Navigation Links
Brain's Serotonin May Explain Seasonal Mood Changes
Date:9/2/2008

Higher binding potential in winter could clarify why people feel down when sun shines less

TUESDAY, Sept. 2 (HealthDay News) -- Fluctuations in the actions of the serotonin transporter, which helps regulate the mood-altering neurotransmitter serotonin, may help explain seasonal affective disorder and related mood changes, researchers say.

In places where the weather changes with the seasons, people commonly feel happier and more energetic when the days are bright and sunny and more depressed and fatigued during the dark of winter. Scientists believe this is related to variations in brain levels of serotonin, a neurotransmitter involved in regulating functions such as mating, feeding, energy balance, and sleep.

In a study published in the September issue of the Archives of General Psychiatry, researchers from the Centre for Addiction and Mental Health and the University of Toronto had 88 healthy people undergo a positron emission tomography (PET) scan to assess serotonin binding potential, which indicates serotonin transporter density. The higher the serotonin binding potential, the less serotonin that is circulating in the brain.

To study seasonal fluctuations of serotonin binding potential, the researchers grouped the PET scans according to the season of the scan -- fall and winter or spring and summer.

The serotonin binding potentials were significantly higher during the fall and winter months than in the spring and summer, indicating that less serotonin circulates in the brain during the darker, colder time of the year. The researchers compared their findings to meterological data and found higher values of serotonin binding potentials during times when there were fewer hours of sunlight each day.

The researchers said that higher serotonin binding potential in the winter may help explain why people report lower mood, lack of energy, fatigue, overeating, and increased sleeping during the darker seasons.

"This offers a possible explanation for the regular reoccurrence of depressive episodes in fall and winter in some vulnerable individuals," the researchers wrote.

More information

The American Academy of Family Physicians has more about seasonal affective disorder.



-- Krisha McCoy



SOURCE: JAMA/Archives journals, news release, Sept. 1, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. A new light on the brains of people with borderline personality disorder
2. Gay Men, Straight Women Have Similar Brains
3. Cooling May Not Help Injured Brains in Children
4. New stem cell therapy may aid the repair of damaged brains
5. Sleep-Deprived Brains Show Lapse in Visual Processing
6. Analysis of alcoholics brains suggests treatment target
7. Yeast gives rise to new concept: cell fuel is brains behind division
8. AgeLab Director Brings Wisdom to Aging Brains
9. Are teenage brains really different?
10. Which came first, social dominance or big brains? Wasps may tell
11. Chicago neuroscientist contributes to book on brains and baseball
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... Dallas, Texas (PRWEB) , ... February 05, 2016 , ... ... to allow users to search for and donate to Give To Cure’s campaign ... is an app that lets users make and share payments through a smart device. ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Dr. Justin Scott ... their 2nd Annual No Cost Dental Day to individuals in need. The event is ... of this No Cost Dental Day is to provide dental care to community members ...
(Date:2/5/2016)... ... February 05, 2016 , ... In sleep, when the defenses of ... A hallmark feature of patients with eating disorders is significant self-criticism, and consequently these ... and obsessions are regarded as maladaptive means for coping with this unease, but also ...
(Date:2/5/2016)... ... ... Calls Blacklist has just been updated by mobile app developer Vlad Lee. The ... known bugs within the app. Calls Blacklist allows its users to only have to ... their device’s battery power or memory. It provides a powerful call blocker that is ...
(Date:2/5/2016)... Robles, CA (PRWEB) , ... February 05, 2016 , ... When one is tired of ... be a lifesaver. There are many reasons to rent a storage unit, but before hastily ... service to many; sometimes you simply need more space. But what one is often not ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016 Wegener Polyangiitis - Pipeline Review, ... ,Wegener Polyangiitis - Pipeline Review, H2 2015, provides ... This report provides comprehensive information on the ... analysis at various stages, therapeutics assessment by drug ... (RoA) and molecule type, along with latest updates, ...
(Date:2/4/2016)... -- Summary Breast cancer, a malignant neoplasm, is ... cancer in women worldwide, accounting for 16% of all ... of women diagnosed with breast cancer has increased over ... has declined due to earlier diagnosis and better treatment ... the past four decades, especially with increasing usage of ...
(Date:2/4/2016)... Frontier Pharma: Chronic Obstructive Pulmonary Disease ... Chronic Obstructive Pulmonary Disease (COPD) is ... the airways and lungs. Persistent breathing difficulties and ... one of the leading causes of morbidity and ... COPD is linked to cumulative exposure to risk ...
Breaking Medicine Technology: