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Breast cancer diagnosis, mammography improved by considering patient risk: INFORMS paper
Date:6/17/2014

plored profile information and potential bias in mammography interpretation using a decision science technique called linear opinion pooling, which assigns weights to better aggregate probability estimates.

They analyzed the decision performance of three groups: (1) a mammogram-only reading, with no risk profile information about the patient, (2) an unbiased reading, in which radiologists consult the risk profile after examining the mammogram and (3) biased or "influenced" readings, in which radiologists consult a woman's risk profile as they examine the mammogram. Then they examined the conditions in which profile information could help improve biopsy decisions.

Numerical analysis using a clinical dataset from the Breast Cancer Surveillance Consortium revealed that use of profile information with an appropriate weight could reduce the false positives and the number of missed cancers when compared to cases where profile information was not examined.

Breast cancer is the second most deadly non-skin cancer. In 2013, approximately 232,000 breast cancer diagnoses were made and about 39,000 women died from the disease.


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Contact: Barry List
barry.list@informs.org
443-794-5182
Institute for Operations Research and the Management Sciences
Source:Eurekalert

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