Navigation Links
Breast Cancer's Return in Original Tumor Site a Bad Sign
Date:3/24/2010

Such cases are few after time, but death risk is then much higher, researchers say

WEDNESDAY, March 24 (HealthDay News) -- Breast cancer recurrence in the same area as the original tumor is a strong, independent predictor of subsequent cancer spread and death in patients who've been cancer-free for a long time, a new study has found.

Researchers analyzed data from 7,749 European women treated with breast-conserving treatment for early-stage breast cancer. The women were followed for an average of 10.9 years.

The study found that cancer recurrence in the same area as the original cancer (locoregional recurrence) was the most important prognostic factor after a disease-free period of five years, and the sole independent prognostic factor after a disease-free period of 10 years.

"In patients who were free of disease for more than 10 years after primary treatment, locoregional recurrence had a significant impact on both disease-free survival and overall survival," Dr. Sven Mieog, a research fellow at Leiden University Medical Center in the Netherlands, said in a news release from the European Breast Cancer Conference.

"The increased risk of metastases [cancer spread] after a recurrence was approximately four times higher than if there had been no recurrence, and the risk of dying after a recurrence was around eight times higher. However, these levels of increased risk need to be treated with caution because, with the longer time interval between the primary cancer and the recurrence, the number of events goes down, making these calculations less certain, although they remain important for clinicians when deciding on the best treatments," Mieog said.

The findings were to be presented Wednesday at the European Breast Cancer Conference in Barcelona.

"The fact that locoregional recurrence is still a very strong prognostic factor, even after a long disease-free interval, suggests that it probably is a symptom of (and therefore associated with) distant disease occurring at the same time, and not the instigator of disease progression in the majority of cases," study collaborator Dr. Jos A. van der Hage, a surgical oncologist at the Netherlands Cancer Institute in Amsterdam, said in the news release.

More information

Breastcancer.org has more about recurrent and metastatic breast cancer.



-- Robert Preidt



SOURCE: European Breast Cancer Conference, news release, March 24, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Worse breast cancer outcomes for women from poorer backgrounds are not due to late diagnosis alone
2. Recurrence of breast cancer after more than 10 years is an important indicator of survival
3. What should be the goal of treatment in metastatic breast cancer?
4. Fertility issues in young women with breast cancer must be addressed
5. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
6. IPhone App is New Tool in the Fight Against Breast Cancer
7. Newer Genetic Info Adds Little to Predicting Breast Cancer
8. Case managers help low-income women receive more timely breast cancer diagnosis
9. Freezing Tumors Shows Promise Against Prostate, Breast Cancer
10. Palpable breast cancers are more common in women not undergoing annual mammography
11. Dr. Kevin Nini to Lead Reconstructive Breast Surgery Program at Hunterdon Regional Cancer Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2016)... ... December 03, 2016 , ... "Perfect Harmony comes with ... allowing FCPX editors to create professional looking video in a matter of minutes," ... contains a beautifully designed 3D environment for placing in personal media. Twenty pre-made ...
(Date:12/4/2016)... Aliso Viejo, California (PRWEB) , ... December 04, ... ... self-animating lower third presets that have new attractive animation styles with unique displacement ... Pro3rd Displace features 30 pre-animated lower third designs. Choose from a variety of ...
(Date:12/2/2016)... ... December 02, 2016 , ... Halfway through its partnership with First 5 ... services to more than 15,900 children 5 years old and younger and treatment services ... over a span of five years to Western University of Health Sciences, UCLA and ...
(Date:12/2/2016)... ... 02, 2016 , ... For over twenty-four years, Doctors on Liens has published a ... find high quality medical care. When the company started in 1997, the directory was ... present day and the now ten-page directory features a vast array of medical specialists ...
(Date:12/2/2016)... ... ... Center for Autism and Related Disorders (CARD) Portland today announced plans to ... and other developmental disabilities. The group, which is being launched with the help of ... to share stories and advice, seek help, and continue their education on how to ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... December 2, 2016 On Thursday, ... honored excellence in research, development and innovation in the ... dinner was held in the presence of Sergey Tsyb, ... Russian Federation , Natalia Sanina, First Vice ... Murashko , Head of Roszdravnadzor, National Service of Control ...
(Date:12/2/2016)... Columbia , December 2, 2016 bioLytical Laboratories, ... INSTI HIV-Selbsttest, bei den Mitgliedern des Apothekenbundes von Kenia eingeführt. ... ... INSTI HIV Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) ...
(Date:12/2/2016)... 2, 2016 Lianluo Smart Limited (Nasdaq: ... Company") which develops, markets and sells medical devices ... China and international markets, recently attended ... Treatment New Progress Forum, co-hosted by the Institute ... , Guangdong Provincial People,s Hospital and Cardiology ...
Breaking Medicine Technology: