Navigation Links
Breast Cancer Drug May Harm the Heart More Than Thought
Date:8/31/2012

By Kathleen Doheny
HealthDay Reporter

THURSDAY, Aug. 30 (HealthDay News) -- Women with breast cancer who are treated with the cancer drug Herceptin may have more long-term cardiac problems than experts have thought, new research suggests.

It has been known that women treated with anti-cancer drugs known as anthracyclines and Herceptin (trastuzumab) are at higher risk for heart failure and cardiomyopathy, a weakening of the heart muscle.

But, that information on risks has come primarily from clinical trials, which typically exclude women aged 70 and older and those with co-existing chronic diseases, so it doesn't necessarily give a real-world picture, the researchers noted.

"The risk of heart failure associated with these drugs might be higher than what has been shown in clinical trials," explained study author Erin Aiello Bowles, an epidemiologist at Group Health Research Institute, in Seattle. Her report is published online Aug. 30 in the Journal of the National Cancer Institute.

Bowles and her colleagues evaluated 12,500 women diagnosed with invasive breast cancer from 1999 through 2007 in eight different health systems. The patients' average age was 60. The follow-up time ranged from more than two years to nearly seven.

The researchers used data from medical records and other sources to track type of cancer treatment and diagnoses of cardiac problems.

The risk of heart failure was 1.4 times higher in those treated only with an anthracycline at the five-year mark. That was about the same increase as those treated with other types of cancer drugs. However, those on Herceptin alone had more than four times the risk of heart problems compared to those who did not take the medication, the study stated.

And, the biggest increase in risk was seen in those on both anthracyclines and Herceptin. Those patients showed a sevenfold increased risk at the five-year mark, the researchers said.<
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. More heart problems with 2 chemo drugs for breast cancer
2. Possible therapy for tamoxifen resistant breast cancer identified
3. Exploring exercise benefits for breast cancer patients
4. Breast Cancer Drug Might Help Men on Prostate Cancer Therapy
5. Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer
6. Excess Pounds Raise Risk of Breast Cancer Recurrence, Death: Study
7. Johns Hopkins team finds ICU misdiagnoses may account for as many annual deaths as breast cancer
8. Lack of sleep found to be a new risk factor for aggressive breast cancers
9. Obese and overweight women face increased risk of recurrence of most common type of breast cancer
10. RI Hospital researcher: Older women may not benefit from radiotherapy after breast surgery
11. New survey: Women want to SEE breast reconstruction results before cancer surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer Drug May Harm the Heart More Than Thought
(Date:5/23/2013)... 2013 Vegas Hotel Escapes, the ... announce all new vacation packages for the upcoming ... Las Vegas for this patriotic holiday will be ... to VegasHotelEscapes.com's new special pricing available on VegasHotelEscapes.com's ... it guarantees the lowest prices possible on vacation ...
(Date:5/23/2013)... New Jersey (PRWEB) May 23, 2013 ... Americans suffering from irritable bowel syndrome (IBS), the food ... on your holiday fun. , “While hot dogs and ... plate during the warm weather months, IBS sufferers often ... says Deborah Sokol, MD, a gastroenterologist with Lourdes Medical ...
(Date:5/23/2013)... 23, 2013 Onlinefitnessreview.com recently published a ... to determine what makes this diet work and how ... highlights three main components of the program: eliminating foods ... mindset and the personal motivation that is needed to ... days to keep the metabolism rate in top gear. ...
(Date:5/23/2013)... Mann HealthDay Reporter , , THURSDAY, May 23 ... take to help treat hip and knee osteoarthritis may ... for developing glaucoma, a small new study of older ... an increase of intraocular pressure (IOP) or pressure inside ... leading causes of blindness. In the ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Memorial Day ... , Chaplains have been a part of the U.S. ... Day, like those preceding it, these men and women ... the United States of America. As veterans transition ... their migration to the workplace chaplaincy world. , ...
Breaking Medicine News(10 mins):Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 2Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 3Health News:Onlinefitnessreview.com Publishes 7 Day Belly Blast Diet Review 2Health News:Glucosamine Supplements Tied to Risk of Eye Condition 2Health News:Glucosamine Supplements Tied to Risk of Eye Condition 3Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 3
... affect psychological well-being, , FRIDAY, Sept. 25 (HealthDay News) -- ... lose IQ points. , The good news is that it ... at least one expert believes that part of the reason ... in the United States and elsewhere. , That,s the view ...
... Life ... with one of its Northwest Division President,s Awards on Monday, Sept. 21. , ... Kirkland, WA (PRWEB) September 25, 2009 -- ... Care Center of Kirkland , with one of its Northwest Division President,s Awards on Monday, ...
... ... portable oxygen machine from Invacare with an amazing 1.8 liters per minute ... oxygen output. Now, oxygen therapy patients requiring large doses of oxygen can ... mobility and freedom. This new portable concentrator is now available for online ...
... researchers say , THURSDAY, Sept. 24 (HealthDay News) -- ... with carpal tunnel syndrome who don,t have severe nerve ... included 44 patients who had surgery and 52 patients ... ultrasound. A year after treatment, the patients, hand function ...
... CA SEPTEMER 24, 2009 Results from a ... combination of giving patients clopidogrel, a blood thinner commonly ... such as omeprazole, known as proton pump inhibitors (PPIs), ... studies had suggested. The results were presented at the ...
... BEDFORD, Mass., Sept. 24 ... HOLX ), a leading developer, manufacturer and supplier ... dedicated to serving the healthcare needs of women, today ... Clinical Excellence (NICE), in its updated guidance for hysteroscopic ...
Cached Medicine News:Health News:Spanking May Lower Kids' IQs 2Health News:Spanking May Lower Kids' IQs 3Health News:Local Nursing Home Leader Receives Life Care's Northwest Division President's Award 2Health News:New Invacare SOLO2 Portable Oxygen Concentrator Available At Vitality Medical 2Health News:New Invacare SOLO2 Portable Oxygen Concentrator Available At Vitality Medical 3Health News:New Invacare SOLO2 Portable Oxygen Concentrator Available At Vitality Medical 4Health News:New Invacare SOLO2 Portable Oxygen Concentrator Available At Vitality Medical 5Health News:Surgery Best for Carpal Tunnel Syndrome 2Health News:Surgery Best for Carpal Tunnel Syndrome 3Health News:Cogent trial shows lack of adverse interaction between clopidogrel and stomach medicine 2Health News:New U.K. NICE Guidance Supports Use of Hologic's Adiana(R) Permanent Contraception System 2Health News:New U.K. NICE Guidance Supports Use of Hologic's Adiana(R) Permanent Contraception System 3Health News:New U.K. NICE Guidance Supports Use of Hologic's Adiana(R) Permanent Contraception System 4
(Date:5/23/2013)... 2013  Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ... 2013 Life Science Firm of the Year by the Tech ... honored at the TCM,s 25 th Annual Tech Awards ... Tech Awards Celebration recognizes the leaders and innovators in the ... and the surrounding regions. "We are ...
(Date:5/23/2013)... y PARÍS, 24 de mayo de 2013 /PRNewswire/ ... destacado desarrollador y fabricante de herramientas de precisión ... y tratamiento de la enfermedad vascular periférica y ... ADVISE ( Ad enosine V asodilator ... II durante la sesión de ensayo clínico hot ...
(Date:5/23/2013)... , May 23, 2013 Neurocrine Biosciences, Inc. (Nasdaq: ... Gorman , President and Chief Executive Officer of Neurocrine ... Annual dbAccess Health Care Conference in Boston.   ... at 11:20 a.m. Eastern Time / 8:20 a.m. Pacific Time.  ... the Company,s website at http://www.neurocrine.com . ...
Breaking Medicine Technology:Vanda Pharmaceuticals Named the 2013 Life Science Firm of the Year by the Tech Council of Maryland 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6
... 2 "A two-year,survival rate of more ... anaplastic,astrocytoma suggests a breakthrough in this devastating ... Neuro-Oncologist and Coordinating,Investigator of the Phase IIb ... or refractory high-grade glioma, while presenting the,data ...
... American Transplant Congress in Toronto, MIAMI, June ... in,the Departments of Surgery and Pathology at the ... have corroborated the value of,monitoring cell- mediated immunity ... a regular laboratory assay of cell function,(ImmuKnow(R)/Cylex). Their ...
Cached Medicine Technology:Clinical Proof of Concept for TGF-beta 2-Inhibitor AP 12009 in Phase Iib EMEA provides Guidance on Phase III Design and Approval Requirements 2Clinical Proof of Concept for TGF-beta 2-Inhibitor AP 12009 in Phase Iib EMEA provides Guidance on Phase III Design and Approval Requirements 3Clinical Proof of Concept for TGF-beta 2-Inhibitor AP 12009 in Phase Iib EMEA provides Guidance on Phase III Design and Approval Requirements 4University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients 2University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients 3University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients 4
Near point card 4 1/2 to 24 PT 5 1/2" x 8"....
... sided contemporary reading card was designed by ... range of near point exercises including words, ... 20/400, 20/260, 20/200, 20/100, 20/65, 20/50, 20/40, ... decimal reading in English and metric, Jaeger, ...
Standard reading test. Music Bars and Tables...
... is an economically priced 4-channel data ... research use in the fields of ... biology, zoology, biochemistry and biomedical engineering. ... signal conditioners and transducers. Two Pod ...
Medicine Products: