... Rings) , Endometrial Ablation Devices (Thermal ...
(Date:9/15/2014)... HealthDay Reporter MONDAY, ... about twice as often as they,re actually needed for ... indicates. More than 11 million antibiotic prescriptions written ... according to researchers from University of Washington and Seattle ... to eradicate children,s viral illnesses, researchers said, but supports ...
(Date:9/15/2014)... 2014 As Colorado's historic experiment ... first full year, there are a variety of ... the evolution of its marketing and branding. , ... by Denver's Kindman, one of the state's most ... Kindman has pioneered the first-ever branded and pre-packaged ...
(Date:9/15/2014)... Physicians and clinicians from around ... at the Lowes Coronado Bay Resort for the ... . This CME accredited medical conference ... healthcare professionals—about the nutritional science that overwhelmingly supports ... its proven ability to prevent, suspend and, often, ...
Breaking Medicine News(10 mins):Health News:Heart Docs Don't Recommend Routine ECGs for Young Athletes 2Health News:Heart Docs Don't Recommend Routine ECGs for Young Athletes 3Health News:Canada Gynecological Devices Market Outlook to 2020 in New Report Available at MarketOptimizer.org 2Health News:Canada Gynecological Devices Market Outlook to 2020 in New Report Available at MarketOptimizer.org 3Health News:Canada Gynecological Devices Market Outlook to 2020 in New Report Available at MarketOptimizer.org 4Health News:Kids Prescribed Antibiotics Twice as Often as Needed, Study Finds 2Health News:Kids Prescribed Antibiotics Twice as Often as Needed, Study Finds 3Health News:Colorado Company Unveils Innovative Line of Pre-packaged Cannabis Products 2Health News:Colorado Company Unveils Innovative Line of Pre-packaged Cannabis Products 3Health News:San Diego Plays Host This Week to International Plant-based Nutrition Healthcare Conference Featuring Drs. Ornish, Esselstyn, Campbell and Other Leading Experts 2Health News:San Diego Plays Host This Week to International Plant-based Nutrition Healthcare Conference Featuring Drs. Ornish, Esselstyn, Campbell and Other Leading Experts 3
... the European Journal of Cancer Care has shown that children ... of leukemia . ,As part of their study, researchers ... sophisticated meta-analysis of 17 research papers covering 136 nuclear sites ... Spain. ,Findings revealed that death rates for children ...
... without a Chinese link. Following reports of botulism outbreak, hot ... withdrawn in USA. ,This is the first ... decades. ,Health officials asked consumers and stores to ... and Austex . ,Two Texas children and an ...
... major crackdown on them, erring doctors and ... million for rorting the federal health system, since ... Service Review, (PSR) which investigates and punishes health practitioners ... (PBS) drugs inappropriately, carried out the search. ...
... James Mullen is not a happy man. The Cambridge biotechnology ... to use its drug Tysabri to treat patients with ... from drug trials that were included in an application to ... need more development". Now, an additional clinical trial proposed ...
... that a particular genetic variation may be tied to ... ,Known medically as premenstrual dysphoric disorder, or PMDD, ... in their childbearing years. It's characterized by bouts of ... second half of the menstrual cycle. These symptoms settle ...
... Researchers have revealed that combining a non-pyrethroid insecticide, ... to be an effective insecticide-repellent synergy against ... ,A combination of the two had proved ... addition of their respective properties. Mosquito nets soaked ...
Cached Medicine News:Health News:People Living Near Nuke Facilities at Higher Risk of Leukemia 2Health News:Chilly Sauce Linked to Botulism, Forcing Recall in US 2Health News:Chilly Sauce Linked to Botulism, Forcing Recall in US 3Health News:Rorting Health Practioners Busted 2Health News:MS Drug Fails The Test For Treating Crohns Disease 2Health News:Genetic Variation may Increase Premenstrual Depression Risk 2Health News:Genetic Variation may Increase Premenstrual Depression Risk 3Health News:Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes 2
(Date:9/15/2014)... HONOLULU , Sept. 15, 2014  Patients in ... specialty care more frequently in an outpatient setting versus ... the curve and to ensure that patients continue to ... today the launch of its new internal medicine residency ... practice more often in office, clinic and even virtual ...
(Date:9/15/2014)... , Sept. 15, 2014 /PRNewswire-iReach/ -- Asthma ... persons of all ages, but most commonly starts ... characterized by narrowing of the airways, leading to ... lungs come into contact with endogenous and exogenous ... events, such as swelling of the airways, tightening ...
(Date:9/15/2014)... 15, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... owned subsidiary, Valeant Pharmaceuticals International, will redeem all of ... 6.75% Senior Notes due 2017, CUSIP Nos. 91911XAL8, U9098VAD4 ... has mailed an irrevocable notice of redemption for the ... of the irrevocable notice of redemption with respect to ...
Breaking Medicine Technology:Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 2Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 3Asthma Market to Reach 161.02 million Cases in 10MM by 2023 2Asthma Market to Reach 161.02 million Cases in 10MM by 2023 3Asthma Market to Reach 161.02 million Cases in 10MM by 2023 4Asthma Market to Reach 161.02 million Cases in 10MM by 2023 5Valeant Announces Redemption of All of the Outstanding $500.0 Million Aggregate Principal Amount of its 6.75% Senior Notes due 2017 2
... Bard® Biopsy Instrument and Needle is specially ... goal: a large quality, reliable core sample. ... featuring ultra-sharp tips and polished surfaces for ... of biopsy systems and needle sizes assures ...
... to bring efficiency and quality to routine ... superior technology of fluorescent flow cytometry with ... sampling or batch processing are easily accommodated ... in high volume laboratories. Fluorescent flow ...
... The iQ200 System incorporates the ... and the AUTION MAX™ AX-4280 Automated ... a fully integrated chemical and microscopic ... (APR™), a well trained neural network, ...
... UF-100 is designed to bring efficiency and ... It combines the superior technology of fluorescent ... analysis. Continuous sampling or batch processing ... streamlining sample processing in high volume laboratories. ...
Medicine Products: