Navigation Links
Breakthrough Research Provides Valuable Insight On Cause Of Alzheimer’s
Date:1/8/2014

New York, NY (PRWEB) January 08, 2014

A stem cell model of familial Alzheimer’s disease (FAD) was successfully generated, allowing researchers to identify 14 genes potentially implicated in the disease. One gene in particular demonstrates the important role inflammation may play in the brain of Alzheimer’s patients. The study was completed by scientists at The New York Stem Cell Foundation (NYSCF) Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) and funded in part by the Cure Alzheimer’s Fund(CAF).

In the study published today in PLOS ONE, a team of scientists produced stem cells and neural precursor cells (NPCs), representing early neural progenitor cells that build the brain from patients with severe early-onset AD with mutations in the Presenilin 1 (PSEN1) gene. These NPCs had elevated Abeta42/Abeta40 ratios, indicating elevation of the form of amyloid found in the brains of Alzheimer’s patients. These levels were greater than those in adult cells that did not have the PSEN1 mutation. This elevated ratio shows that the NPCs grown in the petri dish accurately reflected the cells in the brains of FAD patients.

"The gene expression profile from the familial Alzheimer’s stem cells points to inflammation, which is especially exciting because we would not usually associate inflammation with this particular Alzheimer's gene," said Sam Gandy, MD, PhD, Professor of Neurology and Psychiatry and Director of the Center for Cognitive Health at the Icahn School of Medicine at Mount Sinai and a co-author on the study. Gandy is also Associate Director of the NIH-Designated Mount Sinai Alzheimer’s Disease Research Center and leader of the

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Diverticulitis Breakthrough Review Indicates If This Book Is Reliable – HealthReviewCenter
2. MD Anderson researcher Jim Allison wins Breakthrough Prize for his innovative cancer immunology rese
3. Breakthrough in treating leukemia, lymphoma with umbilical cord blood stem cells
4. Pacific Northwest Dry Eye Sufferers Gain Access to Breakthrough Treatment at Specialty Eyecare Group
5. Noted Experts to Lead Breakthrough Conversation at Center for Hispanic Leadership, December 2nd Hispanics in Healthcare Forum
6. Study reveals potential breakthrough in hearing technology
7. Children’s Cancer & Blood Foundation Breakthrough Ball Gala Honored Margo & John Catsimatidis, Amar’e Stoudemire and Dr. Patricia J. Giardina
8. Effective and Safe Cancer Vaccine? Breakthrough Alternative Cancer Treatment Available Through Special Research Program
9. Voices Against Brain Cancer Comments On Breakthrough Brain Surgery Technique
10. Breakthrough offers first direct measurement of spinal cord myelin in multiple sclerosis
11. Voices Against Brain Cancer Discusses Possible Breakthrough in Brain Cancer Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... In the upbeat Moms Helping Moms video, ... to support each other. Parenting is a tough job, ... it so much easier. Mothers talk about how relating ... alone and help them realize there’s no perfect parent; everyone ... are clearly dear friends share that it's just that, the ...
(Date:5/5/2015)... 2015 Major League Ultimate (MLU) was ... that ultimate Frisbee™ is home to many amazing athletes, ... engages the world. Nike Ultimate Camps’ goal of spreading ... for young athletes to learn about the sport and ... perfect fit. , The Nike Ultimate Camp in Philadelphia ...
(Date:5/5/2015)... May 05, 2015 Buckeye Health Plan ... new CEO and plan president of Buckeye Health Plan. ... the position immediately. , Hill has more than 28 ... the Pacific Northwest, from managed care to large health ... and CEO of HealthPlus of Michigan, a health plan ...
(Date:5/5/2015)... Igantia , an emerging biotechnology and ... initiative to examine key biological milestones during a woman’s ... Scientists at Igantia believe that better understanding of the ... her menstrual cycle to her transition into menopause, they ... extend the lifespan. , By recently announcing the ...
(Date:5/5/2015)... 05, 2015 HealthSlide, Inc ... interoperability solutions for hospitals nationwide, has announced the ... Hospital CIOs and CTOs can access the calculator ... shows both initial and ongoing savings of switching ... “Our nation’s hospitals pay an average of $300,000 ...
Breaking Medicine News(10 mins):Health News:Just In Time For Mother’s Day, Healthy Birth Day Releases Video Titled “Moms Helping Moms” Encouraging Mothers To Band Together 2Health News:US Sports Camps, Nike Ultimate Camps, and Major League Ultimate Host Youth Ultimate Summer Camps in Philidelphia 2Health News:Buckeye Health Plan Announces New Chief Executive Officer 2Health News:Buckeye Health Plan Announces New Chief Executive Officer 3Health News:Igantia Announces Digital Initiative to Decode Longevity 2Health News:HealthSlide Launches ROI Cost Calculator 2
... to the active ingredient in marijuana but produced naturally ... may offer a novel target for treating Parkinson's disease. ... in the latest issue of the journal Nature, show ... used in the brain to transmit signals - form ...
... the February issue of Current Directions in Psychological Science ... pass on his genes during post-copulation as well, a ... Todd Shackelford and Aaron Getz at Florida Atlantic University ... competing for fertilizations." ,For a monogamous ...
... of Health of Jamaica has confirmed 280 cases of malaria ... 2006 and 3 February 2007. Of these reported cases, 264 ... in St Thomas and 1 in Clarendon. There have been ... of Health is receiving technical cooperation from the WHO Regional ...
... Todaro was talking to researchers at the Fred Hutchinson Cancer Research ... growth by slowing the rate at which tumor cells divide. ... reaction in reverse and get cells to grow faster? ... up with techniques for increasing crop yields with canola, corn and ...
... and thought to hold great promise at overcoming the ... useful for helping women with the condition achieve pregnancy ... clomiphene, report researchers in an NIH research network. ... yet to compare the two drugs in helping women ...
... link between zinc supplementation and reduced atherosclerosis in rabbit ... to their hypothesis that the effect may be due ... ,Researchers from the National University of Singapore reported ... year that supplementation of a high cholesterol diet with ...
Cached Medicine News:Health News:Natural Brain Substance Linked to Parkinson's Symptoms 2Health News:Males Adapt To Battle With Competing Sperm 2Health News:Cancer Research May Help Biofuels 2Health News:Standard Therapy More Effective in Common Fertility Disorder 2Health News:Standard Therapy More Effective in Common Fertility Disorder 3Health News:More Support for Zinc-antiatherogenic Link 2Health News:More Support for Zinc-antiatherogenic Link 3
(Date:5/5/2015)... , May 5, 2015  IQPC,s 19 th ... to announce the chairman of the Summit Mr. Phani ... He will be joined by the expert speaker faculty including ... this May 11 – 12, at The Hotel Kabuki in ... agenda is available for download on the event website, which ...
(Date:5/5/2015)... May 5, 2015  Accuray Incorporated (Nasdaq: ARAY ... the Bank of America Merrill Lynch 2015 Healthcare Conference ... May 12, 2015 at 2:20pm PT.   ... on the Investor Relations page of the Company,s website ... presentation will begin approximately one hour after the conclusion ...
(Date:5/5/2015)... -- Image Stream Medical, a leader in OR video collaboration ... the largest group purchasing organizations, serving four out of ... the three-year agreement, Image Stream,s portfolio of EasySuite™ OR ... to MedAssets members beginning on July 1, 2015. ... Eddie Mitchell said, "We ...
Breaking Medicine Technology:Phani Bidarahalli from Wipro to chair the upcoming 19th Software Design for Medical Devices Summit in San Francisco 2Image Stream Medical Announces Agreement with MedAssets 2
... Sosei Group Corporation,("Sosei"; TSE Mothers Index: 4565), ... Japanese Phase III clinical trial for the,emergency contraceptive ... rights to the product in Japan from HRA ... evaluate the safety and prevented,pregnancy rate of SOH-075 ...
... Americans, WASHINGTON, July 9 In a congressional,hearing ... the,safety and importance of the research programs operated by ... absolute commitment to its patients,while expressing regret that even ... "VA has an outstanding research program, and has been ...
Cached Medicine Technology:Sosei Announces Completion of Phase III Trial for NorLevo(R) 2Secretary Reinforces VA's Commitment to Research Safety and Veteran Focus 2Secretary Reinforces VA's Commitment to Research Safety and Veteran Focus 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: