Navigation Links
Brain's Serotonin May Explain Seasonal Mood Changes
Date:9/2/2008

Higher binding potential in winter could clarify why people feel down when sun shines less

TUESDAY, Sept. 2 (HealthDay News) -- Fluctuations in the actions of the serotonin transporter, which helps regulate the mood-altering neurotransmitter serotonin, may help explain seasonal affective disorder and related mood changes, researchers say.

In places where the weather changes with the seasons, people commonly feel happier and more energetic when the days are bright and sunny and more depressed and fatigued during the dark of winter. Scientists believe this is related to variations in brain levels of serotonin, a neurotransmitter involved in regulating functions such as mating, feeding, energy balance, and sleep.

In a study published in the September issue of the Archives of General Psychiatry, researchers from the Centre for Addiction and Mental Health and the University of Toronto had 88 healthy people undergo a positron emission tomography (PET) scan to assess serotonin binding potential, which indicates serotonin transporter density. The higher the serotonin binding potential, the less serotonin that is circulating in the brain.

To study seasonal fluctuations of serotonin binding potential, the researchers grouped the PET scans according to the season of the scan -- fall and winter or spring and summer.

The serotonin binding potentials were significantly higher during the fall and winter months than in the spring and summer, indicating that less serotonin circulates in the brain during the darker, colder time of the year. The researchers compared their findings to meterological data and found higher values of serotonin binding potentials during times when there were fewer hours of sunlight each day.

The researchers said that higher serotonin binding potential in the winter may help explain why people report lower mood, lack of energy, fatigue, overeating, and increased sleeping during the darker seasons.

"This offers a possible explanation for the regular reoccurrence of depressive episodes in fall and winter in some vulnerable individuals," the researchers wrote.

More information

The American Academy of Family Physicians has more about seasonal affective disorder.



-- Krisha McCoy



SOURCE: JAMA/Archives journals, news release, Sept. 1, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. A new light on the brains of people with borderline personality disorder
2. Gay Men, Straight Women Have Similar Brains
3. Cooling May Not Help Injured Brains in Children
4. New stem cell therapy may aid the repair of damaged brains
5. Sleep-Deprived Brains Show Lapse in Visual Processing
6. Analysis of alcoholics brains suggests treatment target
7. Yeast gives rise to new concept: cell fuel is brains behind division
8. AgeLab Director Brings Wisdom to Aging Brains
9. Are teenage brains really different?
10. Which came first, social dominance or big brains? Wasps may tell
11. Chicago neuroscientist contributes to book on brains and baseball
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... 18, 2017 , ... President Donald Trump signed into law ... for greater public access to over-the-counter (OTC) hearing aids. , The measure enables ... without being seen by a certified and licensed audiologist. , “The American ...
(Date:8/19/2017)... ... 19, 2017 , ... Praeclarus Press has launched a ... the diversity of the breastfeeding mothers, using bright colors and contemporary themes. ... illustrations are also available on tote bags, notepads, smartphone cases, clocks, and travel ...
(Date:8/19/2017)... ... August 19, 2017 , ... Physician Partners of America Pain ... an interventional pain management physician. He brings a wealth of pain management experience ... and significant experience in spinal cord stimulation for chronic pain. , Dr. Ahmed ...
(Date:8/18/2017)... Lynchburg, VA (PRWEB) , ... August 18, 2017 , ... ... to the Democratic Republic of Congo (DRC) thanks to an ambitious venture that conjoined ... as well as the generous support of the Liberty community. These shoes will save ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... campaign, advocating for active, healthy lifestyles and highlighting the importance of proactive eye ... hearing impairments and shares the latest innovations in hearing aid technology. , ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)...   Mostyn Law and Gulf Coast Regional Blood Center ... . The Mostyn Law family has had 3 members ... why Mostyn Law is partnering with Gulf Coast Regional ... appreciation. Blood supplies are running low. Gulf Coast Regional ... needs in August. That is why the blood center reached out ...
(Date:8/14/2017)... and PETACH TIKVAH, Israel , ... BCLI), a leading developer of adult stem cell technologies ... quarter ending June 30, 2017. ... preparing for our pivotal Phase 3 trial to investigate ... , President and Chief Executive Officer of BrainStorm. "We ...
(Date:8/7/2017)... , Aug. 7, 2017 Insightin ... member acquisition, retention, and engagement, announced the selection ... Strategy and Product Development, effective as of February 2017. ... and technology implementation strategy for our clients. Wood ... experience in consulting and business analytics within the ...
Breaking Medicine Technology: