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Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
Date:5/16/2012

ancer as well as limiting its ability to spread."

The mice in Hyder's study were injected with apigenin. In the future, apigenin injections could be a safe alternative or supplement to the highly toxic chemotherapy drugs now in use.

"Chemotherapy drugs cause hair-loss, extreme fatigue and other side effects," Hyder said. "Apigenin has shown no toxic side-effects even at high dosages. People have eaten it since pre-history in fruits and vegetables."

Finding funding for clinical testing of apigenin in humans may be difficult, according to Hyder.

"Clinical trials of apigenin with humans could start tomorrow, but we have to wait for medical doctors to carry out that next step," Hyder said. "One problem is, because apigenin doesn't have a known specific target in the cancer cell, funding agencies have been reticent to support the research. Also, since apigenin is easily extracted from plants, pharmaceutical companies don't stand to profit from the treatment; hence the industry won't put money into studying something you can grow in your garden."

The research team included Benford Mafuvadze, doctoral student in biomedical sciences; Yanyun Liang, research scientist Dalton Cardiovascular Research Center; Cynthia Besch-Williford, associate professor of veterinary pathobiology; and Xu Zhang, visiting researcher at the Dalton Cardiovascular Research Center.

The research was recently published online in the journal Hormones and Cancer.


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Contact: Timothy Wall
walltj@missouri.edu
573-882-3346
University of Missouri-Columbia
Source:Eurekalert

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