Navigation Links
Breakthrough in treatment to prevent blindness
Date:12/21/2011

A UCSF study shows a popular treatment for a potentially blinding eye infection is just as effective if given every six months versus annually. This randomized study on trachoma, the leading cause of infection-caused blindness in the world, could potentially treat twice the number of patients using the same amount of medication.

"The idea is we can do more with less," said Bruce Gaynor, MD, assistant professor of ophthalmology at the Francis I. Proctor Foundation for Research in Ophthalmology. "We are trying to get as much out of the medicine as we can because of the cost and the repercussions of mass treatments."

In a paper published this month in The Lancet, researchers conducted a cluster-randomized trial, using an antibiotic called azithromycin to treat trachoma in Ethiopia, which has among the highest prevalence in the world. They picked 24 communities and randomized the two treatment options: 12 villages were given azithromycin every six months and the other 12 were treated every 12 months.

"What we found was the prevalence of trachoma is very high at baseline. Forty to 50 percent of the children in these communities have this condition," Gaynor said. "They are the most susceptible and it can quickly spread from person to person by direct or even indirect contact."

Researchers tracked both groups and found the prevalence of infection decreased dramatically.

"We found that from as high as 40 percent, the prevalence of trachoma went way down, even eliminated in some villages regardless of whether it was treated in an annual way or a biannual way," Gaynor said. "You can genuinely get same with less."

Their finding is significant because of how easily the disease spreads. Trachoma can be transmitted through touching one's eyes or nose after being in close contact with someone who is infected. It can also be spread through a towel or an article of clothing from a person who has trachoma. Even flies can transmit the disease.

Approximately 41 million people are infected with trachoma globally, and 8 million go blind because of lack of access to treatment. More than 150 million doses of azithromycin have been given out worldwide to treat this disease. Unlike other antibiotics, resistance to azithromycin has not been found in Chlamydia trachomatis, the bacteria that causes trachoma.

This and the paper's major finding give hope to Africa, Asia, the Middle East, and parts of Latin America and Australia, where trachoma is still a major problem.

"We will now be able to reach more people and make the treatment go twice as far as before," Gaynor said. "This will make a huge impact in slowing down trachoma-related blindness globally."


'/>"/>
Contact: Leland Kim
leland.kim@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Related medicine news :

1. 2011 ASH Annual Meeting to highlight latest hematology research, clinical care breakthroughs
2. Cleveland researchers find possible breakthrough to relieve pain following spinal cord injury
3. Princeton technique puts chemistry breakthroughs on the fast track
4. 2 breakthrough innovations to address maternal and newborn deaths in Sub-Saharan Africa
5. Indevr launches breakthrough colorimetric detection for microarrays using core technology from CU
6. Ben-Gurion University of the Negev researchers achieve male fertility breakthrough
7. Breakthrough in understanding the genetics of high blood pressure
8. Northern Ireland company makes major breakthrough in cancer treatment
9. An important breakthrough at the IRCM associated with osteoporosis
10. Identification and management of breakthrough cancer pain remains a challenge
11. Childrens National researchers make breakthrough in understanding white matter development
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough in treatment to prevent blindness
(Date:2/9/2016)... ... , ... On January 12, 2016 Paul McElwee, a CroppMetcalfe HVAC technician, visited ... not producing any heat. Shortly after entering the home, Paul was able to identify ... levels of carbon monoxide into the home, at 2,000 parts per million in the ...
(Date:2/9/2016)... , ... February 09, 2016 , ... Dr. Rassouli, ... packages. Teeth whitening is among the most popular cosmetic procedures in dentistry today, but ... needs. This can put them at risk of teeth whitening-related damage. For a limited ...
(Date:2/9/2016)... Florida (PRWEB) , ... February 09, 2016 , ... ... cold therapy products, announced today the introduction of the newly designed, innovative shoulder ... comfort and better cold therapy coverage for the injured arm and shoulder to ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... and sealing company , is proud to announce that many of their franchises ... of customer service. The hard surface restoration franchises received customer recognition through positive ...
(Date:2/9/2016)... ... February 09, 2016 , ... The ... been won. A team from 21st Century Medicine (21CM) ( http://www.21cm.com/ ), ... the delicate neural circuits of an intact rabbit brain for extremely long-term storage ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... The new report "Global Anti-Bacterial Drugs Market Assessment & Forecast: 2015 ... that the North America continued to lead ... that translated into revenues worth US$ 16,907.3 million. ... Asia-Pacific , Latin America , ... global anti-bacterial market is inclined towards North America ...
(Date:2/8/2016)... , Feb.8, 2016 Alzheimer Diagnostic ... Summary Medical Devices sector report , ... 2015" provides an overview of Alzheimer Diagnostic Tests ... comprehensive information on the pipeline products with comparative ... development. The report reviews major players involved in ...
(Date:2/8/2016)... , Feb. 8, 2016  Labvantage Lx, a ... its first male sexual enhancement product, EnduramenT. Setting ... proven ethnobotanicals with a patented biomedical breakthrough molecule ... the chemical compound responsible for many biological functions ... Forgoing the use of prescription ...
Breaking Medicine Technology: