Navigation Links
Breast Cancer's DNA Yields More Secrets
Date:7/29/2010

By Jenifer Goodwin
HealthDay Reporter

THURSDAY, July 29 (HealthDay News) -- The genetic makeup of breast cancer tumors may be a better predictor of how well a woman will fare than a tumor's size and appearance, which has been the traditional way of looking at cancers, new research suggests.

A European team of researchers analyzed the genetic makeup of 595 breast cancer tumors and compared the results to non-cancerous breast tissue. They then used algorithms to separate the tumors into eight types based on changes in the structure of the chromosomes, including deletions or amplifications of DNA, the study authors said.

In doing so, researchers showed that certain alterations in the patterns of DNA were able to predict cancer prognosis and response to particular treatments.

These findings join a host of recent scientific discoveries that suggest that the key to thwarting breast cancer may lie in the tumor's DNA.

"Is this going to go into clinical practice tomorrow? No," said Dr. Daniel Silver, assistant professor of medicine at the Dana-Farber Cancer Institute in Boston. "This is just one step of many toward a deeper understanding of breast cancer."

The study was published in a recent issue of Science Translational Medicine.

Over the past few years, oncologists have increasingly relied on analyses of the DNA of breast cancer cells to determine which cancers are most likely to respond to certain treatments and which have the greatest chances of recurrence, explained Dr. Stephen Sener, past president of the American Cancer Society and a chief of the division of surgical oncology at the University of Southern California's Keck School of Medicine.

"For many years, until about the turn of this century, breast cancer was thought to be one basic disease," Sener said. "But since the human genome was elucidated, now people are working on the breast cancer genome. We're learning a lot more abo
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Male breast cancer in family leads to high perception of risk, low likelihood of genetic counseling
2. Genetic Risk Score Can Predict Odds For Breast Cancer
3. CIHR team grant to fund multidisciplinary breast cancer survivorship studies
4. OHSU Knight Cancer Institute researchers isolate importance of gene in breast cancer prognosis
5. FDA Advisers Say Avastin Shouldnt Be Used for Breast Cancer
6. Breast cancer cells regulate multiple genes in response to estrogen-like compounds
7. Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women
8. Prediction tool helps estimate local recurrence in patients with noninvasive breast cancer
9. Experts Issue New Guidelines on Breast Cancer Drugs
10. Radiation device allows for targeted breast radiation to control cancer
11. Scientists reprogram triple-negative breast cancer cells to respond to tamoxifen
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer's DNA Yields More Secrets
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... Model Compliance Guidance , , ... Compliance Association (HCCA) announced today that it will hold ... in Scottsdale, Arizona. The HCCA,s Managed Care Compliance conference, ... to provide essential information for individuals involved with managing ...
... Calif., Dec. 4 Microchip Biotechnologies, a private company ... announced today that Ezra Van Gelder has joined its ... , Ezra Van Gelder brings ... development from the life science, medical device and semiconductor ...
... LAKE CITY, Dec. 4 The Ensign Group, Inc.,(Nasdaq: ... Ensign(TM) group of skilled nursing,rehabilitative care services and assisted ... of Infinia at Alta, an 85-bed skilled,nursing facility in ... Alta,Care & Rehabilitation Center. , ...
... can become,stressful for many families -- the pressure to find ... and co-workers, and, this,year, the added weight of a slumping ... give the gift of companionship and joy by putting a ... "Before giving a furry friend as a gift, ...
... Drs. Samuel and Elenore Bogoch of Oncolab, Inc. have found that ... proteins*, are quantitatively related to the mortality rate in human cancer ... been reported to be quantitatively related to mortality rate. , ... ...
... Wash., Dec. 4 In the midst of ... challenges in the United States,healthcare providers from across ... corporate headquarters in Redmond, Wash., for the first ... examining,ways to apply information technology (IT) innovations to ...
Cached Medicine News:Health News:HCCA Announces Managed Care Compliance Conference, February 22-24, 2009, Scottsdale, Arizona 2Health News:HCCA Announces Managed Care Compliance Conference, February 22-24, 2009, Scottsdale, Arizona 3Health News:Ezra Van Gelder Joins Microchip Biotechnologies as Executive Vice President R&D 2Health News:The Ensign Group, Inc. Acquires Utah Skilled Nursing Facility 2Health News:A Season of Responsibility for New Pet Owners 2Health News:Cancer Mortality Increases With Cancer Cell Replikin Count 2Health News:Cancer Mortality Increases With Cancer Cell Replikin Count 3Health News:Microsoft, Penn State Hershey Medical Center Showcase Road Map to Patient Flow Efficiencies at First Healthcare Provider Symposium 2Health News:Microsoft, Penn State Hershey Medical Center Showcase Road Map to Patient Flow Efficiencies at First Healthcare Provider Symposium 3Health News:Microsoft, Penn State Hershey Medical Center Showcase Road Map to Patient Flow Efficiencies at First Healthcare Provider Symposium 4
(Date:12/17/2014)... -- Revenue and earnings above the previous year ... In the past 2013/14 fiscal year (ended 30 ... EUR 4.287 billion (last year: EUR 4.190 billion) despite unfavorable ... 360 million. "Overall, 2013/14 was a successful fiscal year for ... and CEO of Carl Zeiss AG. "Thanks to our broad ...
(Date:12/17/2014)...  Beamz Interactive, Inc. (OTCQB: BZIC), a leading ... that it has signed an agreement with RSL ... innovative prosthetic, orthotic and assistive technology products and ... RSL Steeper will promote and supply the Beamz ... within UK residential care facilities through its Assistive ...
(Date:12/17/2014)... , Dec. 17, 2014  RXi Pharmaceuticals Corporation ... focused on discovering, developing and commercializing innovative therapies ... today announced completion of enrollment in its first Phase ... 3-month observations confirmed the 1-month findings that were ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO , ...
Breaking Medicine Technology:ZEISS Asserts its Position in Difficult Environment 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 2RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 4RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 5
... 2010 Phytomedics, Inc., a transformational healthcare company ... products solely derived from plant sources, announced today ... the amount of $244,000 under the Qualifying Therapeutic ... of its lead product PMI-001 for Rheumatoid Arthritis. ...
... Nov. 9, 2010 NewCardio, Inc. (OTC Bulletin Board: ... announced today that Dr. Samuel George, NewCardio,s Senior Medical ... a blinded "testing" dataset, conducted independently by the Cardiac ... to be held on December 9, 2010, at the ...
Cached Medicine Technology:Phytomedics, Inc. Awarded QTDP Grant from U.S. Department of Health and Human Services 2NewCardio to Present Results of QTinno Performance on Cardiac Safety Research Consortium Blinded 'Testing' Dataset 2NewCardio to Present Results of QTinno Performance on Cardiac Safety Research Consortium Blinded 'Testing' Dataset 3NewCardio to Present Results of QTinno Performance on Cardiac Safety Research Consortium Blinded 'Testing' Dataset 4
... lathing techniques, intrinsically permeable polymers and advanced ... thickness of just 0.08 across all minus ... lenses maintain a 30% decrease in center ... eliminates stress points to reduce the chance ...
An easy-to-fit RGP daily wear lens with a unique bi-aspheric back surface design that provides excellent patient comfort and adaptation. Boston Envision contact lenses are an ideal alternative for vi...
Ophthalmic surgery stretcher. Designed for exceptional surgeon access, ideal for either superior or temporal approach....
... developed to stain intraocular membranes in vitreoretinal ... By injecting Membraneblue in an air-filled vitreous ... diluting the dye. After removal of all ... membranes can easily be distinguished from the ...
Medicine Products: