Navigation Links
Brain's 'Reward Chemical' May Help Spur Obesity
Date:10/25/2007

Fewer dopamine receptors on cells could prompt overeating, study suggests

THURSDAY, Oct. 25 (HealthDay News) -- A new study provides more evidence that dopamine -- a brain chemical associated with reward, pleasure, movement and motivation -- plays a role in obesity.

Researchers at the U.S. government's Brookhaven National Laboratory in Upton, N.Y., found that genetically obese rats have lower levels of dopamine D2 receptors on brain cells than lean rats. The study also found that restricting food intake can increase the number of D2 receptors on those cells.

"This research corroborates brain-imaging studies conducted at Brookhaven that found decreased levels of dopamine D2 receptors in obese people compared with normal-weight people," lead author and Brookhaven neuroscientist Panayotis (Peter) Thanos, said in a prepared statement.

"This study also provides further evidence for the interplay of genetic factors with the environment in the development of obesity in our society," he added.

It's not clear whether reduced dopamine D2 receptor levels are a cause or consequence of obesity, Thanos said. Overeating may cause a chronic reduction in receptor levels and, over the long term, contribute to obesity. However, genetically influenced low levels of D2 receptors may also cause obesity, because a person may overeat in an attempt to stimulate a "blunted" reward system.

In both cases, increasing dopamine D2 receptor levels by restricting food intake may prove an effective way of combating obesity, Thanos said.

"Consuming fewer calories is obviously important for people trying to lose weight, plus improving the brain's ability to respond to rewards other than food may help prevent overeating," Thanos noted.

The findings are available online and are expected to be published in an upcoming print issue of the journal Synapse.

More information

The U.S. Centers for Disease Control and Prevention has more about overweight/obesity.



-- Robert Preidt



SOURCE: Brookhaven National Laboratory, news release, Oct. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Genetic differences found between Male and Female brains
2. Babies Brains Are more Fragile
3. Fish eaters found to have sharper brains
4. Healthy Brains Depend Upon Survival Genes
5. Human neurons grown in the brains of mice
6. Hamsters Shows How Our Brains May Recognize Other Individuals
7. Brainstorming session for Bihar legislators on AIDS
8. Structural Abnormalities in Brains of William Syndrome Patients
9. Perception Stabilized – Thanks to Your Brains
10. Brain-child of Natus Medical, “Cool Cap”, Protects Brains of Babies Born With HE
11. Severe PTSD Damages Childrens Brains: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... January 19, 2017 , ... Aerolib ... system for Clinical and Regulatory education for Physicians, Physician Advisors, Case managers, ... education methodology of Disease Specific Documentation Improvement. , The Aerolib Learning Management ...
(Date:1/19/2017)... ... ... cold weather here, many people will have to clear snow with snow blowers or shovels ... but they can be dangerous when used incorrectly. That’s why Amica Insurance is ... of snow blowers:, , When removing wet snow or debris from ...
(Date:1/19/2017)... ... January 19, 2017 , ... WhoHaha , a digital media company ... Heart Association (AHA) to produce a three-part video series that uses humor to highlight ... of the launch of AHA’s Healthy For Good™ movement, which is designed to inspire ...
(Date:1/19/2017)... Park City, Utah (PRWEB) , ... January 19, ... ... Sundance Film Festival in a medical capacity this year. Drs. Alexander Paziotopoulos, Andrew ... Lounge to provide a condensed version of the clinic’s leading recovery program. ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... provided a new $11,250,000 senior credit facility to Sunrise, Florida-based Management Health Systems, ... were used to facilitate a recapitalization of MedPro led by Harren Equity Partners. ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... CLEVELAND , Jan. 18, 2017  ViewRay, ... the world,s first and only clinical MRI-guided radiation ... gross proceeds of approximately $26.1 million through a ... Puissance Capital Management led the financing and was ... OrbiMed Advisors, LLC and Kearny Venture Partners, and ...
(Date:1/19/2017)... ALAMEDA, Calif. , Jan. 18, 2017 /PRNewswire/ ... (MPI) solutions has entered into an agreement with ... for the Momentum MPI imaging system based on ... VivoQuant will be distributed as a complete MPI ... to enable quantitative nanoparticle or cell imaging in ...
(Date:1/19/2017)... , Jan. 18, 2017 The drug delivery ... by 2021 from USD 1,179.20 billion in 2016, at ... Increasing prevalence of chronic diseases, increasing demand for biologics, ... driving the growth of this market. Whereas, self-administration & ... drugs offer significant growth opportunities for players operating in ...
Breaking Medicine Technology: