Navigation Links
Brain's 'Reward Chemical' May Help Spur Obesity
Date:10/25/2007

Fewer dopamine receptors on cells could prompt overeating, study suggests

THURSDAY, Oct. 25 (HealthDay News) -- A new study provides more evidence that dopamine -- a brain chemical associated with reward, pleasure, movement and motivation -- plays a role in obesity.

Researchers at the U.S. government's Brookhaven National Laboratory in Upton, N.Y., found that genetically obese rats have lower levels of dopamine D2 receptors on brain cells than lean rats. The study also found that restricting food intake can increase the number of D2 receptors on those cells.

"This research corroborates brain-imaging studies conducted at Brookhaven that found decreased levels of dopamine D2 receptors in obese people compared with normal-weight people," lead author and Brookhaven neuroscientist Panayotis (Peter) Thanos, said in a prepared statement.

"This study also provides further evidence for the interplay of genetic factors with the environment in the development of obesity in our society," he added.

It's not clear whether reduced dopamine D2 receptor levels are a cause or consequence of obesity, Thanos said. Overeating may cause a chronic reduction in receptor levels and, over the long term, contribute to obesity. However, genetically influenced low levels of D2 receptors may also cause obesity, because a person may overeat in an attempt to stimulate a "blunted" reward system.

In both cases, increasing dopamine D2 receptor levels by restricting food intake may prove an effective way of combating obesity, Thanos said.

"Consuming fewer calories is obviously important for people trying to lose weight, plus improving the brain's ability to respond to rewards other than food may help prevent overeating," Thanos noted.

The findings are available online and are expected to be published in an upcoming print issue of the journal Synapse.

More information

The U.S. Centers for Disease Control and Prevention has more about overweight/obesity.



-- Robert Preidt



SOURCE: Brookhaven National Laboratory, news release, Oct. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Genetic differences found between Male and Female brains
2. Babies Brains Are more Fragile
3. Fish eaters found to have sharper brains
4. Healthy Brains Depend Upon Survival Genes
5. Human neurons grown in the brains of mice
6. Hamsters Shows How Our Brains May Recognize Other Individuals
7. Brainstorming session for Bihar legislators on AIDS
8. Structural Abnormalities in Brains of William Syndrome Patients
9. Perception Stabilized – Thanks to Your Brains
10. Brain-child of Natus Medical, “Cool Cap”, Protects Brains of Babies Born With HE
11. Severe PTSD Damages Childrens Brains: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Many women ... diagnosed with endometriosis. These women need a treatment plan to not only alleviate ... that can help for preservation of fertility and ultimately achieving a pregnancy. The ...
(Date:6/25/2016)... ... 25, 2016 , ... Austin residents seeking Mohs surgery services, can now turn ... to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization ... selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction ...
(Date:6/25/2016)... ... , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize ... Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into ... Simply select a ProHand generator and drag it above media or text in the ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced ... Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality ... - Global Forecast to 2021" report to their ... global pharmaceutical excipients market is projected to reach USD ... in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
Breaking Medicine Technology: