Navigation Links
Breast Cancer Vaccine Blasts Some Tumors
Date:9/15/2008

In animal studies, it eliminated aggressive growths

MONDAY, Sept. 15 (HealthDay News) -- An experimental breast cancer vaccine eliminated tumors in laboratory animals and may someday help prevent cancer recurrence or help treat women with treatment-resistant forms of breast cancer.

"The results were striking," said study author Dr. Wei-Zen Wei, a professor of immunology and microbiology at the Karmanos Cancer Center at Wayne State University. The research was published in the Sept. 15 issue of Cancer Research.

Wei's vaccine targets HER2-positive tumor cells. These breast cancers are often more aggressive than other types of cancer, are less responsive to treatment with hormones, and can become resistant to treatment.

On a cellular level, HER2 receptors promote normal cell growth, Wei explained. They are found in low amounts in normal breast cells, but HER2-positive breast cells can have many more receptors, and that in turn can promote the growth of an aggressive type of tumor.

Even therapies such as Herceptin (trastuzumab), designed to hook up with these receptors and destroy them, sometimes work only for a short period of time, after which patients develop a resistance, and the drug stops working.

Enter the study of Wei's vaccine, which includes "naked" DNA, genes that produce the HER2 receptor, and an immune system stimulant. When she delivered the vaccine into the leg muscles of mice with HER2-positive tumors, the gene made a huge supply of HER2 receptors that activated the immune system.

After the injection, "the body is making in this one location a lot of HER2," she said. The immune system kicks in and mounts an attack against the HER2-positive receptors, she found.

''None of them grew tumors," Wei said. That was true whether or not the tumor cells had grown drug-resistant or not.

The investigational vaccine, one of several under study for breast cance
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Risk of breast cancer mutations underestimated for Asian women, Stanford study shows
2. Pennsylvania Breast Cancer Coalition Hosts Annual Conference
3. Breast cancer screening may lower mortality and disease burden in India
4. Eating fish while pregnant, longer breastfeeding, lead to better infant development
5. Formula Samples Hinder Breast-Feeding Efforts
6. Yoplait(R) Celebrates 10th Anniversary of Save Lids to Save Lives(R) and Sustained Commitment to Fight Against Breast Cancer
7. Drug Re-Sensitizes Breast Tumors to Treatment
8. Breast Cancer Drug Not Tied to Cognitive Decline: Study
9. Hospitals provide formula sample packs while medical organizations encourage breastfeeding
10. Komen Travels to Republican Convention to Raise Awareness of Breast Cancer Issues
11. Superbug breast infections controllable in nursing mothers, UT Southwestern researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer Vaccine Blasts Some Tumors
(Date:12/19/2014)... It’s very easy to become overwhelmed with the ... to the wayside until Christmas and the New Year are ... and that burning desire to just escape it all and ... to Telluride with a no-fuss, affordable package. Montrose Days Inn ... resort, and ensure that all accommodations are met. Plus, everyone ...
(Date:12/19/2014)... Energy Textiles is excited to ... Celliant, the world’s leading responsive textile, can now ... There are a number of benefits to wearing ... and balanced body temperature; which can lead to ... enhanced athletic performance; and overall wellness. In addition, ...
(Date:12/19/2014)... 19, 2014 SuperCloset raises the bar ... SuperCloset continues to offer indoor growers the most efficient ... the new SuperClone Rooms with the award winning ... indoor hydroponic grow room setup. , The SuperClone Room ... SuperPonic SuperCloner 50 . The SuperClone ...
(Date:12/19/2014)... 2014 An evening dress is perfect for ... closet. Discount-Dress.com, a distinguished dresses retailer, has unveiled its new ... in this great shopping platform. Customers can view ... hard work, Discount-Dress.com has been accepted and praised by customers ... easier shopping stage for clients. In order to expand its ...
(Date:12/19/2014)... warns parents that buying an older car for their teens may ... drivers killed in the United States between 2008 and 2012 were ... lacked important safety features that are available on newer cars, the ... were in cars at least six years old, 34 percent were ... cars 11 to 15 years old, and 17 percent were in ...
Breaking Medicine News(10 mins):Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2Health News:Attractive Evening Dresses Announced by Discount-Dress.com 2Health News:Older Cars a Bad Choice for Younger Drivers 2
... The Food Allergy &,Anaphylaxis Network (FAAN) will hold ... May 31, 2008. Many families struggle with,how best to ... living with food allergies for years or are dealing ... attendees will learn tips and strategies for living better,while ...
... potent cancer gene. , The gene, known as ERG, ... including leukemia and sarcoma. American scientists showed in 2005 that ... cancers. , It was unclear, however, what function ERG ... so carcinogenic when mutated. , The team at WEHI ...
... Assisted living communities save time and money accepting ... electronic payments direct from resident bank accounts, ... today that it,has added PaySimple, the leading provider ... its customers to help simplify resident billing,and collection ...
... 27 Health Fitness,Corporation (OTC Bulletin Board: HFIT), ... management solutions, today announced that,it has completed its ... plan, the company repurchased 1.14 million shares of ... with Securities and Exchange,Commission Rule 10b-18 and other ...
... to be poorer and without insurance , , TUESDAY, May 27 ... receive treatment, even though they have access to care, according ... funding from drug maker GlaxoSmithKline, was published in the May ... . , The research involved 97 Boston-area men with the ...
... The current recommended daily allowance (RDA) of vitamin D ... research reveals that children may need and can safely ... report in The Endocrine Societys Journal of Clinical Endocrinology ... bone health of children worldwide and may have other ...
Cached Medicine News:Health News:FAAN Brings 'Food Allergies: Living and Learning' to Annual Food Allergy Conference in New York 2Health News:FAAN Brings 'Food Allergies: Living and Learning' to Annual Food Allergy Conference in New York 3Health News:Vigilan Offers PaySimple to Simplify Resident Billing and Collection 2Health News:Health Fitness Completes Share Repurchase Plan 2Health News:Men With Low Testosterone Not Receiving Treatment 2Health News:Current vitamin D recommendations fraction of safe, perhaps essential levels for children 2
(Date:12/19/2014)... NEW YORK , Dec. 18, 2014 ... meals, addressing hearing health was forgotten. But Audicus ... resolve to hear better this new year. ... condition facing the aging population, though it is often ... one in four has a hearing aid, mainly due ...
(Date:12/19/2014)... INC. (NYSE: RMD ) today announced that it ... on Thursday, January 22, 2015, after the New York Stock ... be issued after 1:00 p.m. US Pacific Time and the ... future outlook. The earnings call is scheduled to ... webcast of the call can be accessed on ResMed,s Investor ...
(Date:12/19/2014)... witnessed robust development with the growth pace keeping at 20%-30% ... 2012, the size of China separating ... soaring to 16.3%. It is projected that China ... by around 20% in the upcoming years and that the ... An integrated membrane industrial system has taken shape in ...
Breaking Medicine Technology:Audicus Will Help People Resolve to Hear Better in 2015 2ResMed To Announce Second Quarter 2015 Results 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
... , SALT ... City based software company, announces the launch of a new online vision ... with existing in-office therapy methods. , eyeQ was introduced at ... Brad Habermehl believes the eyeQ program adds significant value to ...
... , MISSISSAUGA, Ontario, Nov. 24 ... technology and products targeting the immunoassay segment of the IVD ... progressing to the next phase of the commercialization of CardioGenics, ... the agreement with Merck Chimie that was executed earlier this ...
Cached Medicine Technology:Infinite Mind Announces the Launch of a New Online Vision Therapy Program eyeQ 2CardioGenics Provides Update on Agreement with Merck Chimie for Its Silver Coated Paramagnetic Beads 2CardioGenics Provides Update on Agreement with Merck Chimie for Its Silver Coated Paramagnetic Beads 3
... path that allows users to take full ... potential to combine two units offers fully ... stimulating coil. The ability to change pulse ... level of each Magstim 200 allows for ...
... is a surgical approach to glaucoma management ... application. The ciliary body (which produces aqueous ... the anterior or posterior segment, through the ... are easily and accurately identified utilizing endoscopy. ...
... surgical approach to glaucoma management that employs ... ciliary body (which produces aqueous humour) is ... or posterior segment, through the endoscope in ... and accurately identified utilizing endoscopy. This allows ...
... of German Craftsmanship have produced ... the world. Ocutek® now makes ... holders of the coveted Meisterbrief ... apprenticeship, are qualified to become ...
Medicine Products: