Navigation Links
Breast Cancer Gene Tied to Diagnosis at Younger Age
Date:10/16/2009

Researchers concerned that disease may be developing earlier

FRIDAY, Oct. 16 (HealthDay News) -- Women with a high genetic risk of developing breast cancer are being diagnosed sooner than similar women in the past, which may suggest that tumors are developing earlier in the younger generation, researchers say.

The finding, presented at the 2009 Breast Cancer Symposium, held last week in San Francisco, could potentially affect how women are screened for breast cancer.

About 5 percent to 10 percent of breast cancer cases are thought to be connected to a genetic mutation that's also linked to ovarian cancer. Women with the mutations, known as BRCA1 or BRCA2, have an increased risk of developing breast tumors. Over a lifetime, 60 percent of them will develop the disease, according to the American Cancer Society. By comparison, 12 percent of women in the general population will develop breast cancer.

Women who have the genetic mutation -- or whose mothers or aunts have it -- are advised to be screened for breast cancer starting when they are 25. Mammography and MRI are now recommended for these women.

In the new study, the researchers examined the medical records of 132 women with the genetic mutation who took part in the University of Texas M.D. Anderson Cancer Center's clinical cancer genetics program between 2003 and 2009. Of those, 107 had a mother or aunt with breast or ovarian cancer.

The median age of diagnosis in the newer generation was 42, but 47 in the older women. The study authors report that this is worrisome because it could mean that the cancer is developing earlier.

"These findings are certainly concerning and could have implications on the screening and genetic counseling of these women," said study co-author Dr. Jennifer Litton, an assistant professor at M.D. Anderson Cancer Center, in a news release from the center. "In BRCA-positive women with breast cancer, we actually might be seeing true anticipation -- the phenotype or cancer coming out earlier per generation. This suggests more than the mutation could be involved, perhaps lifestyle and environmental factors are also coming into play."

More information

Learn more about the BRCA genetic mutation from the U.S. National Cancer Institute.



-- Randy Dotinga



SOURCE: University of Texas M.D. Anderson Cancer Center, news release, Oct. 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Photos: Avon Foundation for Women Celebrates Breast Cancer Awareness Month
2. Mars Lends Sweet Support in Fight Against Breast Cancer Through Its M&Ms(R) And Dove(R) Chocolate Brands, as Well as Its Celebrated Race Team
3. Atomic Tattoos Announces "Tats for Tatas" October Fundraising Event to Benefit Local Breast Cancer Research
4. Bedazzled Bras Benefit Breastcancer.org
5. Saudi Arabia Expands Breast Cancer Awareness Programs
6. Video: Cities and States Around the U.S. Recognize October 13 as Metastatic Breast Cancer Awareness Day
7. Longaberger Offers NFL Breast Cancer Awareness Basket Set as Part of Crucial Catch Campaign
8. Mastectomy Not First Choice for Most Breast Cancer Patients
9. Cash for Gold USA Continues to Fight Against Breast Cancer During National Breast Cancer Month
10. Renowned Southern California Doctors Emphasizing Early Detection During Breast Cancer Awareness Month
11. With Hormone Therapy, Tender Breasts May Signal Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... DIEGO, California (PRWEB) , ... June 20, 2017 ... ... product documentation and help content solutions for the enterprise, is proud to announce ... properties, including CRM, e-commerce, ticketing systems, company websites, and more to provide a ...
(Date:6/20/2017)... Cincinnati, Ohio (PRWEB) , ... June 20, 2017 ... ... with gum disease in Cincinnati, OH for leading-edge care, whether or ... advances in laser dentistry. Using the BIOLASE WaterLase® iPlus™ laser, she targets bacteria ...
(Date:6/20/2017)... ... June 20, 2017 , ... With certifications and experience ... in Denville, NJ, Drs. Adam and Hal Kimowitz are currently accepting new patients at ... traditional orthodontics can cause for some patients, which is why they offer the latest ...
(Date:6/20/2017)... ... June 20, 2017 , ... This year, participants ... focused on finding product improvements that could reduce the occurrence of unplanned extubations ... need help breathing or to provide medication. Sometimes, patient movement can cause unplanned ...
(Date:6/20/2017)... , ... June 20, 2017 , ... ... makers of SweetLeaf® Stevia Sweetener, Michael P. May, Ph.D., recently accepted the distinguished ... Export Recognition Program selected Wisdom Natural Brands (WNB), and 16 other businesses from ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... June 12, 2017 Kineta, Inc., a biotechnology company ... Kineta Vice President of R&D and Head of Virology ... Pandemic Preparedness for the Northwest and Beyond meeting sponsored ... June 14, 2017 from 8:30-10:30 AM PDT at the Agora ... Dr. Bedard will be joined by other leaders ...
(Date:6/8/2017)... Fla. , June 8, 2017  Less than ... that hit more than 200,000 companies, including hospital networks, ... being heralded as one of the largest online extortion ... in the healthcare market, it is imperative that providers ... protect their data from this — and many other ...
(Date:6/7/2017)... June 6, 2017  Diplomat Specialty Infusion Group, a brand of ... to its Iowa location. The ... now features an ISO 7 cleanroom—the standard needed to compound ... a low level of pollutants. ... consumers and better serve our Iowa patients," ...
Breaking Medicine Technology: