Navigation Links
Breakthrough by Danish scientists in preventing maternal malaria
Date:2/4/2010

Researchers at the University of Copenhagen have become the first in the world to synthesize the entire protein that is responsible for life-threatening malaria in pregnant women and their unborn children. The protein known as VAR2CSA enables malaria parasites to accumulate in the placenta and can therefore potentially be used as the main component in a vaccine to trigger antibodies that protect pregnant women against malaria. The research team is now planning to test the efficacy of the protein-based vaccine on humans. The hope is that within 10 years all African girls could be vaccinated against maternal malaria, thereby preventing more than 200,000 deaths a year.

Each year, 25 million pregnant women in sub-Saharan Africa run the risk of contracting malaria. Women who have become infected with malaria parasites during their first pregnancy are at considerable risk of severe anaemia and significant impairment of foetal growth. The malaria parasites accumulate in the placenta, resulting in children being born prematurely and underweight. These women are also at greater risk of dying during pregnancy and childbirth. Maternal malaria is the cause of death of between 100,000 and 200,000 newborn babies and 10,000 women each year.

"The malaria research group discovered the protein VAR2CSA, which is responsible for malaria parasite binding in the placenta, in 2003," says Associate Professor Ali Salanti from the centre. "The aim is to produce a vaccine based on VAR2CSA which elicits antibodies that stop the parasite from binding to the placenta. The challenge for us has been to produce the entire protein in the laboratory, as it is very large and so technically complex. Now that we've managed to do this, we're a big step closer to developing a human vaccine, as we can already test it as a vaccine in animals."

"In collaboration with scientists at The Tanzanian National Institute for Medical Research, we've tested the antibodies that were
'/>"/>

Contact: Sandra Szivos
sasz@sund.ku.dk
453-532-6921
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related medicine news :

1. On 30th Anniversary, Angioplasty Celebrated as Modern Medical Breakthrough in Stopping Heart Attack
2. drugstore.com and Revolution Health Group Announce Breakthrough Deal
3. New Round of Lupus Research Institute Awards Brings Promise of More Breakthroughs
4. CBaySystems Introduces CBayPraxis - A Breakthrough Solution Focused on Physician Practice Efficiency
5. Oosight Imaging System Enables a Breakthrough: The Viable Transfer of Genetic Material for Stem Cell Nuclear Reprogramming in Primates
6. Breakthrough in organ rejection diagnosis examines gene behavior
7. Safe Sex Passport Launches to Provide Breakthrough Protection Against STDs and HIV
8. Major breakthrough toward the treatment of HIV/HAART-associated Lipodystrophy Syndrome
9. Cardica Announces Live Webcast Demonstrating Breakthrough Device to Facilitate Beating Heart and Robotic Coronary Revascularization Surgery
10. TIME Magazine Names GeneSearch(TM) One of the Top 10 Medical Breakthroughs in 2007
11. California Breakthrough a Pivotal Moment in Fight to Transform Nations Health Care System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Most dentists work during normal business hours. That ... their day to be able to go see the dentist. ... a few hours during their increasingly busy days. That is ... It is now possible for people to get the preventative ... happening? , North York Dental has realized that it is ...
(Date:8/29/2014)... The Florida Chiropractic Association held its National ... week August 21-24 and Maryland and Virginia chiropractor ... , Dr. Greenstein presented at three different sessions: ... standing room session; (2) A Panelist at the Plenary ... the Way in Injury Prevention and Maximizing Human Performance; ...
(Date:8/29/2014)... Recent reports, backed by the US ... are working longer hours and taking fewer vacations than ... believes that drinking lots of purified water can help, ... their most popular and effective water purification systems to ... 9/2/2014, customers can save up to $125 off all ...
(Date:8/29/2014)... Auckland, NZ (PRWEB) August 29, 2014 ... of Greg Allen to Chief Executive Officer effective from ... Chief Technology Officer for Winscribe. , “During this time ... Winscribe than Greg Allen,” said Matthew Weavers, Winscribe’s Founder ... leader with a wealth of commercial, IT and management ...
(Date:8/28/2014)... Peoria, Illinois (PRWEB) August 29, 2014 ... of feeling tired all the time, twenty percent of ... to interfere with their daily life. Adrenal Fatigue is ... if you have more of the classic symptoms. Tasks ... flairs up over things that previously didn’t cause irritation, ...
Breaking Medicine News(10 mins):Health News:North York Dental Provides Dental Services to Busy Professionals 2Health News:Sport and Spine Rehab’s CEO Presents at the Florida Chiropractic Association National Convention and Expo 2014 2Health News:Relax this Labor Day Weekend with Great Savings on Easy-Install, Do-It-Yourself Drinking and Whole House Water Filters 2Health News:Winscribe Names Greg Allen as CEO 2Health News:Peoria AlignLife Clinics Focus on Community Education 2
... between tests, researchers say , THURSDAY, Oct. 4 (HealthDay ... DNA testing enables earlier detection of lesions that lead ... women could go longer between screenings, say researchers at ... study included more than 17,000 women ages 29 to ...
... Onyx,Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced ... to retire next year.,Renton, 60, will remain chairman of ... the company is initiating a search for a successor. ... to the newly created,position of executive vice president & ...
... Inc.,(Nasdaq: ANSV ) today announced that it ... review the company,s launch and commercialization,plans for Zingo(TM) ... will take place on Friday,October 12, 2007 from ... York City. To,access the live audio broadcast or ...
... the,November 2006 Rand Corp. study, health care provided ... a year nationally and that 68,percent of illegal ... of millions of newcomers, U.S.-born and foreign-born relatives ... to the U.S. population.,They will also consume energy, ...
... ANA, Calif., Oct. 4 More than 35,million children ... the streets in,costume this Halloween. Although hours of planning ... people fail to consider,the importance of security. "Today, most ... in a sealed wrapper and safe to eat," says ...
... ... organizations, ST. PAUL, Minn., Oct. ... announced today it has,achieved URAC Pharmacy Benefit Management (PBM) accreditation. ... practices, promote quality improvement and protect and,empower consumers. Prime began its ...
Cached Medicine News:Health News:Gene-Based Screen Spots Cervical Cancer Earlier 2Health News:Onyx Pharmaceuticals Announces Management Changes 2Health News:Onyx Pharmaceuticals Announces Management Changes 3Health News:Anesiva to Unveil Zingo(TM) Commercialization Plans 2Health News:Message for Activists at Latino National Congreso Convention: Amnesty Will Exacerbate National Problems and Turn the U.S. into Another Mexico 2Health News:Safety Tips for a Fun and Spooky Halloween 2Health News:Prime Therapeutics Announces URAC Accreditation 2
(Date:8/28/2014)... Resources Group finds that the market for colorectal cancer (CRC) ... in the United States , ... Italy , Spain , the ... . The biosimilar erosion of Roche/Genentech/Chugai,s Avastin and Bristol-Myers Squibb/Eli ... of Eli Lilly,s Cyramza, Taiho Pharmaceutical,s Lonsurf, Alchemia,s HA-irinotecan and ...
(Date:8/28/2014)... YORK , Aug. 28, 2014 Levi ... been commenced in the United States District Court for ... behalf of investors who purchased Galectin Therapeutics Inc. ("Galectin" ... 2014 and July 28, 2014. For more ... complaint alleges that during the Class Period the Company ...
(Date:8/28/2014)... , Aug. 28, 2014 Nonin Medical, ... leader in noninvasive medical monitoring, today announced that the ... Model 3231 OEM/eHealth finger pulse oximeter for use in ... pulse oximeter plugs into a telemedicine hub or kiosk ... pulse rate in pediatric to adult patients. The Model ...
Breaking Medicine Technology:The Colorectal Cancer Market Will Remain Steady at $7.7 Billion by 2023, With Biosimilar Erosion Of Key Agents Being Balanced Out By the Launch Of Premium-Priced Therapies 2SHAREHOLDER ALERT: Levi & Korsinsky, LLP Reminds Investors of Class Action Against Galectin Therapeutics Inc. and Its Board of Directors and a Lead Plaintiff Deadline of September 29, 2014 -- GALT 2Nonin Medical Announces FDA Clearance of Nonin Model 3231 USB Pulse Oximeter 2
... and Company (NYSE: LLY ) today issued ... and chief executive officer about his meeting today with ... job creation, American innovation and competiveness: "It,s ... and take part in this very important dialogue today ...
... Dec. 15, 2010 Johnson & Johnson (NYSE: ... Worldwide Chairman, Medical Devices & Diagnostics (MD&D) and Sheri ... Chairmen of the Executive Committee and join William C. ... in an expanded Office of the Chairman.  Both appointments ...
Cached Medicine Technology:Lilly Statement Regarding President Obama's Meeting With U.S. Business Leaders 2Johnson & Johnson Announces Executive Appointments: Alex Gorsky, Vice Chairman, Executive Committee Sheri McCoy, Vice Chairman, Executive Committee 2Johnson & Johnson Announces Executive Appointments: Alex Gorsky, Vice Chairman, Executive Committee Sheri McCoy, Vice Chairman, Executive Committee 3
Colorimetric Assay of Antithrombin III Activity by STA© Analyzers. Bovine thrombin ~12NIH units/mL, freeze-dried....
Immuno-turbidimetric assay for Free Protein Sby STA© Analyzers. Suspension of microparticles coated with monoclonal antibodies to Free Protein S....
Colorimetric Assay of Unfractionated and Low Molecular Weight Heparins by STA© Analyzers. Lyophilized, patent-pending chromogenic substate, CBS 52.44 of ~4.2 moles/vial and bovine factor Xa ~1.1...
Substrate Plasma for Factor VII Assay by STA© Analyzers. Freeze-dried human plasma from which factor VII has been removed by selective immuno-adsorption....
Medicine Products: