Navigation Links
Breast Cancer Gene Tests Won't Help Most Women: Report
Date:4/1/2013

MONDAY, April 1 (HealthDay News) -- The benefits of genetic testing to assess the risk of breast and ovarian cancers linked to the BRCA gene are limited to a small number of women, a new report indicates.

Mutations in the BRCA1 and BRCA2 genes greatly increase a woman's risk of developing these cancers. Women with these mutations have a 70 percent chance of developing breast cancer -- which is five times greater than in the general population -- and increase their lifetime risk of ovarian cancer from less than 2 percent to as high as 46 percent.

An important step in preventing these cancers is helping women understand their risk, according to the U.S. Preventive Services Task Force.

In preparing a draft report and recommendations, the task force examined available evidence to determine if genetic counseling and testing could benefit women most likely to have BRCA mutations.

The task force concluded that more than 90 percent of American women -- those whose family history does not indicate an increased risk for BRCA1 or BRCA2 mutations -- will not benefit from genetic testing or counseling.

This is because current tests often provide inconclusive results and these women could be burdened with the uncertainty of whether they are at increased risk for cancer. Many of these women might choose to take powerful medications or have major surgery to reduce their risk of cancer, which would be unnecessary if they were not at increased risk.

Therefore, the task force said it continues to recommend against genetic counseling and BRCA testing in these women.

"At this point, scientific evidence only shows that BRCA1 and BRCA2 testing is beneficial for women who have reviewed their family history of breast or ovarian cancer with a primary-care professional and discussed the pros and cons of the screening test with a trained genetic counselor," task force chairwoman Dr. Virginia Moyer said in task force news release.

"We hope that further research into ways to use genomic science, such as identifying women who have harmful BRCA genes but do not have a family history of cancer, could improve screening practices and even prevent some cancers," she added.

The task force said it also found evidence to recommend that primary-care health providers screen women who have family members with breast or ovarian cancer to determine if their family history is associated with an increased possibility of having BRCA1 or BRCA2 mutations.

In situations where this is the case, women should receive in-depth genetic counseling to thoroughly review family history and -- if indicated and after weighing the pros and cons of BRCA testing -- undergo the test, the report said.

The recommendations apply to women who have not been diagnosed with breast or ovarian cancer but who have family members with breast or ovarian cancer and whose BRCA status is unknown.

The draft report and recommendations will be open for public comment until April 29.

"Every year, too many American women and families are faced with the challenge of dealing with breast and ovarian cancer diagnosis and treatment," Moyer said. "We need better treatments, better screening methods and, most importantly, better ways to prevent cancer."

More information

The U.S. National Cancer Institute has more about BRCA mutations and cancer risk.

-- Robert Preidt

SOURCE: U.S. Preventive Services Task Force, news release, April 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Eliminating the good cholesterol receptor may fight breast cancer
2. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
3. Researchers develop a new cell and animal model of inflammatory breast cancer
4. Scientists uncover multiple faces of deadly breast cancer
5. Depo-Provera Birth Control Might Raise Breast Cancer Risk
6. Routine mammograms may result in significant overdiagnosis of invasive breast cancer
7. Mayo Clinic launches whole genome breast cancer study
8. Breast cancer patients suffer treatment-related side effects long after completing care
9. Teen Drinking May Boost Odds of Precancerous Breast Changes
10. Stress contributes to cognitive declines in women with breast cancer, researcher says
11. Breast Cancer Treatment Side Effects May Last for Years
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer Gene Tests Won't Help Most Women: Report
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. ... of best seller "LOVE, MEDICINE and MIRACLES") addresses touchy topics related to Death ... podcasted thereafter . Dr. Bernie Siegel, author of a plethora of essential ...
(Date:4/29/2016)... Southlake, Texas (PRWEB) , ... April 29, 2016 , ... ... and neck pain, is proud to announce one of their physicians has been invited ... Osteopathic Family Physicians (Texas ACOFP) Family Practice Review conference on April 30, 2016. ...
(Date:4/29/2016)... ... ... Melanoma is the deadliest type of skin cancer. Although only about 1 percent of skin ... More than 10,000 people are expected to die of melanoma this year. The risk increases ... of the most commonly diagnosed cancers in young women. A recent breakthrough in genetic studies ...
(Date:4/29/2016)... ... April 29, 2016 , ... Jvion, ... round of funding led by Eastside Partners, with participation from existing investor Martin ... customer base and accelerate its technology and product roadmap. , “Jvion ...
(Date:4/29/2016)... ... ... Nike Softball Camp at the College of Brockport in New York is ... 10-18. All facets of the game will be covered; hitting, fielding, base-running, and team ... the finest softball facilities in the region. The outstanding professional college staff complement and ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... , le 27 Avril 2016 ... a progressé de +5% sur le trimestre, soutenu ... de consommables  Croissance de +16% des ... Mauna Kea Technologies (Euronext : MKEA, FR0010609263 ; ... confocale laser, annonce aujourd,hui son chiffre d,affaires pour ...
(Date:4/27/2016)... April 27, 2016 Elekta today ... platform will be the focal point of seven scientific ... European Society for Radiotherapy & Oncology, taking place April ... a state-of-the-art radiotherapy system and a high-field MRI scanner ... see the patient,s anatomy in real time. The MR-linac ...
(Date:4/27/2016)... , April 27, 2016   Zillion ... digital health technology platform, which specializes in live ... into scalable digital products, Zillion enables companies to ... empower consumers to take control of their health. ... video conferencing – including one-to-one, group and webcast ...
Breaking Medicine Technology: