Navigation Links
Breast Cancer Radiation Before 1984 Tied to Heart Disease
Date:1/17/2011

MONDAY, Jan. 17 (HealthDay News) -- Among long-term breast cancer survivors, those who were treated with radiotherapy before 1984 appear to face much higher rates of death due to heart disease, new French-Swiss research indicates.

The study results, published in the Jan. 25 issue of the Journal of the American College of Cardiology, "confirm that radiotherapy for breast cancer, such as that practiced until the mid-1980s, increased the long-term risk of death from cardiac disease," the authors said in a journal news release.

In the study, the researchers tracked nearly 4,500 women who had been treated for breast cancer between 1954 and 1984 at the Institut Gustave Roussy (IGR) in Villejuif, France.

All of the women in the study had survived their initial breast cancer diagnosis for a minimum of five years, and the study tracked such survivors for an average of 28 years, making it one of the few investigations to explore the long-term side effects of breast cancer treatment.

The analysis, based on data from medical records and national registries, found that about two-thirds of the women had been treated with radiation during the study time-frame, according to study author Florent de Vathaire of the Radiation Epidemiology Group at INSERM and the IGR, and colleagues.

The cause of death could be determined for the vast majority of the 2,637 breast cancer survivors who ultimately died before the age of 95. The investigators found that 421 died from cardiovascular disease, including 236 from cardiac diseases and 185 from vascular diseases.

The team further established that the risk of dying from heart disease was 1.76 times higher among those exposed to radiation therapy compared with those who were not exposed. In addition, the risk of dying from cardiovascular diseases as a whole was 1.56 greater among this group.

Not all types of exposure to radiation therapy appeared to have the same negative consequences for heart health. Women whose tumor was on the left side (and were therefore exposed to radiotherapy on the left side) faced a higher risk for cardiac disease than those whose tumor was located on the right side, they found.

In an editorial accompanying the study, Dr. Ronald M. Witteles, of the division of cardiovascular medicine at the Stanford University School of Medicine, described the new analysis as both "convincing" and "important." He also cautioned that despite technological advances, radiation dosages used today among breast cancer patients "remain substantial." Physicians, he noted, should stay vigilant with respect to the potential harm such exposure can cause.

More information

For more on breast cancer and radiation therapy, visit BreastCancer.org.

-- Alan Mozes

SOURCE: Journal of the American College of Cardiology, news release, Jan. 17, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Finds Racial Disparity in Breast Cancer Outcomes
2. Study provides molecular rationale for combining targeted agents to treat breast cancer
3. Preoperative breast MRI suggests high cancer yield
4. Quality of life measures in breast cancer clinical trials
5. Quality of Life Key Measure in Breast Cancer Clinical Trials
6. Teens Breast-fed as Infants Have Stronger Leg Muscles
7. Breast Cancer Outcome: Your Doctor Matters
8. High dietary fat, cholesterol linked to increased risk of breast cancer
9. Experimental Drug Helps Fight Aggressive Breast Cancer: Report
10. More Evidence Links Avastin to Heart Failure in Breast Cancer Patients
11. Peptide delivers 1-2 punch to breast cancer in pre-clinical study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer Radiation Before 1984 Tied to Heart Disease
(Date:5/26/2016)... Knoxville, TN (PRWEB) , ... May 26, 2016 ... ... professional fitness education and products recently hosted the first PowerWave Instructor Certification Course ... Fouts, who lead a group of fitness professional through the 8 hour interactive ...
(Date:5/26/2016)... ... May 26, 2016 , ... OncLive® , a ... Cancer Institute-designated University of Virginia (UVA) Cancer Center to its quickly ... and marketing teams will publicize and promote public awareness of UVA Cancer Center’s ...
(Date:5/26/2016)... Redwood City, CA (PRWEB) , ... May 26, 2016 , ... ... time, Silicon Valley-based startup, The Dough Bar, has ignited an undeniable buzz ... shake -- a doughnut. But not just any doughnut.  These doughnuts are packed with ...
(Date:5/26/2016)... ... May 26, 2016 , ... Workrite ... sales leadership and to further develop their rapidly expanding portfolio of customer and ... with a concentration in Marketing and an M.B.A. with concentration in management from ...
(Date:5/26/2016)... ... May 26, 2016 , ... Saint Francis ... several years, and the efforts have paid off. Since implementation of these ... of care to enhance perioperative patient experiences and reduce costly complications. Since implementation ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 Open Access Journal ... Neurophysiology  Elsevier , a world-leading provider ... today announced the launch of Clinical Neurophysiology ... that focuses on clinical practice issues in clinical neurophysiology. ... series, normal values and didactic reviews. It is an ...
(Date:5/24/2016)... 2016 Een app die artsen ... collectief patiënten kunnen behandelen, hun kennis kunnen delen en ... de nieuwe en revolutionaire MDLinking App, ontwikkeld door een ... dr. Hans Flu en oncologisch chirurg dr. Gijs ... is, wordt op dinsdag 24 mei officieel gepresenteerd op ...
(Date:5/23/2016)... , May 23, 2016 Global ... 163 pages, profiles 12 companies and the Paclitaxel analysis ... figures on the industry and its players. ... comprehensive in nature, details the current state of the ... including definitions, classifications, applications and industry chain structure. The ...
Breaking Medicine Technology: