Navigation Links
Breakthrough study sheds new light on best medication for children with seizures
Date:6/11/2014

DETROIT A recently published clinical study in the Journal of the American Medical Association has answered an urgent question that long puzzled ER pediatricians: Is the drug lorazepam really safer and more effective than diazepam the U.S. Food and Drug Administration-approved medication as first line therapy most often used by emergency room doctors to control major epileptic seizures in children?

The answer to that question based on a double-blind, randomized clinical trial that compared outcomes in 273 seizure patients, about half of whom were given lorazepam is a clear-cut "no," said Prashant V. Mahajan, M.D., M.P.H., M.B.A, one of the authors of the study.

"The results of our clinical trial were very convincing, and they showed clearly that the two medications are just about equally effective and equally safe when it comes to treating status epilepticus [major epileptic brain seizures in children]," Dr. Mahajan said. "This is an important step forward for all of us who frequently treat kids in the ER for [epilepsy-related] seizures, since it answers the question about the best medication to use in ending the convulsions and getting these patients back to normal brain functioning."

Describing the brain convulsions that were targeted by the study, its authors pointed out that status epilepticus occurs when an epilepsy-related seizure lasts more than 30 minutes. Such seizures which occur in more than 10,000 U.S. pediatric epilepsy patients every year can cause permanent brain damage or even death, if allowed to persist.

Published in JAMA, the study, "Lorazepam vs Diazepam for Pediatric Status Epilepticus: A Randomized Clinical Trial," was designed to test earlier assertions by many clinicians that lorazepam was more effective at controlling pediatric seizures. The study-authors wrote, "Potential advantages pro
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Breakthrough in RSV research to help infected children
2. Breakthrough: Nasal spray may soon replace the pill
3. Breakthrough Research Provides Valuable Insight On Cause Of Alzheimer’s
4. Diverticulitis Breakthrough Review Indicates If This Book Is Reliable – HealthReviewCenter
5. MD Anderson researcher Jim Allison wins Breakthrough Prize for his innovative cancer immunology rese
6. Breakthrough in treating leukemia, lymphoma with umbilical cord blood stem cells
7. Pacific Northwest Dry Eye Sufferers Gain Access to Breakthrough Treatment at Specialty Eyecare Group
8. Noted Experts to Lead Breakthrough Conversation at Center for Hispanic Leadership, December 2nd Hispanics in Healthcare Forum
9. Study reveals potential breakthrough in hearing technology
10. Children’s Cancer & Blood Foundation Breakthrough Ball Gala Honored Margo & John Catsimatidis, Amar’e Stoudemire and Dr. Patricia J. Giardina
11. Effective and Safe Cancer Vaccine? Breakthrough Alternative Cancer Treatment Available Through Special Research Program
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough study sheds new light on best medication for children with seizures
(Date:8/30/2014)... "My niece developed a nighttime fever, and I ... fever might get worse," said an inventor from Montgomery, ... how she was doing, I developed this monitoring system." ... a child's temperature. The unit instantly alerts parents if ... medical care can be given, which is designed to ...
(Date:8/30/2014)... August 2014: Transvenous lead extraction (TLE) is clinically successful ... from the European Lead Extraction ConTRolled (ELECTRa) registry presented ... by Dr Maria Grazia Bongiorni, chair of the registry,s ... cardiac implantable electronic devices (CIED) implant procedures has grown ... of complications has increased and leads are often the ...
(Date:8/30/2014)... The new review published by Daily Gossip ... Karen Brimeyer, who wanted to make her guide accessible to ... is now easy to find in the form of an ... the author of the new method shares all her tips ... writes in its review that the leaky gut syndrome can ...
(Date:8/30/2014)... Flagstaff, AZ (PRWEB) August 30, 2014 Jake ... High School while in the Back2Basics Outdoor Adventures ... want to finish high school so I can actually start ... need English and math, and I'm done.” , He has ... the initial Back2Basics program. Most clients choose to continue on ...
(Date:8/30/2014)... As 500 Zoloft lawsuits pending ligation contend the SSRI ... Wright & Schulte LLC recently learned of a remand issued ... remand in the Zoloft lawsuits was granted to 25 ... in one SSRI lawsuit filed jointly under MDL ... lawsuit sent back to the Missouri state court in which ...
Breaking Medicine News(10 mins):Health News:Transvenous lead extraction clinically successful in 98 percent of cases 2Health News:Transvenous lead extraction clinically successful in 98 percent of cases 3Health News:Leaky Gut Cure Review Reveals Unique Method to Stop Chronic Symptoms 2Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 2Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 3Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 4Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 5
... Designed to Reduce the Risk of a Subsequent Stroke, ... today,announced the launch of The TIA (Transient Ischemic Attack) ... the first of its kind in,Central Texas -- in ... stroke after TIA., A TIA is a "warning ...
... NET SatisFAXtion recognized for highly reliable and secure VoIP fax solutions ... ... (Vocus) October 27, 2008 -- FaxBack® , the leading provider ... INTERNET TELEPHONY® Magazine - the VoIP authority since 1998 - has ...
... - Special Needs Plan focuses on added benefits ... for Medicare beneficiaries with chronic health conditions -, ... the upcoming,Medicare annual enrollment period which begins November ... its 2009 Special Needs Plan,(SNP) offerings for chronically ...
... to $4.7 million in the ... revenue of $4.3 million in the first quarter of fiscal 2009, a 26% ... year-over-year increase, - Strong sales to pharmaceutical manufacturers and retail market customers ... drove growth in the first quarter - ...
... Dietitian Kris Clark, Ph.D., offers easy tips ... and fun - Halloween!, WASHINGTON, Oct. 27 If ... aged five to thirteen years, are,poised to don costumes to ... on sweet treats, registered dietitian Kris Clark,Ph.D., of Pennsylvania State ...
... Business Impact for the development of an automated process to dramatically ... , ... Irvine, CA (Vocus) October 27, 2008 -- When ... , , ,LifeMasters Supported SelfCare, Inc. is strengthening its health improvement ...
Cached Medicine News:Health News:St. David's HealthCare Launches The TIA Center for Stroke Prevention at St. David's Medical Center 2Health News:St. David's HealthCare Launches The TIA Center for Stroke Prevention at St. David's Medical Center 3Health News:FaxBack Wins the 2008 Internet Telephony Excellence Award 2Health News:FaxBack Wins the 2008 Internet Telephony Excellence Award 3Health News:Care Improvement Plus Launches 2009 Benefits in Georgia 2Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 2Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 3Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 4Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 5Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 6Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 7Health News:Sharps Compliance Corp. Reports Net Income More Than Doubles on 26% Increase in Revenue in the First Quarter of Fiscal 2009 8Health News:No Trick to Halloween Sweet Treats 2Health News:No Trick to Halloween Sweet Treats 3Health News:LifeMasters Receives 2008 Vision Award for Business Impact 2Health News:LifeMasters Receives 2008 Vision Award for Business Impact 3
(Date:8/29/2014)... and MENLO PARK, Calif. , Aug. ... (OTCQB: DMPI) ("DelMar" "the Company") today announced the ... The Company recently changed its fiscal year end to ... list its common stock on a national securities exchange ... statements as filed with the United States Securities Exchange ...
(Date:8/29/2014)... -- Research and Markets  has announced the addition ... Market 2014-2018" report to their offering. ... that connect, support, or surround bones. There are several ... cartilage, fascia, and other fibrous tissues. Repetitive use, accidents, ... result in wear and tear in these tissues. Orthopedic ...
(Date:8/29/2014)... , Aug. 29, 2014 /PRNewswire/ –  ... PHG AEX: PHIA) today announced ... Society of Cardiology (ESC) Congress 2014 ... range of its cardiology solutions serving clinicians and ... prevention and diagnosis, to treatment, ...
Breaking Medicine Technology:DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 2Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 2Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 4Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 5
... microplate washers available to handle ... cell-based assays. Embla 384 Cell ... have been optimized to avoid ... robotic compatible and have been ...
... The Labcyte miniGene LW is a new plate ... to 96 and 384 channel microplates with flat, ... equipped with 8 or 16 channel nozzle heads. ... a breeze. An optional plate stacker is available ...
Space-saving counter top model,User initiated manual defrost,Standard features (see above),Internal freezing compartment,Removable half-shelf in refrigerator,Two shelves in door,UL 471 Commercial Ref...
... to 8000 L/day of Type III Laboratory-grade ... to produce up to 8000 L/day of ... feedwater., One Complete Purification and Control Unit, ... centralized system, providing total control of all ...
Medicine Products: