Navigation Links
Breakthrough in treatment to prevent blindness
Date:12/21/2011

A UCSF study shows a popular treatment for a potentially blinding eye infection is just as effective if given every six months versus annually. This randomized study on trachoma, the leading cause of infection-caused blindness in the world, could potentially treat twice the number of patients using the same amount of medication.

"The idea is we can do more with less," said Bruce Gaynor, MD, assistant professor of ophthalmology at the Francis I. Proctor Foundation for Research in Ophthalmology. "We are trying to get as much out of the medicine as we can because of the cost and the repercussions of mass treatments."

In a paper published this month in The Lancet, researchers conducted a cluster-randomized trial, using an antibiotic called azithromycin to treat trachoma in Ethiopia, which has among the highest prevalence in the world. They picked 24 communities and randomized the two treatment options: 12 villages were given azithromycin every six months and the other 12 were treated every 12 months.

"What we found was the prevalence of trachoma is very high at baseline. Forty to 50 percent of the children in these communities have this condition," Gaynor said. "They are the most susceptible and it can quickly spread from person to person by direct or even indirect contact."

Researchers tracked both groups and found the prevalence of infection decreased dramatically.

"We found that from as high as 40 percent, the prevalence of trachoma went way down, even eliminated in some villages regardless of whether it was treated in an annual way or a biannual way," Gaynor said. "You can genuinely get same with less."

Their finding is significant because of how easily the disease spreads. Trachoma can be transmitted through touching one's eyes or nose after being in close contact with someone who is infected. It can also be spread through a towel or an article of clothing from a person who has trachoma. Even flies can transmit the disease.

Approximately 41 million people are infected with trachoma globally, and 8 million go blind because of lack of access to treatment. More than 150 million doses of azithromycin have been given out worldwide to treat this disease. Unlike other antibiotics, resistance to azithromycin has not been found in Chlamydia trachomatis, the bacteria that causes trachoma.

This and the paper's major finding give hope to Africa, Asia, the Middle East, and parts of Latin America and Australia, where trachoma is still a major problem.

"We will now be able to reach more people and make the treatment go twice as far as before," Gaynor said. "This will make a huge impact in slowing down trachoma-related blindness globally."


'/>"/>
Contact: Leland Kim
leland.kim@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Related medicine news :

1. 2011 ASH Annual Meeting to highlight latest hematology research, clinical care breakthroughs
2. Cleveland researchers find possible breakthrough to relieve pain following spinal cord injury
3. Princeton technique puts chemistry breakthroughs on the fast track
4. 2 breakthrough innovations to address maternal and newborn deaths in Sub-Saharan Africa
5. Indevr launches breakthrough colorimetric detection for microarrays using core technology from CU
6. Ben-Gurion University of the Negev researchers achieve male fertility breakthrough
7. Breakthrough in understanding the genetics of high blood pressure
8. Northern Ireland company makes major breakthrough in cancer treatment
9. An important breakthrough at the IRCM associated with osteoporosis
10. Identification and management of breakthrough cancer pain remains a challenge
11. Childrens National researchers make breakthrough in understanding white matter development
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough in treatment to prevent blindness
(Date:3/24/2017)... ... , ... “The Adventures of Joey, The Dog Who Barks at Puddles”: a ... to the fullest, as God intended. “The Adventures of Joey, The Dog Who Barks ... pursuing her passion for writing, especially about truth and human behavior. , Published by ...
(Date:3/23/2017)... ... March 23, 2017 , ... The physicians of KSF Orthopaedic Center ... Houston Area. The new location is located at 2255 E. Mossy Oaks Rd., Suite ... This newest location will provide patients living in the north Houston area (The Woodlands, ...
(Date:3/23/2017)... ... March 23, 2017 , ... PAINWeekEnd (PWE) Oklahoma City, ... Broadway Avenue, will be an educational and exciting program providing busy clinicians and ... of chronic pain. , Oklahoma is in a healthcare crisis. The state ranks ...
(Date:3/23/2017)... ... ... 82% of adults are unaware of the dangers that infectious bacteria play in mouth disease, ... times a day that dentists recommend. The ramifications of improper oral upkeep go far beyond ... missing 164 million hours of work each year due to dental issues. That is why ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... release of SmartBen NOW, an innovative mobile app and centralized benefits dashboard solving ... present critical information securely from multiple locations. For the first time, employees can ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... surveys with 9,250 insured consumers fielded from February 2015 ... help from their plans in five key areas: 1) ... help closing gaps in care, 3) better digital connections, ... real-time guidance. Meeting these needs is essential to promoting ... A Reason to Stay Engaged in Health ...
(Date:3/23/2017)... Research and Markets has announced the addition of the ... report to their offering. ... The Global Cryostat Market is poised to grow ... reach approximately $3.5 billion by 2025. This industry report ... on global as well as regional levels presented in the research ...
(Date:3/23/2017)... LONDON , March 23, 2017 ... comprehensive research report created through extensive primary research ... research, the report aims to present the analysis ... basis of Procedure (Replacement and Repair); Replacement Procedure ... (TAVR)), Repair By Technique (Surgical Devices, Balloon Valvuloplasty, ...
Breaking Medicine Technology: