Navigation Links
Breast Cancer's Return in Original Tumor Site a Bad Sign
Date:3/24/2010

Such cases are few after time, but death risk is then much higher, researchers say

WEDNESDAY, March 24 (HealthDay News) -- Breast cancer recurrence in the same area as the original tumor is a strong, independent predictor of subsequent cancer spread and death in patients who've been cancer-free for a long time, a new study has found.

Researchers analyzed data from 7,749 European women treated with breast-conserving treatment for early-stage breast cancer. The women were followed for an average of 10.9 years.

The study found that cancer recurrence in the same area as the original cancer (locoregional recurrence) was the most important prognostic factor after a disease-free period of five years, and the sole independent prognostic factor after a disease-free period of 10 years.

"In patients who were free of disease for more than 10 years after primary treatment, locoregional recurrence had a significant impact on both disease-free survival and overall survival," Dr. Sven Mieog, a research fellow at Leiden University Medical Center in the Netherlands, said in a news release from the European Breast Cancer Conference.

"The increased risk of metastases [cancer spread] after a recurrence was approximately four times higher than if there had been no recurrence, and the risk of dying after a recurrence was around eight times higher. However, these levels of increased risk need to be treated with caution because, with the longer time interval between the primary cancer and the recurrence, the number of events goes down, making these calculations less certain, although they remain important for clinicians when deciding on the best treatments," Mieog said.

The findings were to be presented Wednesday at the European Breast Cancer Conference in Barcelona.

"The fact that locoregional recurrence is still a very strong prognostic factor, even after a long disease-free interval, suggests that it probably is a symptom of (and therefore associated with) distant disease occurring at the same time, and not the instigator of disease progression in the majority of cases," study collaborator Dr. Jos A. van der Hage, a surgical oncologist at the Netherlands Cancer Institute in Amsterdam, said in the news release.

More information

Breastcancer.org has more about recurrent and metastatic breast cancer.



-- Robert Preidt



SOURCE: European Breast Cancer Conference, news release, March 24, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Worse breast cancer outcomes for women from poorer backgrounds are not due to late diagnosis alone
2. Recurrence of breast cancer after more than 10 years is an important indicator of survival
3. What should be the goal of treatment in metastatic breast cancer?
4. Fertility issues in young women with breast cancer must be addressed
5. Scott & White Healthcare researchers studying investigational agent that targets breast cancer
6. IPhone App is New Tool in the Fight Against Breast Cancer
7. Newer Genetic Info Adds Little to Predicting Breast Cancer
8. Case managers help low-income women receive more timely breast cancer diagnosis
9. Freezing Tumors Shows Promise Against Prostate, Breast Cancer
10. Palpable breast cancers are more common in women not undergoing annual mammography
11. Dr. Kevin Nini to Lead Reconstructive Breast Surgery Program at Hunterdon Regional Cancer Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... or dementia. However, many long-term care insurance companies have a waiver for care if ... the 90-day elimination period, when the family pays for care, is often waived, so ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a ... health care, have expanded their existing home health joint venture through an agreement, ... been operating a joint venture home health company with Asante, delivering clinically integrated ...
(Date:10/12/2017)... Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... is holding a treadmill relay – Miles by Moonlight to raise money for the ... donating $300 or more. , Teams will work together to keep their treadmills ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- The Rebound mobile app is poised to become a ... of prescription drug addiction. The app empowers users to develop ... down their dosage in a safe, controlled manner while maximizing ... first 100,000 people to sign up will enjoy 3 months ... ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
Breaking Medicine Technology: