Navigation Links
Breaking the backbone of triple-negative breast cancers
Date:3/19/2012

Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study published on March 19th in the Journal of Experimental Medicine.

Triple-negative breast tumors lack all of the known growth receptors that serve as treatment targets in other types of breast cancer, making this the most clinically challenging subtype of the disease. Patients with these tumors tend to relapse earlier and have shorter disease-free survival.

Andrei Goga and colleagues now show that triple-negative breast tumors express elevated levels of the growth-driving protein called MYC. MYC activity was required for the growth of these aggressive tumors, and blocking a MYC-cooperating protein, CDK, caused triple-negative tumors to shrink in mice.

Together, these results identify a potential new target for triple-negative tumor treatment.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Groundbreaking Principal and Contributor on Dr. Oz Show Releases His Latest Book on How We Can Influence the Lives of Children
2. Live access to breaking news from the American Stroke Association’s International Stroke Conference 2010
3. Texas-based consortium announces groundbreaking vaccine research program
4. $250,000 grant awarded for groundbreaking ligament and tendon repair research
5. $250,000 Grant Awarded for Groundbreaking Ligament and Tendon Repair Research
6. Groundbreaking Study Using Ultrasound for the Treatment of Intracerebral and Intraventricular Hemorrhage Stroke Shows Promise
7. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
8. American Stroke Association Late-Breaking Science News Report: Stroke Survivors Can Improve Functioning of Paralyzed Arm Years After Stroke
9. Groundbreaking research to find vaccine for hepatitis C
10. Special Session Highlights Late-Breaking Abstracts
11. Business Book Author is Breaking All the Rules and Utilizing Social Media in a Way that Has Never Been Done Before
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... ... research and education, today announced that it has named Scott Santarella as its ... J. Addario Lung Cancer Foundation (ALCF) in San Francisco, where he successfully helped ...
(Date:5/24/2016)... ... ... After graduating from Cornell, author Joshua Alexander was diagnosed with ... on Social Security disability and staying in a group home. In “ Healing Schizoaffective ... Balboa Press), Alexander shares how he was finally able to heal with the help ...
(Date:5/24/2016)... ... 2016 , ... PhysicianOne Urgent Care, advocators in helping their patients lead the ... avoid being bitten this spring. , The official tick season kicks off in ... are known for attaching themselves to their prey while they feed off their blood. ...
(Date:5/24/2016)... Lafayette, Colorado (PRWEB) , ... May 24, 2016 ... ... landscape architecture firm, announces the grand opening of ‘El Centro del Quinto Sol ... citizens of the Pueblo ‘east side’ community to offer something special for this ...
(Date:5/24/2016)... CA (PRWEB) , ... May 24, 2016 , ... ... cell imaging; high content imaging; multiplex immunoassays are widely used for cell and ... for labs to maximize their quality and efficiency in these areas. , LabRoots ...
Breaking Medicine News(10 mins):
(Date:5/19/2016)... According to a new market research report "Sunitinib Malate ... Germany , France , U.K., ... Japan )", published by MarketsandMarkets, The market is projected to ... from 2016 to 2021.      (Logo: http://photos.prnewswire.com/prnh/20160303/792302 ... through 26 Pages and in-depth TOC on "Sunitinib Malate ...
(Date:5/19/2016)... AVIV, Israel , May 19, 2016 ... or the "Company"), an emerging global ophthalmic company focused ... product candidates which address ophthalmic conditions, announced today that ... Italy ) for the manufacturing, distribution, ... product for the treatment of dry eye syndrome (DES) ...
(Date:5/19/2016)... May 19, 2016 At the 18 ... Meeting in Amsterdam , (May 15-19), Elekta ... clinically-proven radiosurgery system available, has been used in the ... brain tumors, vascular malformations and functional disorders. ... 75,000 patients every year in hundreds of leading hospitals ...
Breaking Medicine Technology: