Navigation Links
Breast Cancer Drug May Harm the Heart More Than Thought
Date:8/31/2012

By Kathleen Doheny
HealthDay Reporter

THURSDAY, Aug. 30 (HealthDay News) -- Women with breast cancer who are treated with the cancer drug Herceptin may have more long-term cardiac problems than experts have thought, new research suggests.

It has been known that women treated with anti-cancer drugs known as anthracyclines and Herceptin (trastuzumab) are at higher risk for heart failure and cardiomyopathy, a weakening of the heart muscle.

But, that information on risks has come primarily from clinical trials, which typically exclude women aged 70 and older and those with co-existing chronic diseases, so it doesn't necessarily give a real-world picture, the researchers noted.

"The risk of heart failure associated with these drugs might be higher than what has been shown in clinical trials," explained study author Erin Aiello Bowles, an epidemiologist at Group Health Research Institute, in Seattle. Her report is published online Aug. 30 in the Journal of the National Cancer Institute.

Bowles and her colleagues evaluated 12,500 women diagnosed with invasive breast cancer from 1999 through 2007 in eight different health systems. The patients' average age was 60. The follow-up time ranged from more than two years to nearly seven.

The researchers used data from medical records and other sources to track type of cancer treatment and diagnoses of cardiac problems.

The risk of heart failure was 1.4 times higher in those treated only with an anthracycline at the five-year mark. That was about the same increase as those treated with other types of cancer drugs. However, those on Herceptin alone had more than four times the risk of heart problems compared to those who did not take the medication, the study stated.

And, the biggest increase in risk was seen in those on both anthracyclines and Herceptin. Those patients showed a sevenfold increased risk at the five-year mark, the researchers said.<
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. More heart problems with 2 chemo drugs for breast cancer
2. Possible therapy for tamoxifen resistant breast cancer identified
3. Exploring exercise benefits for breast cancer patients
4. Breast Cancer Drug Might Help Men on Prostate Cancer Therapy
5. Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer
6. Excess Pounds Raise Risk of Breast Cancer Recurrence, Death: Study
7. Johns Hopkins team finds ICU misdiagnoses may account for as many annual deaths as breast cancer
8. Lack of sleep found to be a new risk factor for aggressive breast cancers
9. Obese and overweight women face increased risk of recurrence of most common type of breast cancer
10. RI Hospital researcher: Older women may not benefit from radiotherapy after breast surgery
11. New survey: Women want to SEE breast reconstruction results before cancer surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breast Cancer Drug May Harm the Heart More Than Thought
(Date:8/31/2015)... ... August 31, 2015 , ... With the FCPX LUT Soft pack from Pixel Film ... a Lookup Table that contains a mathematical formula for modifying an image. The LUT changes ... 60 soft CUBE LUT files. , FCPX LUT Soft requires Final Cut Pro X ...
(Date:8/31/2015)... ... 31, 2015 , ... How can healthcare meet the challenge ... , In a commentary for The American Journal of Managed Care , ... efficacy,” which would bind parties together in agreements to intervene at the earliest ...
(Date:8/31/2015)... CA (PRWEB) , ... August 31, 2015 , ... ... print and digital marketing communications company announced today that it has officially launched ... DP President, the new website and brand refresh are more closely aligned with ...
(Date:8/31/2015)... ... , ... The dental implant and prosthetic market in the U.S. is projected ... Press Room ) More than 30 million Americans are missing all their teeth ... for dental implants, the National Association of Dental Laboratories (NADL) created the “What’s In ...
(Date:8/31/2015)... , ... August 31, 2015 , ... ... franchise business with a ribbon-cutting ceremony on Aug. 26, generously hosted by the ... booking inspection appointments via AdvantaClean’s National Call Center and website since Aug. 17. ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios, FCPX Plugin Developer, Releases FCPX LUT Soft 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 3Health News:Diablo Publications Launches New Company Website 2Health News:Diablo Publications Launches New Company Website 3Health News:Dental Association Raises Awareness as Implant Industry Grows 2Health News:Dental Association Raises Awareness as Implant Industry Grows 3Health News:Dental Association Raises Awareness as Implant Industry Grows 4Health News:Ribbon Cutting Launches AdvantaClean of Madison County 2
... been stepped up in China, the official Xinhua news agency ... much dreaded Avian influenza or “bird flu” caused by H5N1 ... ago. China has accelerated efforts to monitor bird flu status ... at large and officials have been urged to keep an ...
... evidence supporting the view that ancient men did perform brain ... claim to have unearthed a skull which appears to date ... The skull was found during excavations that were being carried ... ,Georgi Nehrizov informed the press that the skull, which they ...
... the total spending on Medicaid has shown its slowest pace ... a better economy// that has held down new enrollments, cost-containment ... according to a new survey. ,Medicaid is the state-federal health ... of 2.8 percent in fiscal 2006, according to the survey ...
... authority in organ transplantation and an eminent personality delivered ... (CMCH) Ludhiana recently. ,Speaking at the gathering he ... information about organ donation in India and how exactly ... organs after death. ,He observed that for ...
... States will be oganised by the Union Health and Family ... agenda is to come out with a plan to combat ... in India. Chikungunya has taken several lives, predominantly in Kerala. ... of the Health Ministers of the four southern States, Gujarat, ...
... by her ovaries according to a new report.The study conducted ... women put more time and effort into their appearance when ... and makeup affected at that time of the month a ... other alter as well. ,Study's lead author, UCLA ...
Cached Medicine News:Health News:Lowest Spending growth in US Medicaid 2Health News:Crying Need for Awareness on Organ Donation in India: Sir Peter Morris 2Health News:Women’s Fashion Sense Linked to Her Ovulatio 2
(Date:8/31/2015)... LAKE, N.J. and STAMFORD, Conn. ... U.S. pharmaceutical subsidiary of Eisai Co., Ltd., and Purdue ... a worldwide collaboration agreement for the development and commercialization ... dual orexin receptor antagonist entering Phase III clinical development ... the terms of the agreement, Eisai and Purdue Pharma ...
(Date:8/31/2015)... , Aug. 31, 2015 Bionomics Limited (ASX:BNO, ... development of innovative therapeutics for the treatment of diseases ... announced that its BNC101 IND submission has passed review ... plans to initiate a Phase 1 clinical trial in ... metastatic pancreatic cancer prior to 31 December 2015. ...
(Date:8/31/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/wmn42n/prescription_pain ) has ... Drugs - Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ ... Opportunities: 2015 - 2020 Analysis and Forecasts" ... is defined as an unpleasant sensory and emotional ... At some point, everyone experiences pain. Pain may ...
Breaking Medicine Technology:Eisai and Purdue Pharma Enter Worldwide Collaboration to Develop and Commercialize Lemborexant 2Eisai and Purdue Pharma Enter Worldwide Collaboration to Develop and Commercialize Lemborexant 3Eisai and Purdue Pharma Enter Worldwide Collaboration to Develop and Commercialize Lemborexant 4Eisai and Purdue Pharma Enter Worldwide Collaboration to Develop and Commercialize Lemborexant 5Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 2Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 3Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 4Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 2Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 3
... announced that the U.S. Food and Drug Administration ... treatment of adult patients with glioblastoma multiforme (GBM) ...  The portable, wearable device delivers an anti-mitotic, anti-cancer ... The NovoTTF is a novel, first-in-class treatment option ...
... 2011 StelKast is proud to announce the ... Acetabular Liners. EXp™, a blend of antioxidant and ... consulting support of Steven Kurtz, Ph.D. and Exponent, ... clearance for large diameter cobalt-chrome femoral heads and ...
Cached Medicine Technology:FDA Approves the NovoTTF-100A System for the Treatment of Patients With Recurrent Glioblastoma Multiforme (GBM) Brain Tumors 2FDA Approves the NovoTTF-100A System for the Treatment of Patients With Recurrent Glioblastoma Multiforme (GBM) Brain Tumors 3FDA Approves the NovoTTF-100A System for the Treatment of Patients With Recurrent Glioblastoma Multiforme (GBM) Brain Tumors 4A Better Acetabular Solution from StelKast ... Naturally 2
9mm Curved Blades with Sharp Pointed Tips; overall length 90mm; Stainless Steel....
Straight shaft with fine pointed 0.3mm Tips for Grasping Delicate Capsule; In Titanium....
Smooth colibri tip; In Titanium....
45 Degree Angle With 0.3, 12 Teeth with 5mm Tying Platform; In Titanium....
Medicine Products: