Navigation Links
Breakthrough in Alzheimer's research
Date:8/12/2009

A combination of proteins in the cerebrospinal fluid can reliably identify which patients with early symptoms of dementia will subsequently develop full-blown Alzheimer's disease, a research team at the University of Gothenburg, Sweden, has found in a major international study. The results were published in this week's edition of the Journal of the American Medical Association (JAMA).

Alzheimer's is one of the most common dementia disorders. Around 160,000 people in Sweden currently suffer from dementia, and an estimated 60 per cent of them have Alzheimer's.

"There is currently no medication that can alter the course of the disease, but the medicines currently under development will probably have the greatest effect if they are used from an early stage, so methods are needed for early diagnosis of the disease," says Dr Niklas Mattsson, a member of Kaj Blennow's group at the Institute of Neuroscience and Physiology at the University of Gothenburg's Sahlgrenska Academy.

Changes in the brain are reflected in the cerebrospinal fluid (CSF) in the form of biomarkers. Previous smaller studies have shown that the proteins beta-amyloid, tau and phosphorylated tau in the CSF can be used to make an early diagnosis of Alzheimer's.

Now Mattsson and colleagues at hospitals in Sweden, elsewhere in Europe and the USA have confirmed this in a large multicentre study with more than 1,500 participants.

"These methods make it easier to identify the disease, which is essential for making a correct diagnosis early on," he says. "These biomarkers may be useful both in research to develop new medicines and in point-of-care diagnostics, where they can support clinical diagnostics."

So when will we see new medicines?

"I'm reluctant to speculate, but there is a lot of exciting research under way, and new medicines are under development."


'/>"/>

Contact: Niklas Mattsson
Niklas.Mattsson@neuro.gu.se
46-317-863-869
University of Gothenburg
Source:Eurekalert  

Page: 1

Related medicine news :

1. Breakthrough Nursing Home Alternative Now Available to Cincinnati Elders and Their Families at Deupree Cottages
2. Los Angeles Cosmetic Dentist Sam Muslins Breakthrough Procedure: Face Lift Dentistry
3. Brooks Instrument Introduces New Liquid Vaporizer Solutions Breakthrough Vaporization Solutions for All Liquid-to-vapor Applications
4. Genetic Breakthrough Spells Hope for Lung Fibrosis Patients
5. Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
6. Breakthrough in combating the side effects of quinine
7. Veran Medical Enables Breakthrough 4D Navigation to Cancer Lesions at University of Virginia Hospital
8. UGA researchers achieve breakthrough in effort to develop tiny biological fuel cells
9. Leaders from the Field of Pain Therapeutics to Discuss Latest Discoveries and Breakthroughs at Arrowhead's 3rd Annual Pain Therapeutics Summit
10. Another McGill/JGH breakthrough opens door to early Alzheimers diagnosis
11. Breakthrough Testing For Early Heart Disease - In the Doctor's Office
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough in Alzheimer's research
(Date:3/22/2017)... ... 22, 2017 , ... Drs. Jennifer Houck, Lauren Smith, Heather Johnson and the ... in need of skilled pediatric dentistry in Rock Hill, SC, without a ... routine treatments, including cavities, sealants and fluoride applications, in a comfortable and fun environment. ...
(Date:3/22/2017)... ... March 22, 2017 , ... The Carballo Agency, a comprehensive ... New York metropolitan region, is embarking on a cooperative charity drive with Family ... present, more than two and a half million children in the United States ...
(Date:3/22/2017)... ... 2017 , ... Schneider Insurance and Financial, a southern Montana firm providing asset ... region, is launching a charity event aimed at raising local support for Zoo Montana. ... State, and is home to a broad variety of animals from all over the ...
(Date:3/22/2017)... ... March 22, 2017 , ... The Senior Citizens ... and prevent a default on the federal debt — including the debt held by ... growing concern, ” said TSCL in a letter to House and Senate budget leaders. ...
(Date:3/22/2017)... (PRWEB) , ... March 22, 2017 , ... Sharon Kleyne ... created more than two decades ago to research evaporation of earth’s and the body’s ... promotes better health. Also the host of the nationally syndicated radio program, The Sharon ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... MAPLE GROVE, Minn. , March 22, 2017   ... of Clomipramine Hydrochloride Capsules* USP, 25 mg, 50 mg and ... (clomipramine hydrochloride) Capsules USP. The clomipramine ... for the 12 months ending December 2016, according to IMS ... ...
(Date:3/22/2017)... 2017  Levine Cancer Institute today launched the ... to address lung cancer diagnosis, treatment and survival ... mobile lung unit is the first-of-its-kind to link ... interventions through integrated mobile technology, traditional treatment facilities ... and a lack of public transportation are barriers ...
(Date:3/22/2017)... 22, 2017  Varex Imaging Corporation (Nasdaq: ... renewed three-year pricing agreement with Toshiba Medical Systems under ... tomography (CT) tubes for integration into Toshiba Medical,s CT ... will be effective April 1, 2017. Potential ... are estimated to be in the range of $345 ...
Breaking Medicine Technology: