Navigation Links
Brain's 'Reward Chemical' May Help Spur Obesity
Date:10/25/2007

Fewer dopamine receptors on cells could prompt overeating, study suggests

THURSDAY, Oct. 25 (HealthDay News) -- A new study provides more evidence that dopamine -- a brain chemical associated with reward, pleasure, movement and motivation -- plays a role in obesity.

Researchers at the U.S. government's Brookhaven National Laboratory in Upton, N.Y., found that genetically obese rats have lower levels of dopamine D2 receptors on brain cells than lean rats. The study also found that restricting food intake can increase the number of D2 receptors on those cells.

"This research corroborates brain-imaging studies conducted at Brookhaven that found decreased levels of dopamine D2 receptors in obese people compared with normal-weight people," lead author and Brookhaven neuroscientist Panayotis (Peter) Thanos, said in a prepared statement.

"This study also provides further evidence for the interplay of genetic factors with the environment in the development of obesity in our society," he added.

It's not clear whether reduced dopamine D2 receptor levels are a cause or consequence of obesity, Thanos said. Overeating may cause a chronic reduction in receptor levels and, over the long term, contribute to obesity. However, genetically influenced low levels of D2 receptors may also cause obesity, because a person may overeat in an attempt to stimulate a "blunted" reward system.

In both cases, increasing dopamine D2 receptor levels by restricting food intake may prove an effective way of combating obesity, Thanos said.

"Consuming fewer calories is obviously important for people trying to lose weight, plus improving the brain's ability to respond to rewards other than food may help prevent overeating," Thanos noted.

The findings are available online and are expected to be published in an upcoming print issue of the journal Synapse.

More information

The U.S. Centers for Disease Control and Prevention has more about overweight/obesity.



-- Robert Preidt



SOURCE: Brookhaven National Laboratory, news release, Oct. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Genetic differences found between Male and Female brains
2. Babies Brains Are more Fragile
3. Fish eaters found to have sharper brains
4. Healthy Brains Depend Upon Survival Genes
5. Human neurons grown in the brains of mice
6. Hamsters Shows How Our Brains May Recognize Other Individuals
7. Brainstorming session for Bihar legislators on AIDS
8. Structural Abnormalities in Brains of William Syndrome Patients
9. Perception Stabilized – Thanks to Your Brains
10. Brain-child of Natus Medical, “Cool Cap”, Protects Brains of Babies Born With HE
11. Severe PTSD Damages Childrens Brains: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Datta Endoscopic ... has joined the revolutionary endoscopic practice under Dr. Datta. Patel is a Board ... Medicine. The patented, revolutionary eDiscSculpt Technique created and used by Datta Endoscopic is ...
(Date:4/28/2017)... ... April 28, 2017 , ... From April 30 to May ... Medicine will host industry leaders for the annual spring Convention & Expo, called ... industry adapt to the issues currently affecting urgent care and on-demand healthcare. , ...
(Date:4/28/2017)... Diego, Ca (PRWEB) , ... April 28, 2017 , ... ... property management industry in the coastal communities. After Tina Howe joined the team, the ... and happy employees, honest services at affordable rates, and giving back to the San ...
(Date:4/28/2017)... ... April 28, 2017 , ... Phytomer USA is pleased ... has 20+ years of experience within the beauty industry, ranging from marketing, retail ... of high-end cosmetic brands, retail brands and outlets in Canada and New York. ...
(Date:4/28/2017)... ... 28, 2017 , ... NuevaCare, a leading home care agency based in San ... Alto, is proud to announce information upgrades to its blog in the form of ... on topics such as home care (generally) as well as senior care and home ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... , April 20, 2017   ZappRx, Inc ., ... specialty drug prescribing process, today announced it closed $25 million ... a venture capital firm based in Seattle ... Qiming Venture Partners . The Series B round included participation ... round in 2014, and GV (formerly Google Ventures). ...
(Date:4/20/2017)... , April 20, 2017 Eyevensys, ... the first non-viral gene expression technology that enables the ... eye to address a wide range of ophthalmic diseases, ... and Healthcare products Regulatory Agency (MHRA) to advance its ... ...
Breaking Medicine Technology: