Navigation Links
Breast Cancer's Return in Original Tumor Site a Bad Sign
Date:3/24/2010

Such cases are few after time, but death risk is then much higher, researchers say

WEDNESDAY, March 24 (HealthDay News) -- Breast cancer recurrence in the same area as the original tumor is a strong, independent predictor of subsequent cancer spread and death in patients who've been cancer-free for a long time, a new study has found.

Researchers analyzed data from 7,749 European women treated with breast-conserving treatment for early-stage breast cancer. The women were followed for an average of 10.9 years.

The study found that cancer recurrence in the same area as the original cancer (locoregional recurrence) was the most important prognostic factor after a disease-free period of five years, and the sole independent prognostic factor after a disease-free period of 10 years.

"In patients who were free of disease for more than 10 years after primary treatment, locoregional recurrence had a significant impact on both disease-free survival and overall survival," Dr. Sven Mieog, a research fellow at Leiden University Medical Center in the Netherlands, said in a news release from the European Breast Cancer Conference.

"The increased risk of metastases [cancer spread] after a recurrence was approximately four times higher than if there had been no recurrence, and the risk of dying after a recurrence was around eight times higher. However, these levels of increased risk need to be treated with caution because, with the longer time interval between the primary cancer and the recurrence, the number of events goes down, making these calculations less certain, although they remain important for clinicians when deciding on the best treatments," Mieog said.

The findings were to be presented Wednesday at the European Breast Cancer Conference in Barcelona.

"The fact that locoregional recurrence is still a very strong prognostic factor, even after a long disease-free interval, suggests that it probably is a symptom of (and therefore associated with) distant disease occurring at the same time, and not the instigator of disease progression in the majority of cases," study collaborator Dr. Jos A. van der Hage, a surgical oncologist at the Netherlands Cancer Institute in Amsterdam, said in the news release.

More information

Breastcancer.org has more about recurrent and metastatic breast cancer.



-- Robert Preidt



SOURCE: European Breast Cancer Conference, news release, March 24, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Worse breast cancer outcomes for women from poorer backgrounds are not due to late diagnosis alone
2. Recurrence of breast cancer after more than 10 years is an important indicator of survival
3. What should be the goal of treatment in metastatic breast cancer?
4. Fertility issues in young women with breast cancer must be addressed
5. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
6. IPhone App is New Tool in the Fight Against Breast Cancer
7. Newer Genetic Info Adds Little to Predicting Breast Cancer
8. Case managers help low-income women receive more timely breast cancer diagnosis
9. Freezing Tumors Shows Promise Against Prostate, Breast Cancer
10. Palpable breast cancers are more common in women not undergoing annual mammography
11. Dr. Kevin Nini to Lead Reconstructive Breast Surgery Program at Hunterdon Regional Cancer Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... ... “Fruit of the Spirit: “Love””: a delightful adventure of two friends who play ... Spirit: “Love”” is the creation of published author, Halimah Jones, who was born and ... an avid writer, her inspiration for “Fruit of the Spirit: “Love”” blossomed from her ...
(Date:9/22/2017)... ... September 22, 2017 , ... Global Lyme Alliance (GLA), ... education and awareness, today announced the appointment of Timothy J. Sellati, Ph.D. as ... has more than 20 years of research experience with Lyme and other tick-borne ...
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... SABRE is ... run from September 11 to the end of November. , The Chicago, Illinois, based ... their community and teach them about the ease of taking their personal safety into ...
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... ... in their communities, nine governmental public health departments have been awarded five-year accreditation ... decisions mean that the benefits of being served by a PHAB-accredited health ...
(Date:9/21/2017)... ... September 21, 2017 , ... The New England Center for ... today the election of Yie-Hsin Hung to the Board of Directors. , “The ... of Directors. Ms. Hung is an invaluable addition to our team,” said Vincent Strully, ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... -- NeuroRx, a clinical stage biopharma company developing the first ... been granted Fast Track status by the US Food and ... followed by NRX-101 (D-cycloserine + lurasidone). The company will shortly ... therapy targeting patients who are admitted to Emergency Departments with ... ...
(Date:9/5/2017)... N.J. , Sept. 5, 2017  Getinge, ... has created a vibrant charitable donation program -- ... and support congenital heart defect research by The ... providers and the general public are encouraged to ... and submit the completed artwork to the gallery ...
(Date:9/1/2017)... Like Us ( https://explorerslikeus.com/ ) is embarking on "An American ... these experiences as part of Life Environments™, a new technology ... ... beats a walk, jog or simply playing in a garden ... next best thing when getting there isn’t possible. Life Environments™ ...
Breaking Medicine Technology: