Navigation Links
Brain structure shows who is most sensitive to pain
Date:1/14/2014

WINSTON-SALEM, N.C. Jan. 14, 2014 Everybody feels pain differently, and brain structure may hold the clue to these differences.

In a study published in the current online issue of the journal Pain, scientists at Wake Forest Baptist Medical Center have shown that the brain's structure is related to how intensely people perceive pain.

"We found that individual differences in the amount of grey matter in certain regions of the brain are related to how sensitive different people are to pain," said Robert Coghill, Ph.D., professor of neurobiology and anatomy at Wake Forest Baptist and senior author of the study.

The brain is made up of both grey and white matter. Grey matter processes information much like a computer, while white matter coordinates communications between the different regions of the brain.

The research team investigated the relationship between the amount of grey matter and individual differences in pain sensitivity in 116 healthy volunteers. Pain sensitivity was tested by having participants rate the intensity of their pain when a small spot of skin on their arm or leg was heated to 120 degrees Fahrenheit. After pain sensitivity testing, participants underwent MRI scans that recorded images of their brain structure.

"Subjects with higher pain intensity ratings had less grey matter in brain regions that contribute to internal thoughts and control of attention," said Nichole Emerson, B.S., a graduate student in the Coghill lab and first author of the study. These regions include the posterior cingulate cortex, precuneus and areas of the posterior parietal cortex, she said.

The posterior cingulate cortex and precuneus are part of the default mode network, a set of connected brain regions that are associated with the free-flowing thoughts that people have while they are daydreaming.

"Default mode activity may compete with brain activity that generates an experience of pain, such that individuals with high default mode activity would have reduced sensitivity to pain," Coghill said.

Areas of the posterior parietal cortex play an important role in attention. Individuals who can best keep their attention focused may also be best at keeping pain under control, Coghill said.

"These kinds of structural differences can provide a foundation for the development of better tools for the diagnosis, classification, treatment and even prevention of pain," he said.


'/>"/>

Contact: Marguerite Beck
marbeck@wakehealth.edu
336-716-2415
Wake Forest Baptist Medical Center
Source:Eurekalert

Related medicine news :

1. Helping Children with Autism Using Brain Training Apps from C8 Sciences
2. Gene variation associated with brain atrophy in mild cognitive impairment
3. RSNA: Gene Variation Associated with Brain Atrophy in Mild Cognitive Impairment
4. Bestselling Psychobiologist's 'Your Brain on Love' Offers Tools to Forever Change the way we love
5. Multi-institutional team finds targetable mutation in rare brain tumor
6. Voices Against Brain Cancer Comments On How Boosting One’s Immune System Can Help Fight Tumor Growth
7. Mobile phones, apps, throw lifeline to sufferers of brain and mental disorders in remote world corners
8. Worker wasps grow visual brains, queens stay in the dark
9. Voices Against Brain Cancer Commends National Fencing Champion for His Positive Attitude and Will to Live
10. Molecule discovered that protects the brain from cannabis intoxication
11. Sleep to protect your brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... , ... January 24, 2017 , ... ... (AMIA) commended the Patient-Centered Outcomes Research Institute (PCORI) for developing a data access ... PCORI consider requiring a preliminary data sharing plan as part of award applications, ...
(Date:1/24/2017)... ... January 24, 2017 , ... ... offering, Processing Assurance Control Equipment (PACE), at the International Production and Processing Expo ... booth will highlight the new technology that is used in poultry processing facilities ...
(Date:1/24/2017)... ... 2017 , ... Learn to use popular brainwave and heart rhythm equipment to ... offered by Dr. Carol Francis at PVNET on Sundays in February and March and ... experiences. , Dr. Carol Francis shows business owners, parents, athletes, students and ...
(Date:1/24/2017)... ... January 24, 2017 , ... ... that it has officially formed a distribution partnership with Byers Scientific & ... odor management industry. , Through the agreement, OMI Industries formulated a special version ...
(Date:1/24/2017)... ... January 24, 2017 , ... This Saturday, January 28, the ... a very special performance by Alabama Symphony Orchestra musicians Yifan Zhou, Mara McClain & ... as dim sum, and exhibitors offer a look at Chinese games, crafts & more. ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)... , January 24, 2017 For today, ... GENE ), Alder Biopharmaceuticals Inc. (NASDAQ: ... ), and Egalet Corp. (NASDAQ: EGLT ). These ... lower on Monday, January 23 rd , 2017, with the ... health care companies in the S&P 500 also were down ...
(Date:1/24/2017)... 23, 2017 Optoelectronic components have the ... The interaction of these components with light makes ... range of applications. These components are primarily used ... and healthcare among others. Growing application ... low power consumption, reliability, scalability, and performance is ...
(Date:1/24/2017)... 2017 Laboratory Markets Limited has completed a ... spectrometry in both clinical and research laboratory settings. This ... size of $6.8 billion and growing to $9.2 billion ... the use of mass spectrometry across more than 5,200 ... investigated growth in the use of mass spectrometry in ...
Breaking Medicine Technology: